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SY SY - Synaptic Systems SY SY - Synaptic Systems

α-Tubulin

A major cytoskeleton protein

References SySy alpha-Tubulin antibodies

A vital role of tubulin-tyrosine-ligase for neuronal organization.
Erck C, Peris L, Andrieux A, Meissirel C, Gruber AD, Vernet M, Schweitzer A, Saoudi Y, Pointu H, Bosc C, Salin PA, et al.
Proceedings of the National Academy of Sciences of the United States of America (2005) 10222: 7853-8.
Association of tubulin carboxypeptidase with microtubules in living cells.
Contin MA, Sironi JJ, Barra HS, Arce CA
The Biochemical journal (1999) 339 ( Pt 2): 463-71.
Accumulation of delta 2-tubulin, a major tubulin variant that cannot be tyrosinated, in neuronal tissues and in stable microtubule assemblies.
Paturle-Lafanechère L, Manier M, Trigault N, Pirollet F, Mazarguil H, Job D
Journal of cell science (1994) 107 ( Pt 6): 1529-43.
Characterization of the tubulin-tyrosine ligase.
Ersfeld K, Wehland J, Plessmann U, Dodemont H, Gerke V, Weber K
The Journal of cell biology (1993) 1203: 725-32.
Class II tubulin, the major brain beta tubulin isotype is polyglutamylated on glutamic acid residue 435.
Rüdiger M, Plessman U, Klöppel KD, Wehland J, Weber K
FEBS letters (1992) 3081: 101-5.
Autoregulation of tubulin synthesis in hepatocytes and fibroblasts.
Caron JM, Jones AL, Kirschner MW
The Journal of cell biology (1985) 1015 Pt 1: 1763-72.
Autoregulation of tubulin synthesis in enucleated cells.
Caron JM, Jones AL, Rall LB, Kirschner MW
Nature () 3176038: 648-51.
The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications.
Götzke H, Kilisch M, Martínez-Carranza M, Sograte-Idrissi S, Rajavel A, Schlichthaerle T, Engels N, Jungmann R, Stenmark P, Opazo F, Frey S, et al.
Nature communications (2019) 101: 4403. 302 211 WB; tested species: mouse
SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors.
Koike S, Jahn R
Nature communications (2019) 101: 1608. 302 211 WB; tested species: human
Slowing ribosome velocity restores folding and function of mutant CFTR.
Oliver KE, Rauscher R, Mijnders M, Wang W, Wolpert MJ, Maya J, Sabusap CM, Kesterson RA, Kirk KL, Rab A, Braakman I, et al.
The Journal of clinical investigation (2019) : . 302 211 WB; tested species: human
Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity.
Yagensky O, Kohansal-Nodehi M, Gunaseelan S, Rabe T, Zafar S, Zerr I, Härtig W, Urlaub H, Chua JJ
eLife (2019) 8: . 302 211 WB; tested species: mouse
Truncated tau deregulates synaptic markers in rat model for human tauopathy.
Jadhav S, Katina S, Kovac A, Kazmerova Z, Novak M, Zilka N
Frontiers in cellular neuroscience (2015) 9: 24. 302 211 WB
BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons.
Shinoda Y, Ahmed S, Ramachandran B, Bharat V, Brockelt D, Altas B, Dean C
Frontiers in synaptic neuroscience (2014) 6: 27. 302 211 WB; tested species: rat
Developmental switch in the kinase dependency of long-term potentiation depends on expression of GluA4 subunit-containing AMPA receptors.
Luchkina NV, Huupponen J, Clarke VR, Coleman SK, Keinänen K, Taira T, Lauri SE
Proceedings of the National Academy of Sciences of the United States of America (2014) 11111: 4321-6. 302 217 WB; tested species: mouse,rat
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 302 203 WB, ICC, IHC; tested species: mouse,rat
Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission.
Spangler SA, Schmitz SK, Kevenaar JT, de Graaff E, de Wit H, Demmers J, Toonen RF, Hoogenraad CC
The Journal of cell biology (2013) 2016: 915-28. 302 211 WB; tested species: rat
Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion.
Xie L, Zhu D, Kang Y, Liang T, He Y, Gaisano HY
PloS one (2013) 87: e67561. 302 211 WB; tested species: human,mouse,rat
Ongoing intrinsic synchronous activity is required for the functional maturation of CA3-CA1 glutamatergic synapses.
Huupponen J, Molchanova SM, Lauri SE, Taira T
Cerebral cortex (New York, N.Y. : 1991) (2013) 2311: 2754-64. 302 217 WB; tested species: rat
Tubulin detyrosination promotes monolayer formation and apical trafficking in epithelial cells.
Zink S, Grosse L, Freikamp A, Bänfer S, Müksch F, Jacob R
Journal of cell science (2012) 125Pt 24: 5998-6008. 302 011 WB, ICC
A family of protein-deglutamylating enzymes associated with neurodegeneration.
Rogowski K, van Dijk J, Magiera MM, Bosc C, Deloulme JC, Bosson A, Peris L, Gold ND, Lacroix B, Bosch Grau M, Bec N, et al.
Cell (2010) 1434: 564-78. 302 011 WB
Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release.
Groffen AJ, Martens S, Díez Arazola R, Cornelisse LN, Lozovaya N, de Jong AP, Goriounova NA, Habets RL, Takai Y, Borst JG, Brose N, et al.
Science (New York, N.Y.) (2010) 3275973: 1614-8. 302 211 WB; tested species: mouse
Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system.
Xue M, Stradomska A, Chen H, Brose N, Zhang W, Rosenmund C, Reim K
Proceedings of the National Academy of Sciences of the United States of America (2008) 10522: 7875-80. 302 211 WB; tested species: mouse
Turnover of the carboxy-terminal tyrosine of alpha-tubulin and means of reaching elevated levels of detyrosination in living cells.
Wehland J, Weber K
Journal of cell science (1987) 88 ( Pt 2): 185-203. 302 011 WB, ICC
SF-Assemblin genes in Paramecium: phylogeny and phenotypes of RNAi silencing on the ciliary-striated rootlets and surface organization.
Nabi A, Yano J, Valentine MS, Picariello T, Van Houten JL
Cilia (2019) 8: 2. 302 011 ICC
Intrinsic refractive index matched 3D dSTORM with two objectives: Comparison of detection techniques.
Schmidt NC, Kahms M, Hüve J, Klingauf J
Scientific reports (2018) 81: 13343. 302 211 ICC; tested species: mouse
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy.
Richter KN, Revelo NH, Seitz KJ, Helm MS, Sarkar D, Saleeb RS, D'Este E, Eberle J, Wagner E, Vogl C, Lazaro DF, et al.
The EMBO journal (2018) 371: 139-159. 302 203 ICC; tested species: mouse
The Ciliary Protein IFT57 in the Macronucleus of Paramecium.
Shi L, Koll F, Arnaiz O, Cohen J
The Journal of eukaryotic microbiology (2017) : . 302 011 ICC
Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway.
Guillabert-Gourgues A, Jaspard-Vinassa B, Bats ML, Sewduth RN, Franzl N, Peghaire C, Jeanningros S, Moreau C, Roux E, Larrieu-Lahargue F, Dufourcq P, et al.
Molecular biology of the cell (2016) 276: 941-53. 302 011 ICC
Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.
Neupert C, Schneider R, Klatt O, Reissner C, Repetto D, Biermann B, Niesmann K, Missler M, Heine M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2015) 3540: 13629-47. 302 211 ICC
Mechanisms for axon maintenance and plasticity in motoneurons: alterations in motoneuron disease.
Jablonka S, Dombert B, Asan E, Sendtner M
Journal of anatomy (2014) 2241: 3-14. 302 011 ICC
Reduction of meckelin leads to general loss of cilia, ciliary microtubule misalignment and distorted cell surface organization.
Picariello T, Valentine MS, Yano J, Van Houten J
Cilia (2014) 31: 2. 302 011 ICC
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 302 203 WB, ICC, IHC; tested species: mouse,rat
Tubulin detyrosination promotes monolayer formation and apical trafficking in epithelial cells.
Zink S, Grosse L, Freikamp A, Bänfer S, Müksch F, Jacob R
Journal of cell science (2012) 125Pt 24: 5998-6008. 302 011 WB, ICC
Hypoxia stimulates carcinoma invasion by stabilizing microtubules and promoting the Rab11 trafficking of the alpha6beta4 integrin.
Yoon SO, Shin S, Mercurio AM
Cancer research (2005) 657: 2761-9. 302 011 ICC
Turnover of the carboxy-terminal tyrosine of alpha-tubulin and means of reaching elevated levels of detyrosination in living cells.
Wehland J, Weber K
Journal of cell science (1987) 88 ( Pt 2): 185-203. 302 011 WB, ICC
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 302 203 WB, ICC, IHC; tested species: mouse,rat
Monocilia on chicken embryonic endocardium in low shear stress areas.
Van der Heiden K, Groenendijk BC, Hierck BP, Hogers B, Koerten HK, Mommaas AM, Gittenberger-de Groot AC, Poelmann RE
Developmental dynamics : an official publication of the American Association of Anatomists (2006) 2351: 19-28. 302 011 IHC
Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Szyk A, Deaconescu AM, Piszczek G, Roll-Mecak A
Nature structural & molecular biology (2011) 1811: 1250-8. 302 011
Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin.
Roll-Mecak A, Vale RD
Nature (2008) 4517176: 363-7. 302 011
Two catalytic domains are required for protein deacetylation.
Zhang Y, Gilquin B, Khochbin S, Matthias P
The Journal of biological chemistry (2006) 2815: 2401-4. 302 011
Coordination of microtubule and microfilament dynamics by Drosophila Rho1, Spire and Cappuccino.
Rosales-Nieves AE, Johndrow JE, Keller LC, Magie CR, Pinto-Santini DM, Parkhurst SM
Nature cell biology (2006) 84: 367-76. 302 011
Monoclonal antibody ID5: epitope characterization and minimal requirements for the recognition of polyglutamylated alpha- and beta-tubulin.
Rüdiger AH, Rüdiger M, Wehland J, Weber K
European journal of cell biology (1999) 781: 15-20. 302 011
Primary cilia in cultured mammalian cells: detection with an antibody against detyrosinated alpha-tubulin (ID5) and by electron microscopy.
Wheatley DN, Feilen EM, Yin Z, Wheatley SP
Journal of submicroscopic cytology and pathology (1994) 261: 91-102. 302 011
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Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com