Synaptic Systems - Neurobeachin

Cat. No.: 194 003

Amount: 50 µg

Price: $380.00

Cat. No. 194 003	50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 (AP staining) gallery IP: yes ICC: 1 : 1000 gallery IHC: 1 : 500 IHC-P: not tested yet
Immunogen	Recombinant protein corresponding to AA 952 to 1320 from mouse Neurobeachin (UniProt Id: Q9EPN1)
Reactivity	Reacts with: rat, mouse (Q9EPN1). Other species not tested yet.
Remarks	WB: To avoid protein aggregation, do not heat samples for SDS-PAGE. Due to the large size of this protein, we recommend NuPAGE 3-8% Tris-Acetate gels for SDS-PAGE.
Data sheet	194_003.pdf

The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation.
Won S, Incontro S, Li Y, Nicoll RA, Roche KW
Proceedings of the National Academy of Sciences of the United States of America (2019) : . 194 003 WB; tested species: mouse

Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways.
Farzana F, Zalm R, Chen N, Li KW, Grant SG, Smit AB, Toonen RF, Verhage M
Molecular neurobiology (2016) 534: 2112-23. 194 003 WB, ICC

Neurobeachin regulates neurotransmitter receptor trafficking to synapses.
Nair R, Lauks J, Jung S, Cooke NE, de Wit H, Brose N, Kilimann MW, Verhage M, Rhee J
The Journal of cell biology (2013) 2001: 61-80. 194 003 WB, ICC

Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.
Lauks J, Klemmer P, Farzana F, Karupothula R, Zalm R, Cooke NE, Li KW, Smit AB, Toonen R, Verhage M
PloS one (2012) 76: e39420. 194 003 WB, IP, ICC

Dendritic spine formation and synaptic function require neurobeachin.
Niesmann K, Breuer D, Brockhaus J, Born G, Wolff I, Reissner C, Kilimann MW, Rohlmann A, Missler M
Nature communications (2011) 2: 557. 194 003 WB, ICC, IHC

Cat. No.: 194 003

Amount: 50 µg

Price: $380.00

ICC

Background

Protocols

Neurobeachin antibody - 194 003