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SY SY - Synaptic Systems SY SY - Synaptic Systems

Parvalbumin - 195 004

A calcium binding protein

Polyclonal Guinea pig antiserum
350.00 USD
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Cat. No. 195 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: yes
ICC: not tested yet
IHC: 1 : 500 up to 1 : 10000 gallery  
IHC-P/FFPE: 1 : 500 gallery  
EM: yes
Immunogen Recombinant protein corresponding to AA 1 to 110 from rat Parvalbumin (UniProt Id: P02625)
Reactivity Reacts with: rat (P02625), mouse (P32848), chicken, zebrafish, sheep, human (P20472).
Other species not tested yet.
Specificity Specific for parvalbumin.
matching control protein/peptide 195-0P
Remarks

WB: Due to its small size a tricine gel is recommended. 195 002 is more sensitive and recommended for westernblotting

Datasheet 195_004.pdf


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References for Parvalbumin - 195 004

Dysregulation of external globus pallidus-subthalamic nucleus network dynamics in parkinsonian mice during cortical slow-wave activity and activation.
Kovaleski RF, Callahan JW, Chazalon M, Wokosin DL, Baufreton J, Bevan MD
The Journal of physiology (2020) : . 195 004 IHC; tested species: mouse
ROCK/PKA inhibition rescues hippocampal hyperexcitability and GABAergic neuron alterations in Oligophrenin-1 Knock-out mouse model of X-linked intellectual disability.
Busti I, Allegra M, Spalletti C, Panzi C, Restani L, Billuart P, Caleo M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 195 004 IHC; tested species: mouse
Altered excitatory transmission onto hippocampal interneurons in the IQSEC2 mouse model of X-linked neurodevelopmental disease.
Sah M, Shore AN, Petri S, Kanber A, Yang M, Weston MC, Frankel WN
Neurobiology of disease (2020) : 104758. 195 004 IHC; tested species: mouse
Ventral hippocampal projections to the medial prefrontal cortex regulate social memory.
Phillips ML, Robinson HA, Pozzo-Miller L
eLife (2019) 8: . 195 004 IHC; tested species: mouse
Maladaptive Downregulation of Autonomous Subthalamic Nucleus Activity following the Loss of Midbrain Dopamine Neurons.
McIver EL, Atherton JF, Chu HY, Cosgrove KE, Kondapalli J, Wokosin D, Surmeier DJ, Bevan MD
Cell reports (2019) 284: 992-1002.e4. 195 004 IHC; tested species: mouse
A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space.
Trouche S, Koren V, Doig NM, Ellender TJ, El-Gaby M, Lopes-Dos-Santos V, Reeve HM, Perestenko PV, Garas FN, Magill PJ, Sharott A, et al.
Cell (2019) : . 195 004 IHC, EM; tested species: mouse
Downregulation of Npas4 in parvalbumin interneurons and cognitive deficits after neonatal NMDA receptor blockade: relevance for schizophrenia.
Shepard R, Heslin K, Hagerdorn P, Coutellier L
Translational psychiatry (2019) 91: 99. 195 004 IHC; tested species: mouse
Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders.
Singh K, Jayaram M, Kaare M, Leidmaa E, Jagomäe T, Heinla I, Hickey MA, Kaasik A, Schäfer MK, Innos J, Lilleväli K, et al.
Scientific reports (2019) 91: 5457. 195 004 IHC; tested species: mouse
Alterations of perineuronal nets in the dorsolateral prefrontal cortex of neuropsychiatric patients.
Alcaide J, Guirado R, Crespo C, Blasco-Ibáñez JM, Varea E, Sanjuan J, Nacher J
International journal of bipolar disorders (2019) 71: 24. 195 004 IHC; tested species: human
Deletion of PLCγ1 in GABAergic neurons increases seizure susceptibility in aged mice.
