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Home > Products > 116 102

Munc18-2 antibody - 116 102

Munc18 proteins are peripheral membrane protein involved in vesicle docking and fusion
Rabbit polyclonal antiserum
Cat. No.: 116 102
Amount: 200 µl
Price: $360.00
Cat. No. 116 102 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: external data (see remarks)
IHC: external data (see remarks)
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 593 from mouse Munc18-2 (UniProt Id: Q64324)
Reactivity Reacts with: rat (Q62753), mouse (Q64324).
Other species not tested yet.
Specificity Specific for Munc 18-2 with weak cross-reactivity to Munc18-1 and 3.
Remarks

This antibody detects two smaller bands (possible degradation products) of unkown identity.
ICC: This antibody has been successfully applied and published for this method by customers (see application-specific references). It has not been validated using our standard protocols.
IHC: This antibody has been successfully applied and published for this method by customers (see application-specific references). It has not been validated using our standard protocols.
Data sheet 116_102.pdf

References for Munc18-2 - 116 102

A novel association between platelet filamin A and soluble N-ethylmaleimide sensitive factor attachment proteins regulates granule secretion.
Golla K, Paul M, Lengyell TC, Simpson EM, Falet H, Kim H
Research and practice in thrombosis and haemostasis (2023) 74: 100019. 116 102 WB; tested species: mouse
Munc18-1 is essential for neuropeptide secretion in neurons.
Puntman DC, Arora S, Farina M, Toonen RF, Verhage M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2021) : . 116 102 WB; tested species: mouse
Platelet-specific deletion of SNAP23 ablates granule secretion, substantially inhibiting arterial and venous thrombosis in mice.
Williams CM, Li Y, Brown E, Poole AW
Blood advances (2018) 224: 3627-3636. 116 102 WB; tested species: mouse
Involvement of complexin 2 in docking, locking and unlocking of different SNARE complexes during sperm capacitation and induced acrosomal exocytosis.
Tsai PS, Brewis IA, van Maaren J, Gadella BM
PloS one (2012) 73: e32603. 116 102 WB, ICC; tested species: pig
Cat. No.: 116 102
Amount: 200 µl
Price: $360.00
WB