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Syntaxin 4 antibody - 110 043

Syntaxin4 is an ubiquitous plasma membrane protein involved in fusion of vesicles with the plasma membrane
Polyclonal rabbit purified antibody
Cat. No.: 110 043
Amount: 50 µg
Price: $450.00
Cat. No. 110 043 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: yes
ICC: 1 : 100 gallery  
IHC: not tested yet
IHC-P/FFPE: 1 : 500
EM: yes
Immunogen Recombinant protein corresponding to AA 1 to 273 from rat Syntaxin4 (UniProt Id: Q08850)
Reactivity Reacts with: human (Q12846), rat (Q08850), mouse (P70452), hamster.
Other species not tested yet.
Specificity Specific for syntaxin 4. K.D. PubMed: 31128202
Matching control protein/peptide 110-4P
Data sheet 110_043.pdf

References for Syntaxin 4 - 110 043

Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 043 WB, IP, ICC; tested species: mouse
SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.
Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, et al.
JCI insight (2020) 53: . 110 043 WB; tested species: human,mouse
Role of SNAREs in the Atopic Dermatitis-related Cytokine Secretion and Skin-Nerve Communication.
Meng J, Wang J, Buddenkotte J, Buhl T, Steinhoff M
The Journal of investigative dermatology (2019) : . 110 043 WB; KD verified; tested species: human
Syntaxin 4 is concentrated on plasma membrane of astrocytes.
Tao-Cheng JH, Pham A, Yang Y, Winters CA, Gallant PE, Reese TS
Neuroscience (2015) 286: 264-71. 110 043 WB, EM
Blockade of the SNARE protein syntaxin 1 inhibits glioblastoma tumor growth.
Ulloa F, Gonzàlez-Juncà A, Meffre D, Barrecheguren PJ, Martínez-Mármol R, Pazos I, Olivé N, Cotrufo T, Seoane J, Soriano E
PloS one (2015) 103: e0119707. 110 043 WB
The major myelin-resident protein PLP is transported to myelin membranes via a transcytotic mechanism: involvement of sulfatide.
Baron W, Ozgen H, Klunder B, de Jonge JC, Nomden A, Plat A, Trifilieff E, de Vries H, Hoekstra D
Molecular and cellular biology (2015) 351: 288-302. 110 043 WB
S-acylation of the Insulin-Responsive Aminopeptidase (IRAP): Quantitative analysis and Identification of Modified Cysteines.
Werno MW, Chamberlain LH
Scientific reports (2015) 5: 12413. 110 043 WB
Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 043 WB, IP, ICC; tested species: mouse
Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 043 WB, IP, ICC; tested species: mouse
Choroid plexus epithelial cells express the adhesion protein P-cadherin at cell-cell contacts and syntaxin-4 in the luminal membrane domain.
Christensen IB, Mogensen EN, Damkier HH, Praetorius J
American journal of physiology. Cell physiology (2018) 3145: C519-C533. 110 043 IHC-P; tested species: mouse
Syntaxin 4 is concentrated on plasma membrane of astrocytes.
Tao-Cheng JH, Pham A, Yang Y, Winters CA, Gallant PE, Reese TS
Neuroscience (2015) 286: 264-71. 110 043 WB, EM
Cat. No.: 110 043
Quantity: 50 µg
Price: $450.00
Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 043 WB, IP, ICC; tested species: mouse
SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.
Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, et al.
JCI insight (2020) 53: . 110 043 WB; tested species: human,mouse
Role of SNAREs in the Atopic Dermatitis-related Cytokine Secretion and Skin-Nerve Communication.
Meng J, Wang J, Buddenkotte J, Buhl T, Steinhoff M
The Journal of investigative dermatology (2019) : . 110 043 WB; KD verified; tested species: human
Syntaxin 4 is concentrated on plasma membrane of astrocytes.
Tao-Cheng JH, Pham A, Yang Y, Winters CA, Gallant PE, Reese TS
Neuroscience (2015) 286: 264-71. 110 043 WB, EM
Blockade of the SNARE protein syntaxin 1 inhibits glioblastoma tumor growth.
Ulloa F, Gonzàlez-Juncà A, Meffre D, Barrecheguren PJ, Martínez-Mármol R, Pazos I, Olivé N, Cotrufo T, Seoane J, Soriano E
PloS one (2015) 103: e0119707. 110 043 WB
The major myelin-resident protein PLP is transported to myelin membranes via a transcytotic mechanism: involvement of sulfatide.
Baron W, Ozgen H, Klunder B, de Jonge JC, Nomden A, Plat A, Trifilieff E, de Vries H, Hoekstra D
Molecular and cellular biology (2015) 351: 288-302. 110 043 WB
S-acylation of the Insulin-Responsive Aminopeptidase (IRAP): Quantitative analysis and Identification of Modified Cysteines.
Werno MW, Chamberlain LH
Scientific reports (2015) 5: 12413. 110 043 WB
Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 043 WB, IP, ICC; tested species: mouse
Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 043 WB, IP, ICC; tested species: mouse
Choroid plexus epithelial cells express the adhesion protein P-cadherin at cell-cell contacts and syntaxin-4 in the luminal membrane domain.
Christensen IB, Mogensen EN, Damkier HH, Praetorius J
American journal of physiology. Cell physiology (2018) 3145: C519-C533. 110 043 IHC-P; tested species: mouse
Syntaxin 4 is concentrated on plasma membrane of astrocytes.
Tao-Cheng JH, Pham A, Yang Y, Winters CA, Gallant PE, Reese TS
Neuroscience (2015) 286: 264-71. 110 043 WB, EM
Background

Syntaxin 4, a member of the SNARE family of proteins, is related to syntaxin 1. Like syntaxin 2 it is predominantly localized to the plasma membrane of a wide variety of cells. Similar to syntaxins 1, 2, and 3, it appears to be involved in the fusion of transport vesicles with the plasma membrane.