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SY SY - Synaptic Systems SY SY - Synaptic Systems

α Synuclein - 128 211

A protein involved in Parkinson's and Alzheimer's Disease

Monoclonal mouse purified IgG
415.00 USD
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Cat. No. 128 211 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: 1 : 500 gallery  
ELISA: yes (see remarks)
Clone 354A10
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to AA 126 to 140 from human α-Synuclein (UniProt Id: P37840)
Epitop Epitop: AA 126 to 140 from human α-Synuclein (UniProt Id: P37840)
Reactivity Reacts with: human (P37840), rat (P37377), mouse (O55042), mammals.
Other species not tested yet.
Specificity Specific for α-synuclein, no cross-reactivity to β- and γ-synuclein.

ELISA: This antibody is suitable as capture antibody for sandwich-ELISA with cat. no. 128 003 as detector antibody (protocol for sandwich-ELISA).

Datasheet 128_211.pdf

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References for alpha Synuclein - 128 211

E46K α-synuclein pathological mutation causes cell-autonomous toxicity without altering protein turnover or aggregation.
Íñigo-Marco I, Valencia M, Larrea L, Bugallo R, Martínez-Goikoetxea M, Zuriguel I, Arrasate M
Proceedings of the National Academy of Sciences of the United States of America (2017) 11439: E8274-E8283. 128 211 ICC; tested species: rat
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: | E-Mail: