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UCHL 1 antibody - 233 002

UCHL1 or PGP9.5 is a neuron specific member of the ubiquitin proteasome system.
Polyclonal rabbit antiserum
Cat. No.: 233 002
Amount: 200 µl
Price: $350.00
Cat. No. 233 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 6 to 223 from rat UCHL1 (UniProt Id: Q00981)
Reactivity Reacts with: rat (Q00981), mouse (Q9R0P9).
No signal: zebrafish.
Other species not tested yet.
Specificity Specific for UCHL 1
Data sheet 233_002.pdf
Cat. No.: 233 002
Quantity: 200 µl
Price: $350.00
Background
The Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCHL 1) enzyme is a member of a protein family involved in the hydrolyzation of C-terminal adducts of polymeric ubiquitin to generate monomeric ubiquitin. It is abundantly expressed in neurons throughout the brain and belongs to the ubiquitin-proteasome system. This pathway is responsible for the degradation of misfolded and damaged proteins and has been postulated to play an important role in Parkinson's disease.