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SY SY - Synaptic Systems SY SY - Synaptic Systems

c-Fos - 226 003

A member of the transcription factor complex AP1

Polyclonal rabbit purified antibody
370.00 USD
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Cat. No. 226 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 250 up to 1 : 500 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P/FFPE: 1 : 1000 gallery  
Immunogen Synthetic peptide corresponding to AA 2 to 17 from rat c-Fos (UniProt Id: P12841)
Reactivity Reacts with: human (P01100), rat (P12841), mouse (P01101), monkey, ape, cow, dog, pig.
Other species not tested yet.
Specificity Specific for c-Fos.
matching control protein/peptide 226-0P
Datasheet 226_003.pdf

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References for c-Fos - 226 003

Human osteosarcoma cells respond to sorafenib chemotherapy by downregulation of the tumor progression factors S100A4, CXCR4 and the oncogene FOS.
Walter I, Wolfesberger B, Miller I, Mair G, Burger S, Gallè B, Steinborn R
Oncology reports (2014) 313: 1147-56. 226 003 ICC; tested species: human
Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
Tan LL, Oswald MJ, Heinl C, Retana Romero OA, Kaushalya SK, Monyer H, Kuner R
Nature communications (2019) 101: 983. 226 003 IHC; tested species: mouse
Enhanced activity of pyramidal neurons in the infralimbic cortex drives anxiety behavior.
Berg L, Eckardt J, Masseck OA
PloS one (2019) 141: e0210949. 226 003 IHC; tested species: mouse
A novel large animal model of recurrent migraine established by repeated administration of inflammatory soup into the dura mater of the rhesus monkey.
Chen N, Su W, Cui SH, Guo J, Duan JC, Li HX, He L
Neural regeneration research (2019) 141: 100-106. 226 003 IHC; tested species: monkey
Nucleus incertus ablation disrupted conspecific recognition and modified immediate early gene expression patterns in 'social brain' circuits of rats.
García-Díaz C, Sánchez-Catalán MJ, Castro-Salazar E, García-Avilés A, Albert-Gascó H, de la Bárcena SS, Sánchez-Pérez AM, Gundlach AL, Olucha-Bordonau FE
Behavioural brain research (2018) : . 226 003 IHC; tested species: rat
Spatial Memory Engram in the Mouse Retrosplenial Cortex.
Milczarek MM, Vann SD, Sengpiel F
Current biology : CB (2018) 2812: 1975-1980.e6. 226 003 IHC; tested species: mouse
Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation.
Gelegen C, Miracca G, Ran MZ, Harding EC, Ye Z, Yu X, Tossell K, Houston CM, Yustos R, Hawkins ED, Vyssotski AL, et al.
Current biology : CB (2018) 284: 580-587.e5. 226 003 IHC; tested species: mouse
Activation of the rat hypothalamic supramammillary nucleus by food anticipation, food restriction or ghrelin administration.
Le May MV, Hume C, Sabatier N, Schéle E, Bake T, Bergström U, Menzies J, Dickson SL
Journal of neuroendocrinology (2018) : e12676. 226 003 IHC; tested species: rat
Calretinin Neurons in the Midline Thalamus Modulate Starvation-Induced Arousal.
Hua R, Wang X, Chen X, Wang X, Huang P, Li P, Mei W, Li H
Current biology : CB (2018) : . 226 003 IHC; tested species: mouse
Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits.
Zhou QG, Nemes AD, Lee D, Ro EJ, Zhang J, Nowacki AS, Dymecki SM, Najm IM, Suh H
The Journal of clinical investigation (2018) : . 226 003 IHC; tested species: mouse
In renovascular hypertension, TNF-α type-1 receptors in the area postrema mediate increases in cardiac and renal sympathetic nerve activity and blood pressure.
Korim WS, Elsaafien K, Basser JR, Setiadi A, May CN, Yao ST
Cardiovascular research (2018) : . 226 003 IHC; tested species: rat
Lipopolysaccharide Challenge Reveals Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Murine Systemic Lupus Erythematosus.
