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PSD95 antibody PDZ domain - 124 012

PSD 95 is a component of postsynaptic densities in central synapses
Rabbit polyclonal antiserum
Cat. No.: 124 012
Amount: 200 µl
Price: $350.00
Cat. No. 124 012 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications
 
WB: 1 : 1000 up to 1 : 10000 (AP staining) gallery  
IP: yes
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 68 to 251 from mouse PSD95 (UniProt Id: Q62108)
Reactivity Reacts with: rat (P31016), mouse (Q62108).
Other species not tested yet.
Specificity Specific for PSD 95 with weak cross-reactivity to SAP 102 K.O.
Matching control protein/peptide 124-01P
Data sheet 124_012.pdf

References for PSD95 - 124 012

Parvalbumin-producing striatal interneurons receive excitatory inputs onto proximal dendrites from the motor thalamus in male mice.
Nakano Y, Karube F, Hirai Y, Kobayashi K, Hioki H, Okamoto S, Kameda H, Fujiyama F
Journal of neuroscience research (2018) : . 124 012 IHC; tested species: mouse
Cat. No.: 124 012
Amount: 200 µl
Price: $350.00
Parvalbumin-producing striatal interneurons receive excitatory inputs onto proximal dendrites from the motor thalamus in male mice.
Nakano Y, Karube F, Hirai Y, Kobayashi K, Hioki H, Okamoto S, Kameda H, Fujiyama F
Journal of neuroscience research (2018) : . 124 012 IHC; tested species: mouse
Background

PSD95 (postsynaptic density protein 95 kDa, also called SAP 90: synapse associated protein of 90 kDa and DLG 4) is a component of postsynaptic densities in central synapses. It contains three PDZ domains. The first and second PDZ domain localizes NMDA receptors and K+ channels to synapses, the third binds to neuroligins which are neuronal cell adhesion molecules that interact with β-neurexins and form intercellular junctions. Thus different PDZ domains of PSD 95 might be specialized for distinct functions. Read more: PSD95 single domain antibody