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SY SY - Synaptic Systems SY SY - Synaptic Systems

Abeta-pE11 - 218 603

A major component of neuritic plaques in Alzheimer's disease

Polyclonal rabbit purified antibody
370.00 USD
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Cat. No. 218 603 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 200 (see remarks) gallery  
IHC-P/FFPE: 1 : 100 (see remarks) gallery  
ELISA: yes (see remarks) gallery  
Immunogen Synthetic peptide corresponding to AA 11 to 16 from human Abeta-pE11 (UniProt Id: P05067)
Reactivity Reacts with: human (P05067), rat (P08592), mouse (P12023).
Other species not tested yet.
Specificity Specific for Abeta-pE11.
Remarks

WB: Detects purified Abeta-pE11. complex samples like brain extracts not tested yet. Boil membrane after blotting for 3min.

IHC: Formic acid treatment required recommended protocol.

IHC-P: Formic acid treatment required.

ELISA: Suitable as detector antibody.

Datasheet 218_603.pdf


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References for Abeta-pE11 - 218 603

The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ.
Kalimo H, Lalowski M, Bogdanovic N, Philipson O, Bird TD, Nochlin D, Schellenberg GD, Brundin R, Olofsson T, Soliymani R, Baumann M, et al.
Acta neuropathologica communications (2013) 1: 60. 218 603 IHC; tested species: human
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com