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GluN2B antibody - 244 115

GluN2A and B are subunits of ionotropic NMDA type glutamate receptors
Guinea pig polyclonal purified antibody
Cat. No.: 244 115
Amount: 50 µg
Price: $460.00
Cat. No. 244 115 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not recommended
IHC: not recommended
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 918 to 1470 from rat GluN2B (UniProt Id: Q00960)
Reactivity Reacts with: rat (Q00960), mouse (Q01097).
Other species not tested yet.
Specificity Specific for GluN 2B, no cross-reactivity to GluN 2A.
Data sheet 244_115.pdf
Cat. No.: 244 115
Amount: 50 µg
Price: $460.00
Background

GluNs (NMDA-receptors) represent a class of glutamate receptors that are of central importance in synaptic plasticity. Multiple NMDA receptor subtypes exist: GluN 1 and GluN 2 A-D. GluN 1 is the most important as it is required for activity. NMDA-receptors allow Ca2+ influx and are thought to trigger Ca2+ dependent postsynaptic processes involved in long term potentiation and depression.