|Cat. No. 124 213||50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.|
WB: 1 : 1000 (AP staining) gallery
ICC: 1 : 500 gallery
IHC: 1 : 500 gallery
IHC-P/FFPE: not tested yet
|Immunogen||Recombinant protein corresponding to AA 1 to 146 from mouse SAP102 (UniProt Id: P70175)|
Reacts with: rat (Q62936), mouse (P70175).
Other species not tested yet.
|Specificity||Specific for SAP 102. A very faint signal remains visible at 1 : 1000. K.O. PubMed: 30078578|
SAP 102 (synapse associated protein of 102 kDa, also called DLG 3) belongs to the PSD 95 family containing a modular structure with three PDZ-, one SH3- and a guanylate kinase-like domain. It is a component of postsynaptic densities in central synapses. It is involved in NMDA receptor clustering and immobilization. In vitro, all three PDZ domains in SAP 102 bind the cytoplasmic tail of NR2B.