Kim HY, Yang YR, Hwang H, Lee HE, Jang HJ, Kim J, Yang E, Kim H, Rhim H, Suh PG, Kim JI, et al.
Scientific reports (2019) 91: 17761. 195 004 IHC; tested species: mouse
Dark exposure affects plasticity-related molecules and interneurons throughout the visual system during adulthood.
Carceller H, Guirado R, Nacher J
The Journal of comparative neurology (2019) : . 195 004 IHC; tested species: mouse
Prefrontal parvalbumin cells are sensitive to stress and mediate anxiety-related behaviors in female mice.
Page CE, Shepard R, Heslin K, Coutellier L
Scientific reports (2019) 91: 19772. 195 004 IHC; tested species: mouse
Phase-specific surround suppression in mouse primary visual cortex correlates with figure detection behavior based on phase discontinuity.
Li F, Jiang W, Wang TY, Xie T, Yao H
Neuroscience (2018) : . 195 004 IHC; tested species: mouse
Neurochemical Characterization of PSA-NCAM+ Cells in the Human Brain and Phenotypic Quantification in Alzheimer's Disease Entorhinal Cortex.
Murray HC, Swanson MEV, Dieriks BV, Turner C, Faull RLM, Curtis MA
Neuroscience (2018) 372: 289-303. 195 004 IHC; tested species: human
Supramammillary Nucleus Afferents to the Dentate Gyrus Co-release Glutamate and GABA and Potentiate Granule Cell Output.
Hashimotodani Y, Karube F, Yanagawa Y, Fujiyama F, Kano M
Cell reports (2018) 2510: 2704-2715.e4. 195 004 IHC; tested species: mouse
Somatostatin Interneurons Facilitate Hippocampal-Prefrontal Synchrony and Prefrontal Spatial Encoding.
Abbas AI, Sundiang MJM, Henoch B, Morton MP, Bolkan SS, Park AJ, Harris AZ, Kellendonk C, Gordon JA
Neuron (2018) : . 195 004 IHC; tested species: mouse
Hippocampal CB1 Receptors Control Incidental Associations.
Busquets-Garcia A, Oliveira da Cruz JF, Terral G, Zottola ACP, Soria-Gómez E, Contini A, Martin H, Redon B, Varilh M, Ioannidou C, Drago F, et al.
Neuron (2018) : . 195 004 IHC; tested species: mouse
Automated analysis of images for molecular quantification in immunohistochemistry.
Guirado R, Carceller H, Castillo-Gómez E, Castrén E, Nacher J
Heliyon (2018) 46: e00669. 195 004 IHC; tested species: mouse
VIP-immunoreactive interneurons within circuits of the mouse basolateral amygdala.
Rhomberg T, Rovira-Esteban L, Vikór A, Paradiso E, Kremser C, Nagy-Pál P, Papp OI, Tasan R, Erdélyi F, Szabó G, Ferraguti F, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) : . 195 004 IHC; tested species: mouse
High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics.
Mager T, Lopez de la Morena D, Senn V, Schlotte J, D Errico A, Feldbauer K, Wrobel C, Jung S, Bodensiek K, Rankovic V, Browne L, et al.
Nature communications (2018) 91: 1750. 195 004 IHC; tested species: mouse
Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum.
Viney TJ, Salib M, Joshi A, Unal G, Berry N, Somogyi P
eLife (2018) 7: . 195 004 IHC; tested species: mouse
Non-canonical heterogeneous cellular distribution and co-localization of CaMKIIα and CaMKIIβ in the spinal superficial dorsal horn.
Larsson M
Brain structure & function (2018) 2233: 1437-1457. 195 004 IHC; tested species: rat
GABAAand GABABreceptor subunit localization on neurochemically identified neurons of the human subthalamic nucleus.
Wu XH, Song JJ, Faull RLM, Waldvogel HJ
The Journal of comparative neurology (2018) 5265: 803-823. 195 004 IHC; tested species: human
The synaptic ribbon is critical for sound encoding at high rates and with temporal precision.
