Cat. No.: 129 113
Amount: 50 µg
Price:
$380.00
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| Cat. No. 129 113 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to residues near the carboxy terminus of mouse Neuroligin 3 (UniProt Id: Q8BYM5) |
| Reactivity |
Reacts with: rat (Q62889), mouse (Q8BYM5). No signal: zebrafish. Other species not tested yet. |
| Specificity | K.O. validated PubMed: 31002480 |
| Matching control protein/peptide | 129-3P |
| Data sheet | 129_113.pdf |
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Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and neuroligin 4 have been implicated with a rare, heritable form of autism.