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NDCBE antibody - 275 003 K.O.

NDCBE is a sodium bicarbonate exchanger
Rabbit polyclonal purified antibody
Cat. No.: 275 003
Amount: 50 µg
Price: $375.00
Cat. No. 275 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: yes gallery  
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 1078 to 1089 from mouse NDCBE (UniProt Id: Q8JZR6)
Reactivity Reacts with: rat (Q6RVG2), mouse (Q8JZR6).
Other species not tested yet.
Specificity K.O. validated
Remarks

WB:  NDCBE aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.

Data sheet 275_003.pdf
Cat. No.: 275 003
Amount: 50 µg
Price: $375.00
Background
The Na+-driven Cl-/HCO3- exchanger or NDCBE, also known as SLC4A8, is a multispanning transmembrane protein that is predominantly expressed in brain. It is involved in the pH regulation in neurons and modulates glutamatergic synaptic vesicle release.