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Homer1 antibody - 160 003

Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors
Rabbit polyclonal purified antibody
Cat. No.: 160 003
Amount: 50 µg
Price: $465.00
Cat. No. 160 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 up to 1 : 1000 (see remarks) gallery  
IHC: 1 : 200 gallery  
IHC-P: 1 : 500 up to 1 : 1000 gallery  
ExM: yes
DNA-PAINT: 1 : 500
ELISA: yes (see remarks)
Immunogen Recombinant protein corresponding to the N-terminal half of human Homer 1 (UniProt Id: Q86YM7)
Reactivity Reacts with: human (Q86YM7), rat (Q9Z214), mouse (Q9Z2Y3).
Other species not tested yet.
Specificity Specific for Homer 1. Cross-reactivity of the serum to Homer 2 and 3 was removed by pre-adsorption with Homer 2 (aa 1 - 176) and Homer 3 (aa 1 - 177).
Matching control protein/peptide 160-0P
Remarks

ICC: PFA fixation is recommended.
ELISA: Suitable as detector antibody for sandwich-ELISA with cat. no. 160 011 as capture antibody. The ELISA-protocol for membrane proteins is recommended.
Data sheet 160_003.pdf

References for Homer1 - 160 003

Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
Monsorno K, Ginggen K, Ivanov A, Buckinx A, Lalive AL, Tchenio A, Benson S, Vendrell M, D'Alessandro A, Beule D, Pellerin L, et al.
Nature communications (2023) 141: 5749. 160 003 WB, IHC; tested species: mouse
Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus.
Lloyd BA, Han Y, Roth R, Zhang B, Aoto J
Nature communications (2023) 141: 4706. 160 003 WB; tested species: mouse
Developmental Pb exposure increases AD risk via altered intracellular Ca2+ homeostasis in hiPSC-derived cortical neurons.
Xie J, Wu S, Szadowski H, Min S, Yang Y, Bowman AB, Rochet JC, Freeman JL, Yuan C
The Journal of biological chemistry (2023) : 105023. 160 003 WB, ICC; tested species: human
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity.
Hsieh YC, Negri J, He A, Pearse RV, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL
Molecular neurodegeneration (2022) 171: 61. 160 003 WB, ICC; tested species: human
Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy.
Gozzelino L, Kochlamazashvili G, Baldassari S, Mackintosh AI, Licchetta L, Iovino E, Liu YC, Bennett CA, Bennett MF, Damiano JA, Zsurka G, et al.
Brain : a journal of neurology (2022) 1457: 2313-2331. 160 003 WB; tested species: mouse
Nrg1 haploinsufficiency alters inhibitory cortical circuits.
Navarro-Gonzalez C, Carceller H, Benito Vicente M, Serra I, Navarrete M, Domínguez-Canterla Y, Rodríguez-Prieto Á, González-Manteiga A, Fazzari P
Neurobiology of disease (2021) 157: 105442. 160 003 WB; tested species: mouse
Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice.
Prieto M, Folci A, Poupon G, Schiavi S, Buzzelli V, Pronot M, François U, Pousinha P, Lattuada N, Abelanet S, Castagnola S, et al.
Nature communications (2021) 121: 1557. 160 003 WB, ICC; tested species: mouse
Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.
Yilmaz M, Yalcin E, Presumey J, Aw E, Ma M, Whelan CW, Stevens B, McCarroll SA, Carroll MC
Nature neuroscience (2021) 242: 214-224. 160 003 WB, IHC; tested species: mouse
Proteome dynamics during homeostatic scaling in cultured neurons.
Dörrbaum AR, Alvarez-Castelao B, Nassim-Assir B, Langer JD, Schuman EM
eLife (2020) 9: . 160 003 WB; tested species: rat
Selective disruption of inhibitory synapses leading to neuronal hyperexcitability at an early stage of tau pathogenesis in a mouse model.
Shimojo M, Takuwa H, Takado Y, Tokunaga M, Tsukamoto S, Minatohara K, Ono M, Seki C, Maeda J, Urushihata T, Minamihisamatsu T, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 160 003 WB; tested species: mouse
Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum.
Zhang RS, Liakath-Ali K, Südhof TC
eLife (2020) 9: . 160 003 WB, IHC; tested species: mouse
SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.
Sessa A, Fagnocchi L, Mastrototaro G, Massimino L, Zaghi M, Indrigo M, Cattaneo S, Martini D, Gabellini C, Pucci C, Fasciani A, et al.
Neuron (2019) : . 160 003 WB; tested species: mouse
Fluoxetine Suppresses Glutamate- and GABA-Mediated Neurotransmission by Altering SNARE Complex.
Lazarevic V, Mantas I, Flais I, Svenningsson P
International journal of molecular sciences (2019) 2017: . 160 003 WB; tested species: rat
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer NJ, Ma R, Nakayama L, Monbureau M, Defensor E, Schüle B, Shamloo M, et al.
Acta neuropathologica (2019) : . 160 003 WB; tested species: mouse
Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors.
Cromberg LE, Saez TMM, Otero MG, Tomasella E, Alloatti M, Damianich A, Devoto VP, Ferrario J, Gelman D, Rubinstein M, Falzone TL, et al.
Journal of neurochemistry (2019) : . 160 003 WB; tested species: human
Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study.
Aguayo FI, Tejos-Bravo M, Díaz-Véliz G, Pacheco A, García-Rojo G, Corrales W, Olave FA, Aliaga E, Ulloa JL, Avalos AM, Román-Albasini L, et al.
Frontiers in molecular neuroscience (2018) 11: 283. 160 003 WB; tested species: rat
Homer1a drives homeostatic scaling-down of excitatory synapses during sleep.
Diering GH, Nirujogi RS, Roth RH, Worley PF, Pandey A, Huganir RL
Science (New York, N.Y.) (2017) 3556324: 511-515. 160 003 WB, IP; tested species: mouse
Distinct Defects in Synaptic Differentiation of Neocortical Neurons in Response to Prenatal Valproate Exposure.
Iijima Y, Behr K, Iijima T, Biemans B, Bischofberger J, Scheiffele P
Scientific reports (2016) 6: 27400. 160 003 WB
How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.
Acuna C, Liu X, Südhof TC
Neuron (2016) 914: 792-807. 160 003 WB
Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation.
Tao-Cheng JH, Thein S, Yang Y, Reese TS, Gallant PE
Neuroscience (2014) 266: 80-90. 160 003 WB, EM; tested species: rat
SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.
Iijima T, Wu K, Witte H, Hanno-Iijima Y, Glatter T, Richard S, Scheiffele P
Cell (2011) 1477: 1601-14. 160 003 WB; tested species: mouse
Homer1a drives homeostatic scaling-down of excitatory synapses during sleep.
Diering GH, Nirujogi RS, Roth RH, Worley PF, Pandey A, Huganir RL
Science (New York, N.Y.) (2017) 3556324: 511-515. 160 003 WB, IP; tested species: mouse
The human milk component myo-inositol promotes neuronal connectivity.
Paquette AF, Carbone BE, Vogel S, Israel E, Maria SD, Patil NP, Sah S, Chowdhury D, Kondratiuk I, Labhart B, Morrow AL, et al.
Proceedings of the National Academy of Sciences of the United States of America (2023) 12030: e2221413120. 160 003 ICC, IHC; tested species: human,rat
Developmental Pb exposure increases AD risk via altered intracellular Ca2+ homeostasis in hiPSC-derived cortical neurons.
Xie J, Wu S, Szadowski H, Min S, Yang Y, Bowman AB, Rochet JC, Freeman JL, Yuan C
The Journal of biological chemistry (2023) : 105023. 160 003 WB, ICC; tested species: human
Hippocampal dendritic spines express the RyR3 but not the RyR2 ryanodine receptor isoform.
Vega-Vásquez I, Lobos P, Toledo J, Adasme T, Paula-Lima A, Hidalgo C
Biochemical and biophysical research communications (2022) 633: 96-103. 160 003 ICC, ExM; tested species: rat
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity.
Hsieh YC, Negri J, He A, Pearse RV, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL
Molecular neurodegeneration (2022) 171: 61. 160 003 WB, ICC; tested species: human
Deficiency of protocadherin 9 leads to reduction in positive emotional behaviour.
Uemura M, Furuse T, Yamada I, Kushida T, Abe T, Imai K, Nagao S, Kudoh M, Yoshizawa K, Tamura M, Kiyonari H, et al.
Scientific reports (2022) 121: 11933. 160 003 ICC; tested species: mouse
α-Synuclein induced cholesterol lowering increases tonic and reduces depolarization-evoked synaptic vesicle recycling and glutamate release.
Lazarevic V, Yang Y, Paslawski W, Svenningsson P
NPJ Parkinson's disease (2022) 81: 71. 160 003 ICC; tested species: mouse
A Neuron, Microglia, and Astrocyte Triple Co-culture Model to Study Alzheimer's Disease.
Luchena C, Zuazo-Ibarra J, Valero J, Matute C, Alberdi E, Capetillo-Zarate E
Frontiers in aging neuroscience (2022) 14: 844534. 160 003 ICC; tested species: rat
Long-Term Cultures of Spinal Cord Interneurons.
Vargova I, Kriska J, Kwok JCF, Fawcett JW, Jendelova P
Frontiers in cellular neuroscience (2022) 16: 827628. 160 003 ICC; tested species: mouse
A multimodal 3D neuro-microphysiological system with neurite-trapping microelectrodes.
