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Home > Products > 126 104

Munc13-1 antibody - 126 104 K.O.

Munc13 proteins are the mammalian homologues of the C. elegans unc-13 gene essential for exocytosis
Guinea pig polyclonal antiserum
Cat. No.: 126 104
Amount: 100 µl
Price: $370.00
Cat. No. 126 104 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: external data (see remarks) gallery  
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 3 to 317 from rat Munc13-1 (UniProt Id: Q62768)
Reactivity Reacts with: rat (Q62768), mouse (Q4KUS2), zebrafish.
Other species not tested yet.
Specificity K.O. validated
Remarks

IHC: This antibody has been successfully applied for this method by our customers using mild fixation (1% PFA at pH 6) according to Lorincz and Nusser 2010 (see gallery). It has not been validated using our standard protocol.
Data sheet 126_104.pdf

References for Munc13-1 - 126 104

Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.
Kuijpers M, Kochlamazashvili G, Stumpf A, Puchkov D, Swaminathan A, Lucht MT, Krause E, Maritzen T, Schmitz D, Haucke V
Neuron (2021) 1092: 299-313.e9. 126 104 WB; tested species: mouse
An opposing function of paralogs in balancing developmental synapse maturation.
Favaro PD, Huang X, Hosang L, Stodieck S, Cui L, Liu YZ, Engelhardt KA, Schmitz F, Dong Y, Löwel S, Schlüter OM, et al.
PLoS biology (2018) 1612: e2006838. 126 104 WB, IHC; tested species: mouse
Cat. No.: 126 104
Amount: 100 µl
Price: $370.00
WB
ICC
IHC
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