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SY SY - Synaptic Systems SY SY - Synaptic Systems

VAMP 7 - 232 011

A tetanus neurotoxin-insensitive vesicle-associated membrane protein

Monoclonal mouse purified IgG
415.00 USD
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Cat. No. 232 011 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 200 up to 1 : 500 gallery  
IHC: 1 : 100 up to 1 : 200 gallery  
IHC-P/FFPE: not tested yet
Clone 158.2
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to AA 119 to 188 from mouse VAMP7 (UniProt Id: P70280)
Epitop Epitop: AA 119 to 188 from mouse VAMP7 (UniProt Id: P70280)
Reactivity Reacts with: rat (Q9JHW5), mouse (P70280), human (P51809).
No signal: zebrafish.
Other species not tested yet.
Specificity Specific for VAMP 7. (K.O. verified)
Datasheet 232_011.pdf


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References for VAMP 7 - 232 011

Comparative study of commercially available and homemade anti-VAMP7 antibodies using CRISPR/Cas9-depleted HeLa cells and VAMP7 knockout mice.
Verraes A, Cholley B, Galli T, Nola S
F1000Research (2018) 7: 1649. 232 011 WB; KO verified; tested species: mouse
Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice.
Willetts L, Felix LC, Jacobsen EA, Puttagunta L, Condjella RM, Zellner KR, Ochkur SI, Kim JD, Luo H, Lee NA, Lee JJ, et al.
Communications biology (2018) 1: 83. 232 011 WB, ICC; KO verified; tested species: human
VAMP-7 links granule exocytosis to actin reorganization during platelet activation.
Koseoglu S, Peters CG, Fitch-Tewfik JL, Aisiku O, Danglot L, Galli T, Flaumenhaft R
Blood (2015) 1265: 651-60. 232 011 WB
Tetanus neurotoxin-insensitive vesicle-associated membrane protein localizes to a presynaptic membrane compartment in selected terminal subsets of the rat brain.
Muzerelle A, Alberts P, Martinez-Arca S, Jeannequin O, Lafaye P, Mazié JC, Galli T, Gaspar P
Neuroscience (2003) 1221: 59-75. 232 011 WB, IHC
Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice.
Willetts L, Felix LC, Jacobsen EA, Puttagunta L, Condjella RM, Zellner KR, Ochkur SI, Kim JD, Luo H, Lee NA, Lee JJ, et al.
Communications biology (2018) 1: 83. 232 011 WB, ICC; KO verified; tested species: human
An actin cytoskeletal barrier inhibits lytic granule release from natural killer cells in patients with Chediak-Higashi syndrome.
Gil-Krzewska A, Saeed MB, Oszmiana A, Fischer ER, Lagrue K, Gahl WA, Introne WJ, Coligan JE, Davis DM, Krzewski K
The Journal of allergy and clinical immunology (2017) : . 232 011 ICC; tested species: human
Tetanus neurotoxin-insensitive vesicle-associated membrane protein localizes to a presynaptic membrane compartment in selected terminal subsets of the rat brain.
Muzerelle A, Alberts P, Martinez-Arca S, Jeannequin O, Lafaye P, Mazié JC, Galli T, Gaspar P
Neuroscience (2003) 1221: 59-75. 232 011 WB, IHC
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com