Molina-Martínez B, Jentsch LV, Ersoy F, van der Moolen M, Donato S, Ness TV, Heutink P, Jones PD, Cesare P
Biofabrication (2022) 142: . 160 003 ICC; tested species: mouse
Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice.
Prieto M, Folci A, Poupon G, Schiavi S, Buzzelli V, Pronot M, François U, Pousinha P, Lattuada N, Abelanet S, Castagnola S, et al.
Nature communications (2021) 121: 1557. 160 003 WB, ICC; tested species: mouse
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.
Kuijpers M, Kochlamazashvili G, Stumpf A, Puchkov D, Swaminathan A, Lucht MT, Krause E, Maritzen T, Schmitz D, Haucke V
Neuron (2021) 1092: 299-313.e9. 160 003 ICC; tested species: mouse
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids.
Trujillo CA, Adams JW, Negraes PD, Carromeu C, Tejwani L, Acab A, Tsuda B, Thomas CA, Sodhi N, Fichter KM, Romero S, et al.
EMBO molecular medicine (2021) 131: e12523. 160 003 ICC; tested species: human
Presynaptic activity and protein turnover are correlated at the single-synapse level.
Jähne S, Mikulasch F, Heuer HGH, Truckenbrodt S, Agüi-Gonzalez P, Grewe K, Vogts A, Rizzoli SO, Priesemann V
Cell reports (2021) 3411: 108841. 160 003 ICC; tested species: rat
TRPV1 Antagonist Prevents Neonatal Sevoflurane-Induced Synaptic Abnormality and Cognitive Impairment in Mice Through Regulating the Src/Cofilin Signaling Pathway.
Liu Y, Yang H, Fu Y, Pan Z, Qiu F, Xu Y, Yang X, Chen Q, Ma D, Liu Z
Frontiers in cell and developmental biology (2021) 9: 684516. 160 003 ICC; tested species: mouse
Latrophilin GPCR signaling mediates synapse formation.
Sando R, Südhof TC
eLife (2021) 10: . 160 003 ICC; tested species: mouse
Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease.
Werneburg S, Jung J, Kunjamma RB, Ha SK, Luciano NJ, Willis CM, Gao G, Biscola NP, Havton LA, Crocker SJ, Popko B, et al.
Immunity (2020) 521: 167-182.e7. 160 003 ICC; tested species: mouse
Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates.
Micali N, Kim SK, Diaz-Bustamante M, Stein-O'Brien G, Seo S, Shin JH, Rash BG, Ma S, Wang Y, Olivares NA, Arellano JI, et al.
Cell reports (2020) 315: 107599. 160 003 ICC; tested species: human
Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development.
Bikbaev A, Ciuraszkiewicz-Wojciech A, Heck J, Klatt O, Freund R, Mitlöhner J, Enrile Lacalle S, Sun M, Repetto D, Frischknecht R, Ablinger C, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) 4025: 4824-4841. 160 003 ICC; tested species: rat
CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles.
Ivanova D, Imig C, Camacho M, Reinhold A, Guhathakurta D, Montenegro-Venegas C, Cousin MA, Gundelfinger ED, Rosenmund C, Cooper B, Fejtova A, et al.
Cell reports (2020) 307: 2444-2459.e7. 160 003 ICC; tested species: mouse
Immunoprecipitation of Ribosome-Bound mRNAs from Astrocytic Perisynaptic Processes of the Mouse Hippocampus.
Mazaré N, Oudart M, Cheung G, Boulay AC, Cohen-Salmon M
STAR protocols (2020) 13: 100198. 160 003 ICC; tested species: mouse
Proline-rich transmembrane protein 2 (PRRT2) regulates the actin cytoskeleton during synaptogenesis.
Savino E, Cervigni RI, Povolo M, Stefanetti A, Ferrante D, Valente P, Corradi A, Benfenati F, Guarnieri FC, Valtorta F
Cell death & disease (2020) 1110: 856. 160 003 ICC; tested species: mouse
Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs. isogenic control.
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, Ambasudhan R, Talantova M, Lipton SA
eLife (2019) 8: . 160 003 ICC; tested species: human
Differential Properties of the Synaptogenic Activities of the Neurexin Ligands Neuroligin1 and LRRTM2.
Dagar S, Gottmann K
Frontiers in molecular neuroscience (2019) 12: 269. 160 003 ICC; tested species: mouse
Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice.
Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, Troutman TD, Abe Y, Stender J, Lee D, Wang S, Voytek B, et al.
Translational psychiatry (2019) 91: 24. 160 003 ICC; tested species: mouse
Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA, Zhou B, Nabet AM, Wernig M, Südhof TC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) 3937: 7408-7427. 160 003 ICC; tested species: human
Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses.
Iannielli A, Ugolini GS, Cordiglieri C, Bido S, Rubio A, Colasante G, Valtorta M, Cabassi T, Rasponi M, Broccoli V
Cell reports (2019) 2913: 4646-4656.e4. 160 003 ICC; tested species: human
Glutaredoxin1 diminishes Aβ mediated oxidation of F-actin and reverses cognitive deficits in an Alzheimer's disease mouse model.
Kommaddi RP, Tomar DS, Karunakaran S, Bapat D, Nanguneri S, Ray A, Schneider BL, Nair D, Ravindranath V
Antioxidants & redox signaling (2019) : . 160 003 ICC; tested species: mouse
Intracellular Zn2+ transients modulate global gene expression in dissociated rat hippocampal neurons.
Sanford L, Carpenter MC, Palmer AE
Scientific reports (2019) 91: 9411. 160 003 ICC; tested species: rat
A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in mammalian brain neurons.
Dong JX, Lee Y, Kirmiz M, Palacio S, Dumitras C, Moreno CM, Sando R, Santana LF, Südhof TC, Gong B, Murray KD, et al.
eLife (2019) 8: . 160 003 ICC; tested species: mouse
A Method to Visualize the Nanoscopic Morphology of Astrocytes In Vitro and In Situ.
Heller JP, Rusakov DA
Methods in molecular biology (Clifton, N.J.) (2019) 1938: 69-84. 160 003 ICC; tested species: rat
Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters.
Trotter JH, Hao J, Maxeiner S, Tsetsenis T, Liu Z, Zhuang X, Südhof TC
The Journal of cell biology (2019) : . 160 003 ICC; tested species: mouse
A practical guide to optimization in X10 expansion microscopy.
Truckenbrodt S, Sommer C, Rizzoli SO, Danzl JG
Nature protocols (2019) : . 160 003 ICC; tested species: rat
Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons.
Pennucci R, Gucciardi I, de Curtis I
PloS one (2019) 148: e0220496. 160 003 ICC; tested species: mouse
Bassoon Controls Presynaptic Autophagy through Atg5.
Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC
Neuron (2018) 973: 727. 160 003 ICC; tested species: mouse
Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease.
Kommaddi RP, Das D, Karunakaran S, Nanguneri S, Bapat D, Ray A, Shaw E, Bennett DA, Nair D, Ravindranath V
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 385: 1085-1099. 160 003 ICC; tested species: mouse
Mapping molecular assemblies with fluorescence microscopy and object-based spatial statistics.
Lagache T, Grassart A, Dallongeville S, Faklaris O, Sauvonnet N, Dufour A, Danglot L, Olivo-Marin JC
Nature communications (2018) 91: 698. 160 003 ICC; tested species: mouse
PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin.
Fiuza M, Rostosky CM, Parkinson GT, Bygrave AM, Halemani N, Baptista M, Milosevic I, Hanley JG
The Journal of cell biology (2017) 21610: 3323-3338. 160 003 ICC; tested species: rat
Bassoon Controls Presynaptic Autophagy through Atg5.
Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC
Neuron (2017) 934: 897-913.e7. 160 003 ICC; tested species: mouse
The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn.
Abraira VE, Kuehn ED, Chirila AM, Springel MW, Toliver AA, Zimmerman AL, Orefice LL, Boyle KA, Bai L, Song BJ, Bashista KA, et al.
Cell (2017) 1681-2: 295-310.e19. 160 003 ICC; tested species: mouse
RNA localization is a key determinant of neurite-enriched proteome.
Zappulo A, van den Bruck D, Ciolli Mattioli C, Franke V, Imami K, McShane E, Moreno-Estelles M, Calviello L, Filipchyk A, Peguero-Sanchez E, Müller T, et al.
Nature communications (2017) 81: 583. 160 003 ICC; tested species: mouse
Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.
Altmüller F, Pothula S, Annamneedi A, Nakhaei-Rad S, Montenegro-Venegas C, Pina-Fernández E, Marini C, Santos M, Schanze D, Montag D, Ahmadian MR, et al.
PLoS genetics (2017) 133: e1006684. 160 003 ICC
Neuronal activity controls transsynaptic geometry.
Glebov OO, Cox S, Humphreys L, Burrone J
Scientific reports (2016) 6: 22703. 160 003 ICC
Activity-Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway.
Sheehan P, Zhu M, Beskow A, Vollmer C, Waites CL
The Journal of neuroscience : the official journal of the Society for Neuroscience (2016) 3633: 8668-86. 160 003 ICC; tested species: rat
Multicolour Multilevel STED nanoscopy of Actin/Spectrin Organization at Synapses.
