VGAT (SLC32A1) peptide cytoplasmic domain - 131-0P

VGAT or VIAAT is the GABA and glycine transporter in the membrane of synaptic vesicles

control peptide

Cat. No.: 131-0P

Amount: 100 µg

Price: $110.00

Please note that import duties may still apply, which will be billed to you directly by the shipping carrier.

Cat. No. 131-0P	100 µg peptide, lyophilized. For reconstitution add 100 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized!
Applications
Immunogen	Synthetic peptide corresponding to residues near the amino terminus of rat VGAT (UniProt Id: O35458)
Recommended dilution	Optimal concentrations should be determined by the end-user.
Matching antibodies	131 002, 131 003, 131 011, 131 011BT, 131 011C2, 131 011C3, 131 008, 131 308, 131 009
Remarks	This control peptide consists of the synthetic peptide (AEPPVEGDIHYQR) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.
Data sheet	Data Sheet 131-0p Safety Data Sheet (SDS)

Cat. No.: 131-0P

Amount: 100 µg

Price: $110.00

Background

The vesicular GABA transporter VGAT is responsible for uptake and storage of GABA and glycine by synaptic vesicles in the central nervous system. For this reason it is frequently referred to as the vesicular inhibitory aminoacid transporter VIAAT. It is different from the plasma membrane transporters in that it is driven by a proton electrochemical gradient across the vesicle membrane. So far, only one isoform is known. VGAT is currently the best marker for inhibitory nerve terminals.

For more information on protein expression pattern, please refer to the overview image in our SYSY Antibodies ATLAS.

1 ) Chaudhry FA et al., J. Neurosci. (1998)
2 ) McIntire SL et al., Nature (1997)
3 ) Sagné C et al., FEBS Lett. (1997)
4 ) Hell JW et al., EMBO J. (1988)

Other products for this target