Tailor-made Antibodies
and Tools for Life Science
Home|||||||Technical Support|

Homer 3 protein - 160-3P

Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors
control protein
Cat. No.: 160-3P
Amount: 100 µg
Price: $90.00
Cat. No. 160-3P 100 µg lyophilized protein. For reconstitution add 100 µl H2O to get a 1mg/ml solution in MBS. Then aliquot and store at -20°C until use.
Applications
 
Immunogen Recombinant protein corresponding to AA 1 to 177 from rat Homer3 (UniProt Id: Q9Z2X5)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 160 303
Remarks

This control protein consists of the recombinant protein (aa 1 - 177 of rat homer 3) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 160-3p.pdf
Cat. No.: 160-3P
Amount: 100 µg
Price: $90.00
Background

Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, Homer was suggested to organize distinct signalling domains.
Three isoforms, Homer 1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.

Protocols