Sidenstein SC, D'Este E, Böhm MJ, Danzl JG, Belov VN, Hell SW
Scientific reports (2016) 6: 26725. 160 003 ICC
Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.
Ivanova D, Dirks A, Montenegro-Venegas C, Schöne C, Altrock WD, Marini C, Frischknecht R, Schanze D, Zenker M, Gundelfinger ED, Fejtova A, et al.
The EMBO journal (2015) 348: 1056-77. 160 003 ICC
STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs.
Garcia-Alvarez G, Lu B, Yap KA, Wong LC, Thevathasan JV, Lim L, Ji F, Tan KW, Mancuso JJ, Tang W, Poon SY, et al.
Molecular biology of the cell (2015) 266: 1141-59. 160 003 ICC
Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains.
Perez de Arce K, Schrod N, Metzbower SWR, Allgeyer E, Kong GK, Tang AH, Krupp AJ, Stein V, Liu X, Bewersdorf J, Blanpied TA, et al.
Neuron (2015) 886: 1165-1172. 160 003 ICC; tested species: rat
High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons.
Andreska T, Aufmkolk S, Sauer M, Blum R
Frontiers in cellular neuroscience (2014) 8: 107. 160 003 ICC; tested species: mouse
Glucocorticoid-related molecular signaling pathways regulating hippocampal neurogenesis.
Anacker C, Cattaneo A, Luoni A, Musaelyan K, Zunszain PA, Milanesi E, Rybka J, Berry A, Cirulli F, Thuret S, Price J, et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2013) 385: 872-83. 160 003 ICC; tested species: human
Activity-dependent regulation of the sumoylation machinery in rat hippocampal neurons.
Loriol C, Khayachi A, Poupon G, Gwizdek C, Martin S
Biology of the cell (2013) 1051: 30-45. 160 003 ICC; tested species: rat
mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.
Wentzel C, Sommer JE, Nair R, Stiefvater A, Sibarita JB, Scheiffele P
Neuron (2013) 786: 1012-23. 160 003 ICC; tested species: mouse
Effects of erythropoietin in murine-induced pluripotent cell-derived panneural progenitor cells.
Offen N, Flemming J, Kamawal H, Ahmad R, Wolber W, Geis C, Zaehres H, Schöler HR, Ehrenreich H, Müller AM, Sirén AL, et al.
Molecular medicine (Cambridge, Mass.) (2013) 19: 399-408. 160 003 ICC; tested species: mouse
Developmental regulation and spatiotemporal redistribution of the sumoylation machinery in the rat central nervous system.
Loriol C, Parisot J, Poupon G, Gwizdek C, Martin S
PloS one (2012) 73: e33757. 160 003 ICC; tested species: rat
Piccolo regulates the dynamic assembly of presynaptic F-actin.
Waites CL, Leal-Ortiz SA, Andlauer TF, Sigrist SJ, Garner CC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3140: 14250-63. 160 003 ICC; tested species: mouse
Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation.
Grabrucker AM, Knight MJ, Proepper C, Bockmann J, Joubert M, Rowan M, Nienhaus GU, Garner CC, Bowie JU, Kreutz MR, Gundelfinger ED, et al.
The EMBO journal (2011) 303: 569-81. 160 003 ICC; tested species: rat
[Artificial urinary sphincter in the treatment of neurogenic bladder in children].
Guys JM, Faure F, Chiapello A, Monfort G
Chirurgie pediatrique (1988) 294: 178-80. 160 003 ICC, IHC; tested species: rat
Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
Monsorno K, Ginggen K, Ivanov A, Buckinx A, Lalive AL, Tchenio A, Benson S, Vendrell M, D'Alessandro A, Beule D, Pellerin L, et al.
Nature communications (2023) 141: 5749. 160 003 WB, IHC; tested species: mouse
The human milk component myo-inositol promotes neuronal connectivity.
Paquette AF, Carbone BE, Vogel S, Israel E, Maria SD, Patil NP, Sah S, Chowdhury D, Kondratiuk I, Labhart B, Morrow AL, et al.
Proceedings of the National Academy of Sciences of the United States of America (2023) 12030: e2221413120. 160 003 ICC, IHC; tested species: human,rat
Stress induces behavioral abnormalities by increasing expression of phagocytic receptor, MERTK, in astrocytes to promote synapse phagocytosis.
Byun YG, Kim NS, Kim G, Jeon YS, Choi JB, Park CW, Kim K, Jang H, Kim J, Kim E, Han YM, et al.
Immunity (2023) : . 160 003 IHC; tested species: mouse
Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging.
Britton R, Wasley T, Harish R, Holz C, Hall J, Yee DC, Melton Witt J, Booth EA, Braithwaite S, Czirr E, Kerrisk Campbell M, et al.
eNeuro (2023) 106: . 160 003 IHC; tested species: mouse
P2Y6 receptor-dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging.
Dundee JM, Puigdellívol M, Butler R, Cockram TOJ, Brown GC
Aging cell (2023) 222: e13761. 160 003 IHC; tested species: mouse
Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.
de Arce KP, Ribic A, Chowdhury D, Watters K, Thompson GJ, Sanganahalli BG, Lippard ETC, Rohlmann A, Strittmatter SM, Missler M, Hyder F, et al.
Nature communications (2023) 141: 459. 160 003 IHC; tested species: mouse
Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain.
Yousefpour N, Locke S, Deamond H, Wang C, Marques L, St-Louis M, Ouellette J, Khoutorsky A, De Koninck Y, Ribeiro-da-Silva A
Cell reports (2023) 421: 112010. 160 003 IHC; tested species: mouse
Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands.
Zhang X, Lin PY, Liakath-Ali K, Südhof TC
Nature communications (2022) 131: 2297. 160 003 IHC; tested species: mouse
MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea.
Ikäheimo K, Herranen A, Iivanainen V, Lankinen T, Aarnisalo AA, Sivonen V, Patel KA, Demir K, Saarma M, Lindahl M, Pirvola U, et al.
Life science alliance (2022) 52: . 160 003 IHC; tested species: mouse
Mild Traumatic Brain Injury-Induced Disruption of the Blood-Brain Barrier Triggers an Atypical Neuronal Response.
Munoz-Ballester C, Mahmutovic D, Rafiqzad Y, Korot A, Robel S
Frontiers in cellular neuroscience (2022) 16: 821885. 160 003 IHC; tested species: mouse
Versatile, do-it-yourself, low-cost spinning disk confocal microscope.
Halpern AR, Lee MY, Howard MD, Woodworth MA, Nicovich PR, Vaughan JC
Biomedical optics express (2022) 132: 1102-1120. 160 003 IHC; tested species: mouse
Hippocampal Excitatory Synaptic Transmission and Plasticity Are Differentially Altered during Postnatal Development by Loss of the X-Linked Intellectual Disability Protein Oligophrenin-1.
Cresto N, Lebrun N, Dumont F, Letourneur F, Billuart P, Rouach N
Cells (2022) 119: . 160 003 IHC; tested species: mouse
Microglial control of neuronal development via somatic purinergic junctions.
Cserép C, Schwarcz AD, Pósfai B, László ZI, Kellermayer A, Környei Z, Kisfali M, Nyerges M, Lele Z, Katona I, Ádám Dénes , et al.
Cell reports (2022) 4012: 111369. 160 003 IHC; tested species: mouse
Microglia maintain the normal structure and function of the hippocampal astrocyte network.
Du Y, Brennan FH, Popovich PG, Zhou M
Glia (2022) 707: 1359-1379. 160 003 IHC; tested species: mouse
Endolymphatic Hydrops is a Marker of Synaptopathy Following Traumatic Noise Exposure.
Badash I, Quiñones PM, Oghalai KJ, Wang J, Lui CG, Macias-Escriva F, Applegate BE, Oghalai JS
Frontiers in cell and developmental biology (2021) 9: 747870. 160 003 IHC; tested species: mouse
Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.
Szebényi K, Wenger LMD, Sun Y, Dunn AWE, Limegrover CA, Gibbons GM, Conci E, Paulsen O, Mierau SB, Balmus G, Lakatos A, et al.
Nature neuroscience (2021) 2411: 1542-1554. 160 003 IHC; tested species: human
Acute post-injury blockade of α2δ-1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury.
Brennan FH, Noble BT, Wang Y, Guan Z, Davis H, Mo X, Harris C, Eroglu C, Ferguson AR, Popovich PG
Cell reports (2021) 344: 108667. 160 003 IHC; tested species: mouse
Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson's Disease.
Veys L, Devroye J, Lefevere E, Cools L, Vandenabeele M, De Groef L
Frontiers in neuroscience (2021) 15: 726476. 160 003 IHC; tested species: mouse
Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution.
Hao X, Allgeyer ES, Lee DR, Antonello J, Watters K, Gerdes JA, Schroeder LK, Bottanelli F, Zhao J, Kidd P, Lessard MD, et al.
Nature methods (2021) 186: 688-693. 160 003 IHC; tested species: mouse
Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.
Ding X, Wang J, Huang M, Chen Z, Liu J, Zhang Q, Zhang C, Xiang Y, Zen K, Li L
Nature communications (2021) 121: 2030. 160 003 IHC; tested species: mouse
Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.
Yilmaz M, Yalcin E, Presumey J, Aw E, Ma M, Whelan CW, Stevens B, McCarroll SA, Carroll MC
Nature neuroscience (2021) 242: 214-224. 160 003 WB, IHC; tested species: mouse
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia.
