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Aquaporin4 antibody - 429 008

Aquaporin4 is a water-specific channel in the blood brain barrier
Rabbit monoclonal recombinant IgG
Cat. No.: 429 008
Amount: 50 µg
Price: $415.00
Cat. No. 429 008 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
WB: not tested yet
IP: yes
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: 1 : 4000 gallery  
IHC-Fr: 1 : 500 up to 1 : 1000 (see remarks) gallery  
Clone Rb325B5A5
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to AA 249 to 323 from mouse Aquaporin-4 isoform 2 (UniProt Id: P55088-1)
Reactivity Reacts with: mouse (P55088-1), rat (P47863), human (P55087).
Other species not tested yet.
Matching control protein/peptide 429-0P

This antibody is a chimeric antibody based on the well known monoclonal mouse antibody clone 325B5A5. The constant regions of the heavy and light chains have been replaced with rabbit specific sequences. Therefore, the antibody can be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells
IHC-Fr: Methanol fixation is recommended.

Data sheet 429_008.pdf
Cat. No.: 429 008
Amount: 50 µg
Price: $415.00

Aquaporin4, or AQP4, also known as Mercurial-insensitive water channel (MIWC), is a member of the aquaporin water channel family. This osmoreceptor regulates body water balance and mediates water flow within the central nervous system.