Cat. No.: 426 003
Amount: 50 µg
Price:
$375.00
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| Cat. No. 426 003 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet |
| Immunogen | Recombinant protein corresponding to AA 1 to 100 from human RNF126 (UniProt Id: Q9BV68) |
| Reactivity |
Reacts with: human (Q9BV68), rat (Q499Q1), mouse (Q91YL2). Other species not tested yet. |
| Data sheet | 426_003.pdf |
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RNF 126 is an E3 ubiquitin ligase that collaborates with the BAG6 sortase complex to ubiquitinate hydrophobic substrates in the cytoplasm that are targeted for proteasomal recycling.
It belongs to the family of RING E3 ligases and consists of an N-terminal zinc-finger and a C- terminal RING domain.
RNF 126 has also been shown to be involved in promotion of cancer growth.