Henneberger C, Bard L, Panatier A, Reynolds JP, Kopach O, Medvedev NI, Minge D, Herde MK, Anders S, Kraev I, Heller JP, et al.
Neuron (2020) : . 160 003 IHC; tested species: mouse
Microglia monitor and protect neuronal function through specialized somatic purinergic junctions.
Cserép C, Pósfai B, Lénárt N, Fekete R, László ZI, Lele Z, Orsolits B, Molnár G, Heindl S, Schwarcz AD, Ujvári K, et al.
Science (New York, N.Y.) (2020) 3676477: 528-537. 160 003 IHC; tested species: mouse
Protocol for BATTLE-1EX: A High-Resolution Imaging Method to Visualize Whole Synaptic Structures and their Components in the Nervous System.
Inoue A, Kobayashi T, Hirai H, Kanaya N, Kohara K
STAR protocols (2020) 13: 100166. 160 003 IHC; tested species: mouse
REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis.
Griffin P, Sheehan PW, Dimitry JM, Guo C, Kanan MF, Lee J, Zhang J, Musiek ES
eLife (2020) 9: . 160 003 IHC; tested species: mouse
Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3.
Rodriguez-Jimenez FJ, Vilches A, Perez-Arago MA, Clemente E, Roman R, Leal J, Castro AA, Fustero S, Moreno-Manzano V, Jendelova P, Stojkovic M, et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics (2020) : . 160 003 IHC; tested species: mouse
Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning.
Mazaré N, Oudart M, Moulard J, Cheung G, Tortuyaux R, Mailly P, Mazaud D, Bemelmans AP, Boulay AC, Blugeon C, Jourdren L, et al.
Cell reports (2020) 328: 108076. 160 003 IHC; tested species: mouse
Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model.
van Olst L, Verhaege D, Franssen M, Kamermans A, Roucourt B, Carmans S, Ytebrouck E, van der Pol SMA, Wever D, Popovic M, Vandenbroucke RE, et al.
Neurobiology of aging (2020) 89: 89-98. 160 003 IHC; tested species: mouse
Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum.
Zhang RS, Liakath-Ali K, Südhof TC
eLife (2020) 9: . 160 003 WB, IHC; tested species: mouse
Functional Synaptic Architecture of Callosal Inputs in Mouse Primary Visual Cortex.
Lee KS, Vandemark K, Mezey D, Shultz N, Fitzpatrick D
Neuron (2019) 1013: 421-428.e5. 160 003 IHC; tested species: mouse
Scalable and Isotropic Expansion of Tissues with Simply Tunable Expansion Ratio.
Park HE, Choi D, Park JS, Sim C, Park S, Kang S, Yim H, Lee M, Kim J, Pac J, Rhee K, et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2019) 622: 1901673. 160 003 IHC; tested species: mouse
Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution.
Chakraborty T, Driscoll MK, Jeffery E, Murphy MM, Roudot P, Chang BJ, Vora S, Wong WM, Nielson CD, Zhang H, Zhemkov V, et al.
Nature methods (2019) 1611: 1109-1113. 160 003 IHC; tested species: mouse
Combining super-resolution microscopy with neuronal network recording using magnesium fluoride thin films as cover layer for multi-electrode array technology.
Schmidl L, Schmidl G, Gawlik A, Dellith J, Hübner U, Tympel V, Schmidl F, Plentz J, Geis C, Haselmann H
Scientific reports (2019) 91: 16110. 160 003 IHC; tested species: mouse
Structural and functional connections between the median and the ventrolateral preoptic nucleus.
Walter A, van der Spek L, Hardy E, Bemelmans AP, Rouach N, Rancillac A
Brain structure & function (2019) : . 160 003 IHC; tested species: mouse
Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke.
Liang H, Zhao H, Gleichman A, Machnicki M, Telang S, Tang S, Rshtouni M, Ruddell J, Carmichael ST
Proceedings of the National Academy of Sciences of the United States of America (2019) : . 160 003 IHC; tested species: mouse
Imaging tripartite synapses using super-resolution microscopy.
Heller JP, Odii T, Zheng K, Rusakov DA
Methods (San Diego, Calif.) (2019) : . 160 003 IHC; tested species: mouse
Vaccinia-related kinase 2 plays a critical role in microglia-mediated synapse elimination during neurodevelopment.
Lee J, Lee S, Ryu YJ, Lee D, Kim S, Seo JY, Oh E, Paek SH, Kim SU, Ha CM, Choi SY, et al.
Glia (2019) : . 160 003 IHC; tested species: mouse
Young bone marrow transplantation preserves learning and memory in old mice.
Das MM, Godoy M, Chen S, Moser VA, Avalos P, Roxas KM, Dang I, Yáñez A, Zhang W, Bresee C, Arditi M, et al.
Communications biology (2019) 2: 73. 160 003 IHC; tested species: mouse
Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia.
Wang F, Yang YJ, Yang N, Chen XJ, Huang NX, Zhang J, Wu Y, Liu Z, Gao X, Li T, Pan GQ, et al.
Neuron (2018) 994: 689-701.e5. 160 003 IHC; tested species: mouse
The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse.
Becker L, Schnee ME, Niwa M, Sun W, Maxeiner S, Talaei S, Kachar B, Rutherford MA, Ricci AJ
eLife (2018) 7: . 160 003 IHC
Restorative effects of human neural stem cell grafts on the primate spinal cord.
Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, et al.
Nature medicine (2018) : . 160 003 IHC; tested species: human
CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development.
Lehrman EK, Wilton DK, Litvina EY, Welsh CA, Chang ST, Frouin A, Walker AJ, Heller MD, Umemori H, Chen C, Stevens B, et al.
Neuron (2018) 1001: 120-134.e6. 160 003 IHC; tested species: mouse
Transcriptomic Analysis of Ribosome-Bound mRNA in Cortical Neurites In Vivo.
Ouwenga R, Lake AM, O'Brien D, Mogha A, Dani A, Dougherty JD
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3736: 8688-8705. 160 003 IHC; tested species: mouse
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, et al.
Neuron (2017) 935: 1066-1081.e8. 160 003 IHC; tested species: human,mouse
Iterative expansion microscopy.
Chang JB, Chen F, Yoon YG, Jung EE, Babcock H, Kang JS, Asano S, Suk HJ, Pak N, Tillberg PW, Wassie AT, et al.
Nature methods (2017) 146: 593-599. 160 003 IHC; tested species: mouse
Deletion of the Fractalkine Receptor, CX3CR1, Improves Endogenous Repair, Axon Sprouting, and Synaptogenesis after Spinal Cord Injury in Mice.
Freria CM, Hall JC, Wei P, Guan Z, McTigue DM, Popovich PG
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3713: 3568-3587. 160 003 IHC; tested species: mouse
Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues.
Ku T, Swaney J, Park JY, Albanese A, Murray E, Cho JH, Park YG, Mangena V, Chen J, Chung K
Nature biotechnology (2016) 349: 973-81. 160 003 IHC; tested species: mouse
Hippocampal Homer1 levels influence motivational behavior in an operant conditioning task.
Wagner KV, Häusl AS, Pöhlmann ML, Hartmann J, Labermaier C, Müller MB, Schmidt MV
PloS one (2014) 91: e85975. 160 003 IHC; tested species: mouse
FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.
La Fata G, Gärtner A, Domínguez-Iturza N, Dresselaers T, Dawitz J, Poorthuis RB, Averna M, Himmelreich U, Meredith RM, Achsel T, Dotti CG, et al.
Nature neuroscience (2014) 1712: 1693-700. 160 003 IHC; tested species: mouse
Homer1 mediates acute stress-induced cognitive deficits in the dorsal hippocampus.
Wagner KV, Hartmann J, Mangold K, Wang XD, Labermaier C, Liebl C, Wolf M, Gassen NC, Holsboer F, Rein T, Müller MB, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 339: 3857-64. 160 003 IHC; tested species: mouse
Superresolution imaging of chemical synapses in the brain.
Dani A, Huang B, Bergan J, Dulac C, Zhuang X
Neuron (2010) 685: 843-56. 160 003 IHC; tested species: mouse
Delayed appearance of the scaffolding proteins PSD-95 and Homer-1 at the developing rat calyx of Held synapse.
Soria Van Hoeve JS, Borst JG
The Journal of comparative neurology (2010) 51822: 4581-90. 160 003 IHC; tested species: rat
[Artificial urinary sphincter in the treatment of neurogenic bladder in children].
Guys JM, Faure F, Chiapello A, Monfort G
Chirurgie pediatrique (1988) 294: 178-80. 160 003 ICC, IHC; tested species: rat
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Larsson M, Broman J
eNeuro () 61: . 160 003 IHC; tested species: rat
Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release Sites.
Cserép C, Pósfai B, Schwarcz AD, Dénes Á
eNeuro () 51: . 160 003 IHC; tested species: mouse
Heat denaturation enables multicolor X10-STED microscopy.
Saal KA, Shaib AH, Mougios N, Crzan D, Opazo F, Rizzoli SO
Scientific reports (2023) 131: 5366. 160 003 ExM; tested species: rat
Hippocampal dendritic spines express the RyR3 but not the RyR2 ryanodine receptor isoform.
