Abeta-pE11 - 218 603A major component of neuritic plaques in Alzheimer's diseasePolyclonal rabbit purified antibody
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370.00 USD select country for shop |
| Cat. No. 218 603 | 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use. |
| Applications |
WB: 1 : 1000 (see remarks) gallery IP: not tested yet ICC: not tested yet IHC: 1 : 200 (see remarks) gallery IHC-P/FFPE: 1 : 100 (see remarks) gallery ELISA: yes (see remarks) gallery |
| Immunogen | Synthetic peptide corresponding to AA 11 to 16 from human Abeta-pE11 (UniProt Id: P05067) |
| Reactivity |
Reacts with: human (P05067), rat (P08592), mouse (P12023). Other species not tested yet. |
| Specificity | Specific for Abeta-pE11. |
| Remarks |
WB: Detects purified Abeta-pE11. complex samples like brain extracts not tested yet. Boil membrane after blotting for 3min. IHC: Formic acid treatment required recommended protocol. IHC-P: Formic acid treatment required. ELISA: Suitable as detector antibody. |
| Datasheet | 218_603.pdf |
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WB
IHC
IHC-P
ELISA
References for Abeta-pE11 - 218 603
The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ.
Kalimo H, Lalowski M, Bogdanovic N, Philipson O, Bird TD, Nochlin D, Schellenberg GD, Brundin R, Olofsson T, Soliymani R, Baumann M, et al.
Acta neuropathologica communications (2013) 1: 60. 218 603 IHC; tested species: human
Kalimo H, Lalowski M, Bogdanovic N, Philipson O, Bird TD, Nochlin D, Schellenberg GD, Brundin R, Olofsson T, Soliymani R, Baumann M, et al.
Acta neuropathologica communications (2013) 1: 60. 218 603 IHC; tested species: human
