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SY SY - Synaptic Systems SY SY - Synaptic Systems

Abeta-pE3 - 218 011BT

A major component of neuritic plaques in Alzheimer's disease

Monoclonal mouse purified IgG
465.00 USD
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Cat. No. 218 011BT 100 µg purified IgG, lyophilized, biotin-labeled. . For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 400 (see remarks)
IHC-P/FFPE: 1 : 100
ELISA: yes (see remarks)
Label biotin
Clone 2-48
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to AA 3 to 7 from human Abeta-pE3 (UniProt Id: P05067)
Epitop Epitop: AA 3 to 7 from human Abeta-pE3 (UniProt Id: P05067)
Reactivity Reacts with: human (P05067), rat (P08592), mouse (P12023).
Other species not tested yet.
Specificity Specific for Abeta-pE3.
Remarks

IHCrecommended protocol

ELISA: This antibody is suitable as detector antibody for sandwich-ELISA with cat. no. 218 111 or 218 511 as capture antibody (protocol for sandwich-ELISA).

Datasheet 218_011bt.pdf


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References for Abeta-pE3 - 218 011BT

Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis.
Wirths O, Erck C, Martens H, Harmeier A, Geumann C, Jawhar S, Kumar S, Multhaup G, Walter J, Ingelsson M, Degerman-Gunnarsson M, et al.
The Journal of biological chemistry (2010) 28553: 41517-24. 218 011BT ELISA
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com