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Home > Products > 129 003

Neuroligin1 antibody extracellular domain - 129 003 K.O.

Neuroligins are postsynaptic cell adhesion molecules
Rabbit polyclonal purified antibody
Cat. No.: 129 003
Amount: 50 µg
Price: $375.00
Cat. No. 129 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 46 to 165 from rat Neuroligin1 (UniProt Id: Q62765)
Reactivity Reacts with: rat (Q62765), mouse (Q99K10).
No signal: zebrafish.
Other species not tested yet.
Specificity K.O. validated
Matching control protein/peptide 129-0P
Data sheet 129_003.pdf

References for Neuroligin1 - 129 003

A delay in vesicle endocytosis by a C-terminal fragment of N-cadherin enhances Aβ synaptotoxicity.
Teng Z, Kartalou GI, Dagar S, Fraering PC, Lessmann V, Gottmann K
Cell death discovery (2023) 91: 444. 129 003 WB; tested species: mouse
Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats.
Targa G, Mottarlini F, Rizzi B, Leo D, Caffino L, Fumagalli F
Biomolecules (2023) 133: . 129 003 WB; tested species: rat
A novel synaptic junction preparation for the identification and characterization of cleft proteins.
Burch A, Tao-Cheng JH, Dosemeci A
PloS one (2017) 123: e0174895. 129 003 WB; tested species: rat
Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus.
Dahlhaus R, Hines RM, Eadie BD, Kannangara TS, Hines DJ, Brown CE, Christie BR, El-Husseini A
Hippocampus (2010) 202: 305-22. 129 003 WB
Hemisynapse Formation Between Target Astrocytes and Cortical Neuron Axons in vitro.
Teng Z, Gottmann K
Frontiers in molecular neuroscience (2022) 15: 829506. 129 003 ICC; tested species: mouse
Cat. No.: 129 003
Amount: 50 µg
Price: $375.00
A delay in vesicle endocytosis by a C-terminal fragment of N-cadherin enhances Aβ synaptotoxicity.
Teng Z, Kartalou GI, Dagar S, Fraering PC, Lessmann V, Gottmann K
Cell death discovery (2023) 91: 444. 129 003 WB; tested species: mouse
Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats.
Targa G, Mottarlini F, Rizzi B, Leo D, Caffino L, Fumagalli F
Biomolecules (2023) 133: . 129 003 WB; tested species: rat
A novel synaptic junction preparation for the identification and characterization of cleft proteins.
Burch A, Tao-Cheng JH, Dosemeci A
PloS one (2017) 123: e0174895. 129 003 WB; tested species: rat
Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus.
Dahlhaus R, Hines RM, Eadie BD, Kannangara TS, Hines DJ, Brown CE, Christie BR, El-Husseini A
Hippocampus (2010) 202: 305-22. 129 003 WB
Hemisynapse Formation Between Target Astrocytes and Cortical Neuron Axons in vitro.
Teng Z, Gottmann K
Frontiers in molecular neuroscience (2022) 15: 829506. 129 003 ICC; tested species: mouse
WB
Background

Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and neuroligin 4 have been implicated with a rare, heritable form of autism.
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