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Home > Products > 340 003

SERT antibody - 340 003 K.O.

SERT translocates serotonin back from the synaptic cleft into the presynaptic neuron
Rabbit polyclonal purified antibody
Cat. No.: 340 003
Amount: 50 µg
Price: $375.00
Cat. No. 340 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: 1 : 200 up to 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 77 from mouse SERT (UniProt Id: Q60857)
Reactivity Reacts with: rat (P31652), mouse (Q60857).
Other species not tested yet.
Specificity K.O. validated PubMed: 28362488
Data sheet 340_003.pdf

References for SERT - 340 003

Sex and brain region-specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice.
Haase J, Jones AKC, Mc Veigh CJ, Brown E, Clarke G, Ahnert-Hilger G
Journal of neurochemistry (2021) : . 340 003 WB; tested species: mouse
TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis.
Brown E, Mc Veigh CJ, Santos L, Gogarty M, Müller HK, Elfving B, Brayden DJ, Haase J
Neuropharmacology (2018) : . 340 003 WB; tested species: mouse
Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice.
Cataldi S, Follett J, Fox JD, Tatarnikov I, Kadgien C, Gustavsson EK, Khinda J, Milnerwood AJ, Farrer MJ
NPJ Parkinson's disease (2018) 4: 27. 340 003 WB; tested species: mouse
Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.
Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G
ACS chemical neuroscience (2017) 85: 1101-1116. 340 003 WB, EM; KO verified; tested species: mouse,rat
Enoxaparin promotes functional recovery after spinal cord injury by antagonizing PTPRσ.
Ito S, Ozaki T, Morozumi M, Imagama S, Kadomatsu K, Sakamoto K
Experimental neurology (2021) 340: 113679. 340 003 IHC; tested species: rat
The development of synaptic transmission is time-locked to early social behaviors in rats.
Naskar S, Narducci R, Balzani E, Cwetsch AW, Tucci V, Cancedda L
Nature communications (2019) 101: 1195. 340 003 IHC; tested species: rat
Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.
Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G
ACS chemical neuroscience (2017) 85: 1101-1116. 340 003 WB, EM; KO verified; tested species: mouse,rat
Cat. No.: 340 003
Amount: 50 µg
Price: $375.00
Sex and brain region-specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice.
Haase J, Jones AKC, Mc Veigh CJ, Brown E, Clarke G, Ahnert-Hilger G
Journal of neurochemistry (2021) : . 340 003 WB; tested species: mouse
TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis.
Brown E, Mc Veigh CJ, Santos L, Gogarty M, Müller HK, Elfving B, Brayden DJ, Haase J
Neuropharmacology (2018) : . 340 003 WB; tested species: mouse
Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice.
Cataldi S, Follett J, Fox JD, Tatarnikov I, Kadgien C, Gustavsson EK, Khinda J, Milnerwood AJ, Farrer MJ
NPJ Parkinson's disease (2018) 4: 27. 340 003 WB; tested species: mouse
Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.
Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G
ACS chemical neuroscience (2017) 85: 1101-1116. 340 003 WB, EM; KO verified; tested species: mouse,rat
Enoxaparin promotes functional recovery after spinal cord injury by antagonizing PTPRσ.
Ito S, Ozaki T, Morozumi M, Imagama S, Kadomatsu K, Sakamoto K
Experimental neurology (2021) 340: 113679. 340 003 IHC; tested species: rat
The development of synaptic transmission is time-locked to early social behaviors in rats.
Naskar S, Narducci R, Balzani E, Cwetsch AW, Tucci V, Cancedda L
Nature communications (2019) 101: 1195. 340 003 IHC; tested species: rat
Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.
Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G
ACS chemical neuroscience (2017) 85: 1101-1116. 340 003 WB, EM; KO verified; tested species: mouse,rat
WB
ICC
IHC
IHC-P
Background
This serotonin transporter (SERT), also referred to as 5HTT and Slc6a4, is a monoamine transporter protein that transports serotonin back from the synaptic cleft into the presynaptic neuron to terminate the action of this neurotransmitter.
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