Vega-Vásquez I, Lobos P, Toledo J, Adasme T, Paula-Lima A, Hidalgo C
Biochemical and biophysical research communications (2022) 633: 96-103. 160 003 ICC, ExM; tested species: rat
Fast DNA-PAINT imaging using a deep neural network.
Narayanasamy KK, Rahm JV, Tourani S, Heilemann M
Nature communications (2022) 131: 5047. 160 003 DNA-PAINT; tested species: rat
Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation.
Tao-Cheng JH, Thein S, Yang Y, Reese TS, Gallant PE
Neuroscience (2014) 266: 80-90. 160 003 WB, EM; tested species: rat
Cat. No.: 160 003
Amount: 50 µg
Price: $465.00
Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
Monsorno K, Ginggen K, Ivanov A, Buckinx A, Lalive AL, Tchenio A, Benson S, Vendrell M, D'Alessandro A, Beule D, Pellerin L, et al.
Nature communications (2023) 141: 5749. 160 003 WB, IHC; tested species: mouse
Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus.
Lloyd BA, Han Y, Roth R, Zhang B, Aoto J
Nature communications (2023) 141: 4706. 160 003 WB; tested species: mouse
Developmental Pb exposure increases AD risk via altered intracellular Ca2+ homeostasis in hiPSC-derived cortical neurons.
Xie J, Wu S, Szadowski H, Min S, Yang Y, Bowman AB, Rochet JC, Freeman JL, Yuan C
The Journal of biological chemistry (2023) : 105023. 160 003 WB, ICC; tested species: human
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity.
Hsieh YC, Negri J, He A, Pearse RV, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL
Molecular neurodegeneration (2022) 171: 61. 160 003 WB, ICC; tested species: human
Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy.
Gozzelino L, Kochlamazashvili G, Baldassari S, Mackintosh AI, Licchetta L, Iovino E, Liu YC, Bennett CA, Bennett MF, Damiano JA, Zsurka G, et al.
Brain : a journal of neurology (2022) 1457: 2313-2331. 160 003 WB; tested species: mouse
Nrg1 haploinsufficiency alters inhibitory cortical circuits.
Navarro-Gonzalez C, Carceller H, Benito Vicente M, Serra I, Navarrete M, Domínguez-Canterla Y, Rodríguez-Prieto Á, González-Manteiga A, Fazzari P
Neurobiology of disease (2021) 157: 105442. 160 003 WB; tested species: mouse
Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice.
Prieto M, Folci A, Poupon G, Schiavi S, Buzzelli V, Pronot M, François U, Pousinha P, Lattuada N, Abelanet S, Castagnola S, et al.
Nature communications (2021) 121: 1557. 160 003 WB, ICC; tested species: mouse
Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.
Yilmaz M, Yalcin E, Presumey J, Aw E, Ma M, Whelan CW, Stevens B, McCarroll SA, Carroll MC
Nature neuroscience (2021) 242: 214-224. 160 003 WB, IHC; tested species: mouse
Proteome dynamics during homeostatic scaling in cultured neurons.
Dörrbaum AR, Alvarez-Castelao B, Nassim-Assir B, Langer JD, Schuman EM
eLife (2020) 9: . 160 003 WB; tested species: rat
Selective disruption of inhibitory synapses leading to neuronal hyperexcitability at an early stage of tau pathogenesis in a mouse model.
Shimojo M, Takuwa H, Takado Y, Tokunaga M, Tsukamoto S, Minatohara K, Ono M, Seki C, Maeda J, Urushihata T, Minamihisamatsu T, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 160 003 WB; tested species: mouse
Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum.
Zhang RS, Liakath-Ali K, Südhof TC
eLife (2020) 9: . 160 003 WB, IHC; tested species: mouse
SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.
Sessa A, Fagnocchi L, Mastrototaro G, Massimino L, Zaghi M, Indrigo M, Cattaneo S, Martini D, Gabellini C, Pucci C, Fasciani A, et al.
Neuron (2019) : . 160 003 WB; tested species: mouse
Fluoxetine Suppresses Glutamate- and GABA-Mediated Neurotransmission by Altering SNARE Complex.
Lazarevic V, Mantas I, Flais I, Svenningsson P
International journal of molecular sciences (2019) 2017: . 160 003 WB; tested species: rat
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer NJ, Ma R, Nakayama L, Monbureau M, Defensor E, Schüle B, Shamloo M, et al.
Acta neuropathologica (2019) : . 160 003 WB; tested species: mouse
Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors.
Cromberg LE, Saez TMM, Otero MG, Tomasella E, Alloatti M, Damianich A, Devoto VP, Ferrario J, Gelman D, Rubinstein M, Falzone TL, et al.
Journal of neurochemistry (2019) : . 160 003 WB; tested species: human
Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study.
Aguayo FI, Tejos-Bravo M, Díaz-Véliz G, Pacheco A, García-Rojo G, Corrales W, Olave FA, Aliaga E, Ulloa JL, Avalos AM, Román-Albasini L, et al.
Frontiers in molecular neuroscience (2018) 11: 283. 160 003 WB; tested species: rat
Homer1a drives homeostatic scaling-down of excitatory synapses during sleep.
Diering GH, Nirujogi RS, Roth RH, Worley PF, Pandey A, Huganir RL
Science (New York, N.Y.) (2017) 3556324: 511-515. 160 003 WB, IP; tested species: mouse
Distinct Defects in Synaptic Differentiation of Neocortical Neurons in Response to Prenatal Valproate Exposure.
Iijima Y, Behr K, Iijima T, Biemans B, Bischofberger J, Scheiffele P
Scientific reports (2016) 6: 27400. 160 003 WB
How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.
Acuna C, Liu X, Südhof TC
Neuron (2016) 914: 792-807. 160 003 WB
Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation.
Tao-Cheng JH, Thein S, Yang Y, Reese TS, Gallant PE
Neuroscience (2014) 266: 80-90. 160 003 WB, EM; tested species: rat
SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.
Iijima T, Wu K, Witte H, Hanno-Iijima Y, Glatter T, Richard S, Scheiffele P
Cell (2011) 1477: 1601-14. 160 003 WB; tested species: mouse
Homer1a drives homeostatic scaling-down of excitatory synapses during sleep.
Diering GH, Nirujogi RS, Roth RH, Worley PF, Pandey A, Huganir RL
Science (New York, N.Y.) (2017) 3556324: 511-515. 160 003 WB, IP; tested species: mouse
The human milk component myo-inositol promotes neuronal connectivity.
Paquette AF, Carbone BE, Vogel S, Israel E, Maria SD, Patil NP, Sah S, Chowdhury D, Kondratiuk I, Labhart B, Morrow AL, et al.
Proceedings of the National Academy of Sciences of the United States of America (2023) 12030: e2221413120. 160 003 ICC, IHC; tested species: human,rat
Developmental Pb exposure increases AD risk via altered intracellular Ca2+ homeostasis in hiPSC-derived cortical neurons.
Xie J, Wu S, Szadowski H, Min S, Yang Y, Bowman AB, Rochet JC, Freeman JL, Yuan C
The Journal of biological chemistry (2023) : 105023. 160 003 WB, ICC; tested species: human
Hippocampal dendritic spines express the RyR3 but not the RyR2 ryanodine receptor isoform.
Vega-Vásquez I, Lobos P, Toledo J, Adasme T, Paula-Lima A, Hidalgo C
Biochemical and biophysical research communications (2022) 633: 96-103. 160 003 ICC, ExM; tested species: rat
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity.
Hsieh YC, Negri J, He A, Pearse RV, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL
Molecular neurodegeneration (2022) 171: 61. 160 003 WB, ICC; tested species: human
Deficiency of protocadherin 9 leads to reduction in positive emotional behaviour.
Uemura M, Furuse T, Yamada I, Kushida T, Abe T, Imai K, Nagao S, Kudoh M, Yoshizawa K, Tamura M, Kiyonari H, et al.
Scientific reports (2022) 121: 11933. 160 003 ICC; tested species: mouse
α-Synuclein induced cholesterol lowering increases tonic and reduces depolarization-evoked synaptic vesicle recycling and glutamate release.
Lazarevic V, Yang Y, Paslawski W, Svenningsson P
NPJ Parkinson's disease (2022) 81: 71. 160 003 ICC; tested species: mouse
A Neuron, Microglia, and Astrocyte Triple Co-culture Model to Study Alzheimer's Disease.
Luchena C, Zuazo-Ibarra J, Valero J, Matute C, Alberdi E, Capetillo-Zarate E
Frontiers in aging neuroscience (2022) 14: 844534. 160 003 ICC; tested species: rat
Long-Term Cultures of Spinal Cord Interneurons.
Vargova I, Kriska J, Kwok JCF, Fawcett JW, Jendelova P
Frontiers in cellular neuroscience (2022) 16: 827628. 160 003 ICC; tested species: mouse
A multimodal 3D neuro-microphysiological system with neurite-trapping microelectrodes.
Molina-Martínez B, Jentsch LV, Ersoy F, van der Moolen M, Donato S, Ness TV, Heutink P, Jones PD, Cesare P
Biofabrication (2022) 142: . 160 003 ICC; tested species: mouse
Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice.
Prieto M, Folci A, Poupon G, Schiavi S, Buzzelli V, Pronot M, François U, Pousinha P, Lattuada N, Abelanet S, Castagnola S, et al.
Nature communications (2021) 121: 1557. 160 003 WB, ICC; tested species: mouse
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.
