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TMEM119 antibody - 400 004

TMEM119 is a microglia specific transmembrane protein
Polyclonal Guinea pig antiserum
Cat. No.: 400 004
Amount: 100 µl
Price: $350.00
Cat. No. 400 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 189 to 280 from mouse TMEM119 (UniProt Id: Q8R138)
Reactivity Reacts with: mouse (Q8R138).
Other species not tested yet.
Specificity specific for TMEM 119
Remarks

This antibody is recommended for mouse only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely.

Data sheet 400_004.pdf

References for TMEM119 - 400 004

CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10.
Guldner IH, Wang Q, Yang L, Golomb SM, Zhao Z, Lopez JA, Brunory A, Howe EN, Zhang Y, Palakurthi B, Barron M, et al.
Cell (2020) : . 400 004 IHC-P; tested species: mouse
Cat. No.: 400 004
Quantity: 100 µl
Price: $350.00
CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10.
Guldner IH, Wang Q, Yang L, Golomb SM, Zhao Z, Lopez JA, Brunory A, Howe EN, Zhang Y, Palakurthi B, Barron M, et al.
Cell (2020) : . 400 004 IHC-P; tested species: mouse
Background
Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM 119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.