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SY SY - Synaptic Systems SY SY - Synaptic Systems

Synapsin 2 - 106 203

Peripheral synaptic vesicle proteins; substrate for several protein kinases

Polyclonal rabbit purified antibody
370.00 USD
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Cat. No. 106 203 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining)
IP: yes
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: 1 : 200 gallery  
Immunogen Synthetic peptide corresponding to AA 440 to 458 from rat Synapsin2 (UniProt Id: Q63537-1)
Reactivity Reacts with: human (Q92777), rat (Q63537), mouse (Q64332), pig.
Other species not tested yet.
Specificity Specific for synapsins 2a and 2b, no cross-reactivity to synapsin 1a/b. (K.O. verified)
matching control protein/peptide 106-2P
Datasheet 106_203.pdf


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References for Synapsin 2 - 106 203

A protective role of autophagy in TDCIPP-induced developmental neurotoxicity in zebrafish larvae.
Li R, Zhang L, Shi Q, Guo Y, Zhang W, Zhou B
Aquatic toxicology (Amsterdam, Netherlands) (2018) 199: 46-54. 106 203 WB; tested species: zebrafish
Transgenerational endocrine disruption and neurotoxicity in zebrafish larvae after parental exposure to binary mixtures of decabromodiphenyl ether (BDE-209) and lead.
Chen L, Wang X, Zhang X, Lam PKS, Guo Y, Lam JCW, Zhou B
Environmental pollution (Barking, Essex : 1987) (2017) 230: 96-106. 106 203 WB; tested species: danio rerio
Synapsin IIb as a functional marker of submissive behavior.
Nesher E, Koman I, Gross M, Tikhonov T, Bairachnaya M, Salmon-Divon M, Levin Y, Gerlitz G, Michaelevski I, Yadid G, Pinhasov A, et al.
Scientific reports (2015) 5: 10287. 106 203 WB
Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2.
Chugh D, Ali I, Bakochi A, Bahonjic E, Etholm L, Ekdahl CT
PloS one (2015) 107: e0132366. 106 203 WB, IHC; KO verified
Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae.
Chen L, Yu K, Huang C, Yu L, Zhu B, Lam PK, Lam JC, Zhou B
Environmental science & technology (2012) 4617: 9727-34. 106 203 WB
Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation.
Inoue D, Kimura I, Wakabayashi M, Tsumoto H, Ozawa K, Hara T, Takei Y, Hirasawa A, Ishihama Y, Tsujimoto G
FEBS letters (2012) 58610: 1547-54. 106 203 WB, IP; tested species: mouse
Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation.
Inoue D, Kimura I, Wakabayashi M, Tsumoto H, Ozawa K, Hara T, Takei Y, Hirasawa A, Ishihama Y, Tsujimoto G
FEBS letters (2012) 58610: 1547-54. 106 203 WB, IP; tested species: mouse
ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons.
Shulman Y, Stavsky A, Fedorova T, Mikulincer D, Atias M, Radinsky I, Kahn J, Slutsky I, Gitler D
The Journal of neuroscience : the official journal of the Society for Neuroscience (2015) 353: 985-98. 106 203 ICC
Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2.
Chugh D, Ali I, Bakochi A, Bahonjic E, Etholm L, Ekdahl CT
PloS one (2015) 107: e0132366. 106 203 WB, IHC; KO verified
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com