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SY SY - Synaptic Systems SY SY - Synaptic Systems

Arc - 156 002

A cytoskeleton-associated protein involved in neuronal plasticity

Polyclonal rabbit antiserum
350.00 USD
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Cat. No. 156 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 500 up to 1 : 2000 (AP staining) gallery  
IP: yes
ICC: not tested yet (see remarks)
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 396 from mouse Arc (UniProt Id: Q9WV31)
Reactivity Reacts with: rat (Q63053), mouse (Q9WV31).
No signal: zebrafish.
Other species not tested yet.
Specificity Specific for arc. (K.O. verified)
Remarks

ICC: The affinity purified antibody (cat. no. 156 003) is recommended.

Datasheet 156_002.pdf


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References for Arc - 156 002

The activity-regulated cytoskeleton-associated protein, Arc/Arg3.1, influences mouse cocaine self-administration.
Penrod RD, Thomsen M, Taniguchi M, Guo Y, Cowan CW, Smith LN
Pharmacology, biochemistry, and behavior (2019) : 172818. 156 002 WB; KO verified; tested species: mouse
Distinct miRNA expression in dorsal striatal subregions is associated with risk for addiction in rats.
Quinn RK, Brown AL, Goldie BJ, Levi EM, Dickson PW, Smith DW, Cairns MJ, Dayas CV
Translational psychiatry (2015) 5: e503. 156 002 WB
Memory-enhancing intra-basolateral amygdala infusions of clenbuterol increase Arc and CaMKIIα protein expression in the rostral anterior cingulate cortex.
Holloway-Erickson CM, McReynolds JR, McIntyre CK
Frontiers in behavioral neuroscience (2012) 6: 17. 156 002 WB
UPF2 leads to degradation of dendritically targeted mRNAs to regulate synaptic plasticity and cognitive function.
Notaras M, Allen M, Longo F, Volk N, Toth M, Li Jeon N, Klann E, Colak D
Molecular psychiatry (2019) : . 156 002 ICC; tested species: mouse
Temporal dynamics of Arc/Arg3.1 expression in the dorsal striatum during acquisition and consolidation of a motor skill in mice.
Gong WK, Ni J, Yu LF, Wang L, Huang ZL
Neurobiology of learning and memory (2020) : 107156. 156 002 IHC; tested species: mouse
c-Fos, Arc, and stargazin expression in rat eyeblink conditioning.
Kim S, Thompson RF
Behavioral neuroscience (2011) 1251: 117-23. 156 002 IHC; tested species: rat
The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat.
Thomsen MS, Mikkelsen JD, Timmermann DB, Peters D, Hay-Schmidt A, Martens H, Hansen HH
Neuroscience (2008) 1542: 741-53. 156 002 IHC; tested species: rat
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com