Cat. No.: 160 204
Amount: 100 µl
Price:
$365.00
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| Cat. No. 160 204 |
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 1 to 176 from rat Homer2 (UniProt Id: O88801) |
| Reactivity |
Reacts with: mouse (Q9QWW1), rat (O88801). Other species not tested yet. |
| Remarks |
WB: The rabbit antibody cat. no. 160 203 is more sensitive and recommended. |
| Data sheet | 160_204.pdf |
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Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, Homer was suggested to organize distinct signalling domains.
Three isoforms, Homer 1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.