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FluoTags are camelid single domain antibodies consisting only of one antigen binding site of a Alpaka heavy chain antibody. With only ~15 kDa, these Tags are about 10-times smaller than conventional IgG antibody molecules.
|Cat. No. N3702-AF647-L||
2.5 µM fluorescently labeled sdAb in buffered saline, 50% glycerol, 0.09% sodium azide
|Storage||–80°C for up to 12 month|
IP: not tested yet
ICC: 1 : 500
IHC: 1 : 200 up to 1 : 500
IHC-P/FFPE: not tested yet
|Label||Alexa 647, two fluorophores coupled to one FluoTag|
|Immunogen||Recombinant protein corresponding to AA 68 to 251 from mouse PSD95 (UniProt Id: Q62108)|
Reacts with: mouse (Q62108), rat (P31016).
Other species not tested yet.
|Specificity||Specific for PSD 95|
|Matching control protein/peptide||124-01P|
PSD95 (postsynaptic density protein 95 kDa, also called SAP 90: synapse associated protein of 90 kDa and DLG 4) is a component of postsynaptic densities in central synapses. It contains three PDZ domains. The first and second PDZ domain localizes NMDA receptors and K+ channels to synapses, the third binds to neuroligins which are neuronal cell adhesion molecules that interact with β-neurexins and form intercellular junctions. Thus different PDZ domains of PSD 95 might be specialized for distinct functions.