Jean P, Lopez de la Morena D, Michanski S, Jaime Tobón LM, Chakrabarti R, Picher MM, Neef J, Jung S, Gültas M, Maxeiner S, Neef A, et al.
eLife (2018) 7: . 195 004 IHC; tested species: mouse
Parvalbumin-producing striatal interneurons receive excitatory inputs onto proximal dendrites from the motor thalamus in male mice.
Nakano Y, Karube F, Hirai Y, Kobayashi K, Hioki H, Okamoto S, Kameda H, Fujiyama F
Journal of neuroscience research (2018) : . 195 004 IHC; tested species: mouse
Development of a systems-based in situ multiplex biomarker screening approach for the assessment of immunopathology and neural tissue plasticity in male rats after traumatic brain injury.
Bogoslovsky T, Bernstock JD, Bull G, Gouty S, Cox BM, Hallenbeck JM, Maric D
Journal of neuroscience research (2017) : . 195 004 IHC; tested species: rat
Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex.
Hillier D, Fiscella M, Drinnenberg A, Trenholm S, Rompani SB, Raics Z, Katona G, Juettner J, Hierlemann A, Rozsa B, Roska B, et al.
Nature neuroscience (2017) 207: 960-968. 195 004 IHC
Ca2+-binding protein 2 inhibits Ca2+-channel inactivation in mouse inner hair cells.
Picher MM, Gehrt A, Meese S, Ivanovic A, Predoehl F, Jung S, Schrauwen I, Dragonetti AG, Colombo R, Van Camp G, Strenzke N, et al.
Proceedings of the National Academy of Sciences of the United States of America (2017) 1149: E1717-E1726. 195 004 IHC; tested species: mouse
Damaged Neocortical Perineuronal Nets Due to Experimental Focal Cerebral Ischemia in Mice, Rats and Sheep.
Härtig W, Mages B, Aleithe S, Nitzsche B, Altmann S, Barthel H, Krueger M, Michalski D
Frontiers in integrative neuroscience (2017) 11: 15. 195 004 IHC; tested species: mouse,rat,sheep
Combining robotic training and inactivation of the healthy hemisphere restores pre-stroke motor patterns in mice.
Spalletti C, Alia C, Lai S, Panarese A, Conti S, Micera S, Caleo M
eLife (2017) 6: . 195 004 IHC; tested species: mouse
Behavior-Dependent Activity and Synaptic Organization of Septo-hippocampal GABAergic Neurons Selectively Targeting the Hippocampal CA3 Area.
Joshi A, Salib M, Viney TJ, Dupret D, Somogyi P
Neuron (2017) 966: 1342-1357.e5. 195 004 IHC
Facilitation of Contextual Fear Extinction by Orexin-1 Receptor Antagonism Is Associated with the Activation of Specific Amygdala Cell Subpopulations.
Flores Á, Herry C, Maldonado R, Berrendero F
The international journal of neuropsychopharmacology (2017) 208: 654-659. 195 004 IHC; tested species: mouse
Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making.
Friedman A, Homma D, Bloem B, Gibb LG, Amemori KI, Hu D, Delcasso S, Truong TF, Yang J, Hood AS, Mikofalvy KA, et al.
Cell (2017) 1715: 1191-1205.e28. 195 004 IHC; tested species: mouse
Projection-Specific Dynamic Regulation of Inhibition in Amygdala Micro-Circuits.
Vogel E, Krabbe S, Gründemann J, Wamsteeker Cusulin JI, Lüthi A
Neuron (2016) 913: 644-51. 195 004 IHC
Abolished perineuronal nets and altered parvalbumin-immunoreactivity in the nucleus reticularis thalami of wildtype and 3xTg mice after experimental stroke.
Härtig W, Appel S, Suttkus A, Grosche J, Michalski D
Neuroscience (2016) 337: 66-87. 195 004 IHC
Local corticotropin releasing hormone (CRH) signals to its receptor CRHR1 during postnatal development of the mouse olfactory bulb.
Garcia I, Bhullar PK, Tepe B, Ortiz-Guzman J, Huang L, Herman AM, Chaboub L, Deneen B, Justice NJ, Arenkiel BR
Brain structure & function (2016) 2211: 1-20. 195 004 IHC
KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.
Fidzinski P, Korotkova T, Heidenreich M, Maier N, Schuetze S, Kobler O, Zuschratter W, Schmitz D, Ponomarenko A, Jentsch TJ
Nature communications (2015) 6: 6254. 195 004 IHC
The loss of Ivy cells and the hippocampal input modulatory O-LM cells contribute to the emergence of hyperexcitability in the hippocampus.
Orbán-Kis K, Szabadi T, Szilágyi T
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie (2015) 561: 155-61. 195 004 IHC
Increased Serotonin Transporter Expression Reduces Fear and Recruitment of Parvalbumin Interneurons of the Amygdala.
Bocchio M, Fucsina G, Oikonomidis L, McHugh SB, Bannerman DM, Sharp T, Capogna M
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2015) 4013: 3015-26. 195 004 IHC
HMGA2, the architectural transcription factor high mobility group, is expressed in the developing and mature mouse cochlea.
Smeti I, Watabe I, Savary E, Fontbonne A, Zine A
PloS one (2014) 92: e88757. 195 004 IHC; tested species: mouse
Reciprocal connectivity between mitral cells and external plexiform layer interneurons in the mouse olfactory bulb.
Huang L, Garcia I, Jen HI, Arenkiel BR
Frontiers in neural circuits (2013) 7: 32. 195 004 IHC
Effects of amyloid-β plaque proximity on the axon initial segment of pyramidal cells.
León-Espinosa G, DeFelipe J, Muñoz A
Journal of Alzheimer's disease : JAD (2012) 294: 841-52. 195 004 IHC
Cracking down on inhibition: selective removal of GABAergic interneurons from hippocampal networks.
Antonucci F, Alpár A, Kacza J, Caleo M, Verderio C, Giani A, Martens H, Chaudhry FA, Allegra M, Grosche J, Michalski D, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 326: 1989-2001. 195 004 IHC
Temporal dynamics of parvalbumin-expressing axo-axonic and basket cells in the rat medial prefrontal cortex in vivo.
Massi L, Lagler M, Hartwich K, Borhegyi Z, Somogyi P, Klausberger T
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3246: 16496-16502. 195 004 IHC
Polysialic acid is required for dopamine D2 receptor-mediated plasticity involving inhibitory circuits of the rat medial prefrontal cortex.
Castillo-Gómez E, Varea E, Blasco-Ibáñez JM, Crespo C, Nacher J
PloS one (2011) 612: e29516. 195 004 IHC; tested species: rat
Differential localization of GABA(A) receptor subunits in relation to rat striatopallidal and pallidopallidal synapses.
Gross A, Sims RE, Swinny JD, Sieghart W, Bolam JP, Stanford IM
The European journal of neuroscience (2011) 335: 868-78. 195 004 IHC
Elevated global SUMOylation in Ubc9 transgenic mice protects their brains against focal cerebral ischemic damage.
Lee YJ, Mou Y, Maric D, Klimanis D, Auh S, Hallenbeck JM
PloS one (2011) 610: e25852. 195 004 IHC
Neuregulin 1 Type I Overexpression Is Associated with Reduced NMDA Receptor-Mediated Synaptic Signaling in Hippocampal Interneurons Expressing PV or CCK.
Kotzadimitriou D, Nissen W, Paizs M, Newton K, Harrison PJ, Paulsen O, Lamsa K
eNeuro () 52: . 195 004 IHC; tested species: mouse
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Larsson M, Broman J
eNeuro () 61: . 195 004 IHC; tested species: rat
A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space.
Trouche S, Koren V, Doig NM, Ellender TJ, El-Gaby M, Lopes-Dos-Santos V, Reeve HM, Perestenko PV, Garas FN, Magill PJ, Sharott A, et al.
Cell (2019) : . 195 004 IHC, EM; tested species: mouse
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com