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Homer 2 antibody - 160 204

Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors
Guinea pig polyclonal antiserum
Cat. No.: 160 204
Amount: 100 µl
Price: $350.00
Cat. No. 160 204 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications
 
WB: yes limited (see remarks)
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 176 from rat Homer2 (UniProt Id: O88801)
Reactivity Reacts with: mouse (Q9QWW1), rat (O88801).
Other species not tested yet.
Specificity Specific for Homer 2
Remarks

WB: The rabbit antibody cat. no. 160 203 is more sensitive and recommended.

Data sheet 160_204.pdf
Cat. No.: 160 204
Amount: 100 µl
Price: $350.00
Background

Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, Homer was suggested to organize distinct signalling domains.
Three isoforms, Homer 1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.