|Cat. No. 124 202||200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.|
WB: 1 : 1000 (AP staining) gallery
ICC: not recommended (see remarks)
IHC: not recommended
IHC-P/FFPE: not tested yet
|Immunogen||Synthetic peptide corresponding to AA 14 to 26 from rat SAP102 (UniProt Id: Q62936)|
Reacts with: human (Q92796), rat (Q62936), mouse (P70175), hamster.
No signal: zebrafish.
Other species not tested yet.
|Specificity||Specific for SAP 102. K.O.|
|Matching control protein/peptide||124-2P|
ICC: Cat. no. 124 213 is recommended.
SAP 102 (synapse associated protein of 102 kDa, also called DLG 3) belongs to the PSD 95 family containing a modular structure with three PDZ-, one SH3- and a guanylate kinase-like domain. It is a component of postsynaptic densities in central synapses. It is involved in NMDA receptor clustering and immobilization. In vitro, all three PDZ domains in SAP 102 bind the cytoplasmic tail of NR2B.