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SY SY - Synaptic Systems SY SY - Synaptic Systems

Synaptotagmin 1
lumenal domain - 105 308

Ca2+-sensor on synaptic vesicles, triggers neurotransmitter release

Recombinant rabbit purified IgG
415.00 USD
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Cat. No. 105 308 50 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 200 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: not tested yet
Clone Rb604.2
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to AA 1 to 12 from rat Synaptotagmin1 (UniProt Id: P21707)
Epitop Epitop: AA 1 to 12 from rat Synaptotagmin1 (UniProt Id: P21707)
Reactivity Reacts with: rat (P21707).
No signal: mouse (P46096).
Other species not tested yet.
Specificity Specific for rat synaptotagmin 1, no cross-reactivity to other synaptotagmins.
Remarks

This antibody is intended to be used for direct labeling of recycling synapses in primary neuronal cultures.
The antibody is a chimeric antibody based on the monoclonal mouse antibody clone 604.2. The constant regions of the heavy and light chains have been replaced by rabbit specific sequences. Therefore, the antibody can be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells.

Datasheet 105_308.pdf


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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com