Kuijpers M, Kochlamazashvili G, Stumpf A, Puchkov D, Swaminathan A, Lucht MT, Krause E, Maritzen T, Schmitz D, Haucke V
Neuron (2021) 1092: 299-313.e9. 160 003 ICC; tested species: mouse
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids.
Trujillo CA, Adams JW, Negraes PD, Carromeu C, Tejwani L, Acab A, Tsuda B, Thomas CA, Sodhi N, Fichter KM, Romero S, et al.
EMBO molecular medicine (2021) 131: e12523. 160 003 ICC; tested species: human
Presynaptic activity and protein turnover are correlated at the single-synapse level.
Jähne S, Mikulasch F, Heuer HGH, Truckenbrodt S, Agüi-Gonzalez P, Grewe K, Vogts A, Rizzoli SO, Priesemann V
Cell reports (2021) 3411: 108841. 160 003 ICC; tested species: rat
TRPV1 Antagonist Prevents Neonatal Sevoflurane-Induced Synaptic Abnormality and Cognitive Impairment in Mice Through Regulating the Src/Cofilin Signaling Pathway.
Liu Y, Yang H, Fu Y, Pan Z, Qiu F, Xu Y, Yang X, Chen Q, Ma D, Liu Z
Frontiers in cell and developmental biology (2021) 9: 684516. 160 003 ICC; tested species: mouse
Latrophilin GPCR signaling mediates synapse formation.
Sando R, Südhof TC
eLife (2021) 10: . 160 003 ICC; tested species: mouse
Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease.
Werneburg S, Jung J, Kunjamma RB, Ha SK, Luciano NJ, Willis CM, Gao G, Biscola NP, Havton LA, Crocker SJ, Popko B, et al.
Immunity (2020) 521: 167-182.e7. 160 003 ICC; tested species: mouse
Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates.
Micali N, Kim SK, Diaz-Bustamante M, Stein-O'Brien G, Seo S, Shin JH, Rash BG, Ma S, Wang Y, Olivares NA, Arellano JI, et al.
Cell reports (2020) 315: 107599. 160 003 ICC; tested species: human
Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development.
Bikbaev A, Ciuraszkiewicz-Wojciech A, Heck J, Klatt O, Freund R, Mitlöhner J, Enrile Lacalle S, Sun M, Repetto D, Frischknecht R, Ablinger C, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) 4025: 4824-4841. 160 003 ICC; tested species: rat
CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles.
Ivanova D, Imig C, Camacho M, Reinhold A, Guhathakurta D, Montenegro-Venegas C, Cousin MA, Gundelfinger ED, Rosenmund C, Cooper B, Fejtova A, et al.
Cell reports (2020) 307: 2444-2459.e7. 160 003 ICC; tested species: mouse
Immunoprecipitation of Ribosome-Bound mRNAs from Astrocytic Perisynaptic Processes of the Mouse Hippocampus.
Mazaré N, Oudart M, Cheung G, Boulay AC, Cohen-Salmon M
STAR protocols (2020) 13: 100198. 160 003 ICC; tested species: mouse
Proline-rich transmembrane protein 2 (PRRT2) regulates the actin cytoskeleton during synaptogenesis.
Savino E, Cervigni RI, Povolo M, Stefanetti A, Ferrante D, Valente P, Corradi A, Benfenati F, Guarnieri FC, Valtorta F
Cell death & disease (2020) 1110: 856. 160 003 ICC; tested species: mouse
Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs. isogenic control.
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, Ambasudhan R, Talantova M, Lipton SA
eLife (2019) 8: . 160 003 ICC; tested species: human
Differential Properties of the Synaptogenic Activities of the Neurexin Ligands Neuroligin1 and LRRTM2.
Dagar S, Gottmann K
Frontiers in molecular neuroscience (2019) 12: 269. 160 003 ICC; tested species: mouse
Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice.
Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, Troutman TD, Abe Y, Stender J, Lee D, Wang S, Voytek B, et al.
Translational psychiatry (2019) 91: 24. 160 003 ICC; tested species: mouse
Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA, Zhou B, Nabet AM, Wernig M, Südhof TC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) 3937: 7408-7427. 160 003 ICC; tested species: human
Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses.
Iannielli A, Ugolini GS, Cordiglieri C, Bido S, Rubio A, Colasante G, Valtorta M, Cabassi T, Rasponi M, Broccoli V
Cell reports (2019) 2913: 4646-4656.e4. 160 003 ICC; tested species: human
Glutaredoxin1 diminishes Aβ mediated oxidation of F-actin and reverses cognitive deficits in an Alzheimer's disease mouse model.
Kommaddi RP, Tomar DS, Karunakaran S, Bapat D, Nanguneri S, Ray A, Schneider BL, Nair D, Ravindranath V
Antioxidants & redox signaling (2019) : . 160 003 ICC; tested species: mouse
Intracellular Zn2+ transients modulate global gene expression in dissociated rat hippocampal neurons.
Sanford L, Carpenter MC, Palmer AE
Scientific reports (2019) 91: 9411. 160 003 ICC; tested species: rat
A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in mammalian brain neurons.
Dong JX, Lee Y, Kirmiz M, Palacio S, Dumitras C, Moreno CM, Sando R, Santana LF, Südhof TC, Gong B, Murray KD, et al.
eLife (2019) 8: . 160 003 ICC; tested species: mouse
A Method to Visualize the Nanoscopic Morphology of Astrocytes In Vitro and In Situ.
Heller JP, Rusakov DA
Methods in molecular biology (Clifton, N.J.) (2019) 1938: 69-84. 160 003 ICC; tested species: rat
Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters.
Trotter JH, Hao J, Maxeiner S, Tsetsenis T, Liu Z, Zhuang X, Südhof TC
The Journal of cell biology (2019) : . 160 003 ICC; tested species: mouse
A practical guide to optimization in X10 expansion microscopy.
Truckenbrodt S, Sommer C, Rizzoli SO, Danzl JG
Nature protocols (2019) : . 160 003 ICC; tested species: rat
Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons.
Pennucci R, Gucciardi I, de Curtis I
PloS one (2019) 148: e0220496. 160 003 ICC; tested species: mouse
Bassoon Controls Presynaptic Autophagy through Atg5.
Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC
Neuron (2018) 973: 727. 160 003 ICC; tested species: mouse
Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease.
Kommaddi RP, Das D, Karunakaran S, Nanguneri S, Bapat D, Ray A, Shaw E, Bennett DA, Nair D, Ravindranath V
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 385: 1085-1099. 160 003 ICC; tested species: mouse
Mapping molecular assemblies with fluorescence microscopy and object-based spatial statistics.
Lagache T, Grassart A, Dallongeville S, Faklaris O, Sauvonnet N, Dufour A, Danglot L, Olivo-Marin JC
Nature communications (2018) 91: 698. 160 003 ICC; tested species: mouse
PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin.
Fiuza M, Rostosky CM, Parkinson GT, Bygrave AM, Halemani N, Baptista M, Milosevic I, Hanley JG
The Journal of cell biology (2017) 21610: 3323-3338. 160 003 ICC; tested species: rat
Bassoon Controls Presynaptic Autophagy through Atg5.
Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC
Neuron (2017) 934: 897-913.e7. 160 003 ICC; tested species: mouse
The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn.
Abraira VE, Kuehn ED, Chirila AM, Springel MW, Toliver AA, Zimmerman AL, Orefice LL, Boyle KA, Bai L, Song BJ, Bashista KA, et al.
Cell (2017) 1681-2: 295-310.e19. 160 003 ICC; tested species: mouse
RNA localization is a key determinant of neurite-enriched proteome.
Zappulo A, van den Bruck D, Ciolli Mattioli C, Franke V, Imami K, McShane E, Moreno-Estelles M, Calviello L, Filipchyk A, Peguero-Sanchez E, Müller T, et al.
Nature communications (2017) 81: 583. 160 003 ICC; tested species: mouse
Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.
Altmüller F, Pothula S, Annamneedi A, Nakhaei-Rad S, Montenegro-Venegas C, Pina-Fernández E, Marini C, Santos M, Schanze D, Montag D, Ahmadian MR, et al.
PLoS genetics (2017) 133: e1006684. 160 003 ICC
Neuronal activity controls transsynaptic geometry.
Glebov OO, Cox S, Humphreys L, Burrone J
Scientific reports (2016) 6: 22703. 160 003 ICC
Activity-Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway.
Sheehan P, Zhu M, Beskow A, Vollmer C, Waites CL
The Journal of neuroscience : the official journal of the Society for Neuroscience (2016) 3633: 8668-86. 160 003 ICC; tested species: rat
Multicolour Multilevel STED nanoscopy of Actin/Spectrin Organization at Synapses.
Sidenstein SC, D'Este E, Böhm MJ, Danzl JG, Belov VN, Hell SW
Scientific reports (2016) 6: 26725. 160 003 ICC
Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.
Ivanova D, Dirks A, Montenegro-Venegas C, Schöne C, Altrock WD, Marini C, Frischknecht R, Schanze D, Zenker M, Gundelfinger ED, Fejtova A, et al.
The EMBO journal (2015) 348: 1056-77. 160 003 ICC
STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs.
Garcia-Alvarez G, Lu B, Yap KA, Wong LC, Thevathasan JV, Lim L, Ji F, Tan KW, Mancuso JJ, Tang W, Poon SY, et al.
