print page Visit us on Instagram Visit us on Facebook Visit us on Twitter Visit us on LinkedIn
SY SY - Synaptic Systems SY SY - Synaptic Systems

Homer 1 - 160 002

A post synaptic density (PSD) protein involved in the targeting of glutamate receptors

Polyclonal rabbit antiserum
350.00 USD
select country for shop
Cat. No. 160 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 up to 1 : 1000 (see remarks) gallery  
IHC: yes
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 196 from human Homer1 (UniProt Id: Q86YM7)
Reactivity Reacts with: human (Q86YM7), rat (Q9Z214), mouse (Q9Z2Y3).
Other species not tested yet.
Specificity Specific for Homer 1. Cross-reactivity of the serum to Homer 2 and 3 was removed by pre-adsorption with Homer 2 (aa 1 - 176) and Homer 3 (aa 1 - 177).
According to Soloviev et al. (2000), aa 1 - 180 are present in isoforms a, b, c and d.
matching control protein/peptide 160-0P
Remarks

ICC: PFA fixation is recommended.
Methanol fixation leads to a complete loss of the signal.

Datasheet 160_002.pdf


For online shopping select your country:
If your country is not listed, please contact us by email to sales@sysy.com or contact your local distributor.




References for Homer 1 - 160 002

Differential α2A- and α2C-adrenoceptor protein expression in presynaptic and postsynaptic density fractions of postmortem human prefrontal cortex.
Erdozain AM, Brocos-Mosquera I, Gabilondo AM, Meana JJ, Callado LF
Journal of psychopharmacology (Oxford, England) (2018) : 269881118798612. 160 002 WB; tested species: human
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Dejanovic B, Huntley MA, De Mazière A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, et al.
Neuron (2018) : . 160 002 WB, ICC; tested species: mouse
Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology.
Bodaleo FJ, Montenegro-Venegas C, Henríquez DR, Court FA, Gonzalez-Billault C
Scientific reports (2016) 6: 30069. 160 002 WB, ICC
Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis.
Smalla KH, Sahin J, Putzke J, Tischmeyer W, Gundelfinger ED, Kreutz MR
Neurochemical research (2009) 348: 1405-9. 160 002 WB
In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.
Spence EF, Dube S, Uezu A, Locke M, Soderblom EJ, Soderling SH
Nature communications (2019) 101: 386. 160 002 ICC; tested species: mouse
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Dejanovic B, Huntley MA, De Mazière A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, et al.
Neuron (2018) : . 160 002 WB, ICC; tested species: mouse
APC2 controls dendrite development by promoting microtubule dynamics.
Kahn OI, Schätzle P, van de Willige D, Tas RP, Lindhout FW, Portegies S, Kapitein LC, Hoogenraad CC
Nature communications (2018) 91: 2773. 160 002 ICC; tested species: rat
Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology.
Bodaleo FJ, Montenegro-Venegas C, Henríquez DR, Court FA, Gonzalez-Billault C
Scientific reports (2016) 6: 30069. 160 002 WB, ICC
Dorsal Horn Gastrin-Releasing Peptide Expressing Neurons Transmit Spinal Itch But Not Pain Signals.
Albisetti GW, Pagani M, Platonova E, Hösli L, Johannssen HC, Fritschy JM, Wildner H, Zeilhofer HU
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 160 002 IHC; tested species: mouse
Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican.
Favuzzi E, Marques-Smith A, Deogracias R, Winterflood CM, Sánchez-Aguilera A, Mantoan L, Maeso P, Fernandes C, Ewers H, Rico B
Neuron (2017) 953: 639-655.e10. 160 002 IHC; tested species: mouse
Identification of Two Classes of Somatosensory Neurons That Display Resistance to Retrograde Infection by Rabies Virus.
Albisetti GW, Ghanem A, Foster E, Conzelmann KK, Zeilhofer HU, Wildner H
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3743: 10358-10371. 160 002 IHC; tested species: mouse
Synaptic Systems Gesellschaft für neurobiologische Forschung, Entwicklung und Produktion mbH | Rudolf-Wissell-Str. 28 | 37079 Goettingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com | Impressum - Legal Note | Privacy Policy
Design by BLACKBIT interactive GmbH

Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com