Pham GS, Mathis KW
Brain sciences (2018) 810: . 226 003 IHC; tested species: mouse
Social stress-potentiated methamphetamine seeking.
Blouin AM, Pisupati S, Hoffer CG, Hafenbreidel M, Jamieson SE, Rumbaugh G, Miller CA
Addiction biology (2018) : . 226 003 IHC; tested species: rat
Astrocytic Activation Generates De Novo Neuronal Potentiation and Memory Enhancement.
Adamsky A, Kol A, Kreisel T, Doron A, Ozeri-Engelhard N, Melcer T, Refaeli R, Horn H, Regev L, Groysman M, London M, et al.
Cell (2018) : . 226 003 IHC; tested species: mouse
A GLP-1:CCK fusion peptide harnesses the synergistic effects on metabolism of CCK-1 and GLP-1 receptor agonism in mice.
Hornigold DC, Roth E, Howard V, Will S, Oldham S, Coghlan MP, Blouet C, Trevaskis JL
Appetite (2018) : . 226 003 IHC; tested species: mouse
Intragastric preloads of l-tryptophan reduce ingestive behavior via oxytocinergic neural mechanisms in male mice.
Gartner SN, Aidney F, Klockars A, Prosser C, Carpenter EA, Isgrove K, Levine AS, Olszewski PK
Appetite (2018) 125: 278-286. 226 003 IHC; tested species: mouse
Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations.
Tasaka GI, Guenthner CJ, Shalev A, Gilday O, Luo L, Mizrahi A
Nature communications (2018) 91: 871. 226 003 IHC; tested species: mouse
Dorsal CA1 interneurons contribute to acute stress-induced spatial memory deficits.
Yu JY, Fang P, Wang C, Wang XX, Li K, Gong Q, Luo BY, Wang XD
Neuropharmacology (2018) : . 226 003 IHC; tested species: mouse
High-Sugar, but Not High-Fat, Food Activates Supraoptic Nucleus Neurons in the Male Rat.
Hume C, Sabatier N, Menzies J
Endocrinology (2017) 1587: 2200-2211. 226 003 IHC; tested species: rat
Downregulation of KCNMB4 expression and changes in BK channel subtype in hippocampal granule neurons following seizure activity.
Whitmire LE, Ling L, Bugay V, Carver CM, Timilsina S, Chuang HH, Jaffe DB, Shapiro MS, Cavazos JE, Brenner R
PloS one (2017) 1211: e0188064. 226 003 IHC; tested species: mouse
A mutant with bilateral whisker to barrel inputs unveils somatosensory mapping rules in the cerebral cortex.
Renier N, Dominici C, Erzurumlu RS, Kratochwil CF, Rijli FM, Gaspar P, Chédotal A
eLife (2017) 6: . 226 003 IHC; tested species: mouse
mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice.
Burke LK, Darwish T, Cavanaugh AR, Virtue S, Roth E, Morro J, Liu SM, Xia J, Dalley JW, Burling K, Chua S, et al.
eLife (2017) 6: . 226 003 IHC; tested species: mouse
Effects of lateral olfactory tract stimulation on Fos immunoreactivity in vasopressin neurones of the rat piriform cortex.
Tsuji C, Tsuji T, Allchorne A, Leng G, Ludwig M
Journal of neuroendocrinology (2017) 2911: . 226 003 IHC; tested species: rat
Cerebellar perineuronal nets in cocaine-induced pavlovian memory: Site matters.
Carbo-Gas M, Moreno-Rius J, Guarque-Chabrera J, Vazquez-Sanroman D, Gil-Miravet I, Carulli D, Hoebeek F, De Zeeuw C, Sanchis-Segura C, Miquel M
Neuropharmacology (2017) 125: 166-180. 226 003 IHC; tested species: mouse
Activation of perineuronal net-expressing excitatory neurons during associative memory encoding and retrieval.
Morikawa S, Ikegaya Y, Narita M, Tamura H
Scientific reports (2017) 7: 46024. 226 003 IHC; tested species: mouse
Detecting and discriminating novel objects: The impact of perirhinal cortex disconnection on hippocampal activity patterns.
Kinnavane L, Amin E, Olarte-Sánchez CM, Aggleton JP
Hippocampus (2016) 2611: 1393-1413. 226 003 IHC
Parallel Arousal Pathways in the Lateral Hypothalamus.
Heiss JE, Yamanaka A, Kilduff TS
eNeuro () 54: . 226 003 IHC; tested species: mouse
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: | E-Mail: