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Otubain1 antibody - 280 003

Otubain1 is a cysteine protease in the ubiquitin pathway
Rabbit polyclonal purified antibody
Cat. No.: 280 003
Amount: 50 µg
Price: $375.00
Cat. No. 280 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 80 from mouse Otubain1 (UniProt Id: Q7TQI3)
Reactivity Reacts with: rat (B2RYG6), mouse (Q7TQI3).
Other species not tested yet.
Data sheet 280_003.pdf
Cat. No.: 280 003
Amount: 50 µg
Price: $375.00
Background
Ubiquitination of proteins is a dynamic and reversible process that regulates protein stability and turnover in eukaryotes. The removal of ubiquitin is carried out by deubiquitinating (DUB) enzymes which can be subdivided into ubiquitin carboxy-terminal hydrolases (UCHs) and ubiquitin-specific proteases (USPs). The ubiquitin thioesterase Otubain 1 belongs to the latter group of proteins.