Molecular biology of the cell (2015) 266: 1141-59. 160 003 ICC
Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains.
Perez de Arce K, Schrod N, Metzbower SWR, Allgeyer E, Kong GK, Tang AH, Krupp AJ, Stein V, Liu X, Bewersdorf J, Blanpied TA, et al.
Neuron (2015) 886: 1165-1172. 160 003 ICC; tested species: rat
High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons.
Andreska T, Aufmkolk S, Sauer M, Blum R
Frontiers in cellular neuroscience (2014) 8: 107. 160 003 ICC; tested species: mouse
Glucocorticoid-related molecular signaling pathways regulating hippocampal neurogenesis.
Anacker C, Cattaneo A, Luoni A, Musaelyan K, Zunszain PA, Milanesi E, Rybka J, Berry A, Cirulli F, Thuret S, Price J, et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2013) 385: 872-83. 160 003 ICC; tested species: human
Activity-dependent regulation of the sumoylation machinery in rat hippocampal neurons.
Loriol C, Khayachi A, Poupon G, Gwizdek C, Martin S
Biology of the cell (2013) 1051: 30-45. 160 003 ICC; tested species: rat
mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.
Wentzel C, Sommer JE, Nair R, Stiefvater A, Sibarita JB, Scheiffele P
Neuron (2013) 786: 1012-23. 160 003 ICC; tested species: mouse
Effects of erythropoietin in murine-induced pluripotent cell-derived panneural progenitor cells.
Offen N, Flemming J, Kamawal H, Ahmad R, Wolber W, Geis C, Zaehres H, Schöler HR, Ehrenreich H, Müller AM, Sirén AL, et al.
Molecular medicine (Cambridge, Mass.) (2013) 19: 399-408. 160 003 ICC; tested species: mouse
Developmental regulation and spatiotemporal redistribution of the sumoylation machinery in the rat central nervous system.
Loriol C, Parisot J, Poupon G, Gwizdek C, Martin S
PloS one (2012) 73: e33757. 160 003 ICC; tested species: rat
Piccolo regulates the dynamic assembly of presynaptic F-actin.
Waites CL, Leal-Ortiz SA, Andlauer TF, Sigrist SJ, Garner CC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3140: 14250-63. 160 003 ICC; tested species: mouse
Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation.
Grabrucker AM, Knight MJ, Proepper C, Bockmann J, Joubert M, Rowan M, Nienhaus GU, Garner CC, Bowie JU, Kreutz MR, Gundelfinger ED, et al.
The EMBO journal (2011) 303: 569-81. 160 003 ICC; tested species: rat
[Artificial urinary sphincter in the treatment of neurogenic bladder in children].
Guys JM, Faure F, Chiapello A, Monfort G
Chirurgie pediatrique (1988) 294: 178-80. 160 003 ICC, IHC; tested species: rat
Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
Monsorno K, Ginggen K, Ivanov A, Buckinx A, Lalive AL, Tchenio A, Benson S, Vendrell M, D'Alessandro A, Beule D, Pellerin L, et al.
Nature communications (2023) 141: 5749. 160 003 WB, IHC; tested species: mouse
The human milk component myo-inositol promotes neuronal connectivity.
Paquette AF, Carbone BE, Vogel S, Israel E, Maria SD, Patil NP, Sah S, Chowdhury D, Kondratiuk I, Labhart B, Morrow AL, et al.
Proceedings of the National Academy of Sciences of the United States of America (2023) 12030: e2221413120. 160 003 ICC, IHC; tested species: human,rat
Stress induces behavioral abnormalities by increasing expression of phagocytic receptor, MERTK, in astrocytes to promote synapse phagocytosis.
Byun YG, Kim NS, Kim G, Jeon YS, Choi JB, Park CW, Kim K, Jang H, Kim J, Kim E, Han YM, et al.
Immunity (2023) : . 160 003 IHC; tested species: mouse
Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging.
Britton R, Wasley T, Harish R, Holz C, Hall J, Yee DC, Melton Witt J, Booth EA, Braithwaite S, Czirr E, Kerrisk Campbell M, et al.
eNeuro (2023) 106: . 160 003 IHC; tested species: mouse
P2Y6 receptor-dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging.
Dundee JM, Puigdellívol M, Butler R, Cockram TOJ, Brown GC
Aging cell (2023) 222: e13761. 160 003 IHC; tested species: mouse
Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.
de Arce KP, Ribic A, Chowdhury D, Watters K, Thompson GJ, Sanganahalli BG, Lippard ETC, Rohlmann A, Strittmatter SM, Missler M, Hyder F, et al.
Nature communications (2023) 141: 459. 160 003 IHC; tested species: mouse
Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain.
Yousefpour N, Locke S, Deamond H, Wang C, Marques L, St-Louis M, Ouellette J, Khoutorsky A, De Koninck Y, Ribeiro-da-Silva A
Cell reports (2023) 421: 112010. 160 003 IHC; tested species: mouse
Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands.
Zhang X, Lin PY, Liakath-Ali K, Südhof TC
Nature communications (2022) 131: 2297. 160 003 IHC; tested species: mouse
MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea.
Ikäheimo K, Herranen A, Iivanainen V, Lankinen T, Aarnisalo AA, Sivonen V, Patel KA, Demir K, Saarma M, Lindahl M, Pirvola U, et al.
Life science alliance (2022) 52: . 160 003 IHC; tested species: mouse
Mild Traumatic Brain Injury-Induced Disruption of the Blood-Brain Barrier Triggers an Atypical Neuronal Response.
Munoz-Ballester C, Mahmutovic D, Rafiqzad Y, Korot A, Robel S
Frontiers in cellular neuroscience (2022) 16: 821885. 160 003 IHC; tested species: mouse
Versatile, do-it-yourself, low-cost spinning disk confocal microscope.
Halpern AR, Lee MY, Howard MD, Woodworth MA, Nicovich PR, Vaughan JC
Biomedical optics express (2022) 132: 1102-1120. 160 003 IHC; tested species: mouse
Hippocampal Excitatory Synaptic Transmission and Plasticity Are Differentially Altered during Postnatal Development by Loss of the X-Linked Intellectual Disability Protein Oligophrenin-1.
Cresto N, Lebrun N, Dumont F, Letourneur F, Billuart P, Rouach N
Cells (2022) 119: . 160 003 IHC; tested species: mouse
Microglial control of neuronal development via somatic purinergic junctions.
Cserép C, Schwarcz AD, Pósfai B, László ZI, Kellermayer A, Környei Z, Kisfali M, Nyerges M, Lele Z, Katona I, Ádám Dénes , et al.
Cell reports (2022) 4012: 111369. 160 003 IHC; tested species: mouse
Microglia maintain the normal structure and function of the hippocampal astrocyte network.
Du Y, Brennan FH, Popovich PG, Zhou M
Glia (2022) 707: 1359-1379. 160 003 IHC; tested species: mouse
Endolymphatic Hydrops is a Marker of Synaptopathy Following Traumatic Noise Exposure.
Badash I, Quiñones PM, Oghalai KJ, Wang J, Lui CG, Macias-Escriva F, Applegate BE, Oghalai JS
Frontiers in cell and developmental biology (2021) 9: 747870. 160 003 IHC; tested species: mouse
Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.
Szebényi K, Wenger LMD, Sun Y, Dunn AWE, Limegrover CA, Gibbons GM, Conci E, Paulsen O, Mierau SB, Balmus G, Lakatos A, et al.
Nature neuroscience (2021) 2411: 1542-1554. 160 003 IHC; tested species: human
Acute post-injury blockade of α2δ-1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury.
Brennan FH, Noble BT, Wang Y, Guan Z, Davis H, Mo X, Harris C, Eroglu C, Ferguson AR, Popovich PG
Cell reports (2021) 344: 108667. 160 003 IHC; tested species: mouse
Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson's Disease.
Veys L, Devroye J, Lefevere E, Cools L, Vandenabeele M, De Groef L
Frontiers in neuroscience (2021) 15: 726476. 160 003 IHC; tested species: mouse
Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution.
Hao X, Allgeyer ES, Lee DR, Antonello J, Watters K, Gerdes JA, Schroeder LK, Bottanelli F, Zhao J, Kidd P, Lessard MD, et al.
Nature methods (2021) 186: 688-693. 160 003 IHC; tested species: mouse
Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.
Ding X, Wang J, Huang M, Chen Z, Liu J, Zhang Q, Zhang C, Xiang Y, Zen K, Li L
Nature communications (2021) 121: 2030. 160 003 IHC; tested species: mouse
Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.
Yilmaz M, Yalcin E, Presumey J, Aw E, Ma M, Whelan CW, Stevens B, McCarroll SA, Carroll MC
Nature neuroscience (2021) 242: 214-224. 160 003 WB, IHC; tested species: mouse
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia.
Henneberger C, Bard L, Panatier A, Reynolds JP, Kopach O, Medvedev NI, Minge D, Herde MK, Anders S, Kraev I, Heller JP, et al.
Neuron (2020) : . 160 003 IHC; tested species: mouse
Microglia monitor and protect neuronal function through specialized somatic purinergic junctions.
Cserép C, Pósfai B, Lénárt N, Fekete R, László ZI, Lele Z, Orsolits B, Molnár G, Heindl S, Schwarcz AD, Ujvári K, et al.
