Cat. No.: 308 011
Amount: 100 µg
Price:
$415.00
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| Cat. No. 308 011 |
100 µg purified IgG, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Clone | 2H11 |
| Subtype | IgG1 (λ light chain) |
| Immunogen | Recombinant protein corresponding to AA 1 to 140 from bovine Profilin1 (UniProt Id: P02584) |
| Reactivity |
Reacts with: human (P07737), cow, rabbit, Guinea pig, opossum. No signal: mouse (P62962). Other species not tested yet. |
| Data sheet | 308_011.pdf |
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Profilins are small proteins (14-17 kDa) which are involved in the regulation of the cellular microfilament system. They are associated with highly dynamic microfilament structures present at cellular membranes. Profilins have been found together with lamellipodia, focal adhesions, surface ruffles and on intracellular vesicles and have been shown to interact with different cytoskeleton proteins like actin, gephyrin and the Arp 2/3 complex. Recently a tumor suppression activity has been described for profilin.