Science (New York, N.Y.) (2020) 3676477: 528-537. 160 003 IHC; tested species: mouse
Protocol for BATTLE-1EX: A High-Resolution Imaging Method to Visualize Whole Synaptic Structures and their Components in the Nervous System.
Inoue A, Kobayashi T, Hirai H, Kanaya N, Kohara K
STAR protocols (2020) 13: 100166. 160 003 IHC; tested species: mouse
REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis.
Griffin P, Sheehan PW, Dimitry JM, Guo C, Kanan MF, Lee J, Zhang J, Musiek ES
eLife (2020) 9: . 160 003 IHC; tested species: mouse
Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3.
Rodriguez-Jimenez FJ, Vilches A, Perez-Arago MA, Clemente E, Roman R, Leal J, Castro AA, Fustero S, Moreno-Manzano V, Jendelova P, Stojkovic M, et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics (2020) : . 160 003 IHC; tested species: mouse
Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning.
Mazaré N, Oudart M, Moulard J, Cheung G, Tortuyaux R, Mailly P, Mazaud D, Bemelmans AP, Boulay AC, Blugeon C, Jourdren L, et al.
Cell reports (2020) 328: 108076. 160 003 IHC; tested species: mouse
Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model.
van Olst L, Verhaege D, Franssen M, Kamermans A, Roucourt B, Carmans S, Ytebrouck E, van der Pol SMA, Wever D, Popovic M, Vandenbroucke RE, et al.
Neurobiology of aging (2020) 89: 89-98. 160 003 IHC; tested species: mouse
Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum.
Zhang RS, Liakath-Ali K, Südhof TC
eLife (2020) 9: . 160 003 WB, IHC; tested species: mouse
Functional Synaptic Architecture of Callosal Inputs in Mouse Primary Visual Cortex.
Lee KS, Vandemark K, Mezey D, Shultz N, Fitzpatrick D
Neuron (2019) 1013: 421-428.e5. 160 003 IHC; tested species: mouse
Scalable and Isotropic Expansion of Tissues with Simply Tunable Expansion Ratio.
Park HE, Choi D, Park JS, Sim C, Park S, Kang S, Yim H, Lee M, Kim J, Pac J, Rhee K, et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2019) 622: 1901673. 160 003 IHC; tested species: mouse
Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution.
Chakraborty T, Driscoll MK, Jeffery E, Murphy MM, Roudot P, Chang BJ, Vora S, Wong WM, Nielson CD, Zhang H, Zhemkov V, et al.
Nature methods (2019) 1611: 1109-1113. 160 003 IHC; tested species: mouse
Combining super-resolution microscopy with neuronal network recording using magnesium fluoride thin films as cover layer for multi-electrode array technology.
Schmidl L, Schmidl G, Gawlik A, Dellith J, Hübner U, Tympel V, Schmidl F, Plentz J, Geis C, Haselmann H
Scientific reports (2019) 91: 16110. 160 003 IHC; tested species: mouse
Structural and functional connections between the median and the ventrolateral preoptic nucleus.
Walter A, van der Spek L, Hardy E, Bemelmans AP, Rouach N, Rancillac A
Brain structure & function (2019) : . 160 003 IHC; tested species: mouse
Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke.
Liang H, Zhao H, Gleichman A, Machnicki M, Telang S, Tang S, Rshtouni M, Ruddell J, Carmichael ST
Proceedings of the National Academy of Sciences of the United States of America (2019) : . 160 003 IHC; tested species: mouse
Imaging tripartite synapses using super-resolution microscopy.
Heller JP, Odii T, Zheng K, Rusakov DA
Methods (San Diego, Calif.) (2019) : . 160 003 IHC; tested species: mouse
Vaccinia-related kinase 2 plays a critical role in microglia-mediated synapse elimination during neurodevelopment.
Lee J, Lee S, Ryu YJ, Lee D, Kim S, Seo JY, Oh E, Paek SH, Kim SU, Ha CM, Choi SY, et al.
Glia (2019) : . 160 003 IHC; tested species: mouse
Young bone marrow transplantation preserves learning and memory in old mice.
Das MM, Godoy M, Chen S, Moser VA, Avalos P, Roxas KM, Dang I, Yáñez A, Zhang W, Bresee C, Arditi M, et al.
Communications biology (2019) 2: 73. 160 003 IHC; tested species: mouse
Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia.
Wang F, Yang YJ, Yang N, Chen XJ, Huang NX, Zhang J, Wu Y, Liu Z, Gao X, Li T, Pan GQ, et al.
Neuron (2018) 994: 689-701.e5. 160 003 IHC; tested species: mouse
The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse.
Becker L, Schnee ME, Niwa M, Sun W, Maxeiner S, Talaei S, Kachar B, Rutherford MA, Ricci AJ
eLife (2018) 7: . 160 003 IHC
Restorative effects of human neural stem cell grafts on the primate spinal cord.
Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, et al.
Nature medicine (2018) : . 160 003 IHC; tested species: human
CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development.
Lehrman EK, Wilton DK, Litvina EY, Welsh CA, Chang ST, Frouin A, Walker AJ, Heller MD, Umemori H, Chen C, Stevens B, et al.
Neuron (2018) 1001: 120-134.e6. 160 003 IHC; tested species: mouse
Transcriptomic Analysis of Ribosome-Bound mRNA in Cortical Neurites In Vivo.
Ouwenga R, Lake AM, O'Brien D, Mogha A, Dani A, Dougherty JD
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3736: 8688-8705. 160 003 IHC; tested species: mouse
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, et al.
Neuron (2017) 935: 1066-1081.e8. 160 003 IHC; tested species: human,mouse
Iterative expansion microscopy.
Chang JB, Chen F, Yoon YG, Jung EE, Babcock H, Kang JS, Asano S, Suk HJ, Pak N, Tillberg PW, Wassie AT, et al.
Nature methods (2017) 146: 593-599. 160 003 IHC; tested species: mouse
Deletion of the Fractalkine Receptor, CX3CR1, Improves Endogenous Repair, Axon Sprouting, and Synaptogenesis after Spinal Cord Injury in Mice.
Freria CM, Hall JC, Wei P, Guan Z, McTigue DM, Popovich PG
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3713: 3568-3587. 160 003 IHC; tested species: mouse
Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues.
Ku T, Swaney J, Park JY, Albanese A, Murray E, Cho JH, Park YG, Mangena V, Chen J, Chung K
Nature biotechnology (2016) 349: 973-81. 160 003 IHC; tested species: mouse
Hippocampal Homer1 levels influence motivational behavior in an operant conditioning task.
Wagner KV, Häusl AS, Pöhlmann ML, Hartmann J, Labermaier C, Müller MB, Schmidt MV
PloS one (2014) 91: e85975. 160 003 IHC; tested species: mouse
FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.
La Fata G, Gärtner A, Domínguez-Iturza N, Dresselaers T, Dawitz J, Poorthuis RB, Averna M, Himmelreich U, Meredith RM, Achsel T, Dotti CG, et al.
Nature neuroscience (2014) 1712: 1693-700. 160 003 IHC; tested species: mouse
Homer1 mediates acute stress-induced cognitive deficits in the dorsal hippocampus.
Wagner KV, Hartmann J, Mangold K, Wang XD, Labermaier C, Liebl C, Wolf M, Gassen NC, Holsboer F, Rein T, Müller MB, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 339: 3857-64. 160 003 IHC; tested species: mouse
Superresolution imaging of chemical synapses in the brain.
Dani A, Huang B, Bergan J, Dulac C, Zhuang X
Neuron (2010) 685: 843-56. 160 003 IHC; tested species: mouse
Delayed appearance of the scaffolding proteins PSD-95 and Homer-1 at the developing rat calyx of Held synapse.
Soria Van Hoeve JS, Borst JG
The Journal of comparative neurology (2010) 51822: 4581-90. 160 003 IHC; tested species: rat
[Artificial urinary sphincter in the treatment of neurogenic bladder in children].
Guys JM, Faure F, Chiapello A, Monfort G
Chirurgie pediatrique (1988) 294: 178-80. 160 003 ICC, IHC; tested species: rat
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Larsson M, Broman J
eNeuro () 61: . 160 003 IHC; tested species: rat
Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release Sites.
Cserép C, Pósfai B, Schwarcz AD, Dénes Á
eNeuro () 51: . 160 003 IHC; tested species: mouse
Heat denaturation enables multicolor X10-STED microscopy.
Saal KA, Shaib AH, Mougios N, Crzan D, Opazo F, Rizzoli SO
Scientific reports (2023) 131: 5366. 160 003 ExM; tested species: rat
Hippocampal dendritic spines express the RyR3 but not the RyR2 ryanodine receptor isoform.
Vega-Vásquez I, Lobos P, Toledo J, Adasme T, Paula-Lima A, Hidalgo C
Biochemical and biophysical research communications (2022) 633: 96-103. 160 003 ICC, ExM; tested species: rat
Fast DNA-PAINT imaging using a deep neural network.
Narayanasamy KK, Rahm JV, Tourani S, Heilemann M
Nature communications (2022) 131: 5047. 160 003 DNA-PAINT; tested species: rat
Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation.
Tao-Cheng JH, Thein S, Yang Y, Reese TS, Gallant PE
Neuroscience (2014) 266: 80-90. 160 003 WB, EM; tested species: rat
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Background

Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, homer was suggested to organize distinct signalling domains.
Three isoforms, Homer 1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.
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