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SY SY - Synaptic Systems SY SY - Synaptic Systems

m6A - 202 003

Antibody against N6-methyladenosine modifications of RNA and DNA

Polyclonal rabbit purified antibody
450.00 USD
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Cat. No. 202 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 10000 (AP staining) suitable for Dot Blot blot  
IP: yes (see remarks)
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
ELISA: yes suitable for sandwich-ELISA quantification  
Immunogen N6-methyladenosine fused to BSA.
Reactivity Reacts with: human, rat, mouse, eukaryotes, prokaryotes.
Other species not tested yet.
Specificity Specific for N6-methyladenosine (m6A).
Remarks

IP: Extracts from eukaryotic and prokaryotic cells. Standard protocol for the IP of nuclear extracts is provided with the product.
For the isolation of m6A modified RNA from total or mRNA preparations the protocol according to Dominissini et al. (2013) is recommended.

Datasheet 202_003.pdf


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References for m6A - 202 003

Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides.
Mishima E, Jinno D, Akiyama Y, Itoh K, Nankumo S, Shima H, Kikuchi K, Takeuchi Y, Elkordy A, Suzuki T, Niizuma K, et al.
PloS one (2015) 1011: e0143756. 202 003 WB, DOTBLOT
Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons.
Yao B, Li Y, Wang Z, Chen L, Poidevin M, Zhang C, Lin L, Wang F, Bao H, Jiao B, Lim J, et al.
Molecular cell (2018) : . 202 003 DOTBLOT, IP; tested species: drosophila
Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon.
Ni TK, Elman JS, Jin DX, Gupta PB, Kuperwasser C
Scientific reports (2018) 81: 1415. 202 003 DOTBLOT
A potentially abundant junctional RNA motif stabilized by m6A and Mg2.
Liu B, Merriman DK, Choi SH, Schumacher MA, Plangger R, Kreutz C, Horner SM, Meyer KD, Al-Hashimi HM
Nature communications (2018) 91: 2761. 202 003 DOTBLOT
Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts.
Merkurjev D, Hong WT, Iida K, Oomoto I, Goldie BJ, Yamaguti H, Ohara T, Kawaguchi SY, Hirano T, Martin KC, Pellegrini M, et al.
Nature neuroscience (2018) : . 202 003 DOTBLOT, IP; tested species: mouse
N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications.
Wang Y, Li Y, Yue M, Wang J, Kumar S, Wechsler-Reya RJ, Zhang Z, Ogawa Y, Kellis M, Duester G, Zhao JC, et al.
Nature neuroscience (2018) 212: 195-206. 202 003 DOTBLOT, IP
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.
Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, Zhao BS, Mesquita A, Liu C, Yuan CL, Hu YC, et al.
Nature cell biology (2018) 203: 285-295. 202 003 DOTBLOT, IP
Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels.
Li J, Meng S, Xu M, Wang S, He L, Xu X, Wang X, Xie L
Oncotarget (2018) 93: 3752-3764. 202 003 DOTBLOT; tested species: human
N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena.
Wang Y, Chen X, Sheng Y, Liu Y, Gao S
Nucleic acids research (2017) 4520: 11594-11606. 202 003 DOTBLOT, ICC
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.
Cui Q, Shi H, Ye P, Li L, Qu Q, Sun G, Sun G, Lu Z, Huang Y, Yang CG, Riggs AD, et al.
Cell reports (2017) 1811: 2622-2634. 202 003 DOTBLOT; tested species: human
Arabidopsis m6A demethylase activity modulates viral infection of a plant virus and the m6A abundance in its genomic RNAs.
Martínez-Pérez M, Aparicio F, López-Gresa MP, Bellés JM, Sánchez-Navarro JA, Pallás V
Proceedings of the National Academy of Sciences of the United States of America (2017) 11440: 10755-10760. 202 003 DOTBLOT, IP
Reduced m6A mRNA methylation is correlated with the progression of human cervical cancer.
Wang X, Li Z, Kong B, Song C, Cong J, Hou J, Wang S
Oncotarget (2017) 858: 98918-98930. 202 003 DOTBLOT
Transcriptome-wide N 6 -methyladenosine methylome profiling of porcine muscle and adipose tissues reveals a potential mechanism for transcriptional regulation and differential methylation pattern.
Tao X, Chen J, Jiang Y, Wei Y, Chen Y, Xu H, Zhu L, Tang G, Li M, Jiang A, Shuai S, et al.
BMC genomics (2017) 181: 336. 202 003 DOTBLOT, IP
RNA m6A methylation regulates the ultraviolet-induced DNA damage response.
Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, et al.
Nature (2017) 5437646: 573-576. 202 003 DOTBLOT, ICC
Mouse Maternal High-Fat Intake Dynamically Programmed mRNA m⁶A Modifications in Adipose and Skeletal Muscle Tissues in Offspring.
Li X, Yang J, Zhu Y, Liu Y, Shi X, Yang G
International journal of molecular sciences (2016) 178: . 202 003 DOTBLOT
DNA N6-methyladenine demethylase ALKBH1 enhances osteogenic differentiation of human MSCs.
Zhou C, Liu Y, Li X, Zou J, Zou S
Bone research (2016) 4: 16033. 202 003 DOTBLOT
Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides.
Mishima E, Jinno D, Akiyama Y, Itoh K, Nankumo S, Shima H, Kikuchi K, Takeuchi Y, Elkordy A, Suzuki T, Niizuma K, et al.
PloS one (2015) 1011: e0143756. 202 003 WB, DOTBLOT
Genome-wide detection of high abundance N6-methyladenosine sites by microarray.
Li Y, Wang Y, Zhang Z, Zamudio AV, Zhao JC
RNA (New York, N.Y.) (2015) 218: 1511-8. 202 003 DOTBLOT
Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome.
Linder B, Grozhik AV, Olarerin-George AO, Meydan C, Mason CE, Jaffrey SR
Nature methods (2015) 128: 767-72. 202 003 DOTBLOT, IP; tested species: human,mouse
The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation.
Zhang M, Zhang Y, Ma J, Guo F, Cao Q, Zhang Y, Zhou B, Chai J, Zhao W, Zhao R
PloS one (2015) 107: e0133788. 202 003 DOTBLOT; tested species: mouse
DNA Methylation on N6-Adenine in C. elegans.
Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu CH, Aravind L, He C, Shi Y
Cell (2015) 1614: 868-78. 202 003 DOTBLOT, IP
m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency.
Chen T, Hao YJ, Zhang Y, Li MM, Wang M, Han W, Wu Y, Lv Y, Hao J, Wang L, Li A, et al.
Cell stem cell (2015) 163: 289-301. 202 003 DOTBLOT, IP
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
Zhao X, Yang Y, Sun BF, Shi Y, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, et al.
Cell research (2014) 2412: 1403-19. 202 003 DOTBLOT, IP
Methylation by NSun2 represses the levels and function of microRNA 125b.
Yuan S, Tang H, Xing J, Fan X, Cai X, Li Q, Han P, Luo Y, Zhang Z, Jiang B, Dou Y, et al.
Molecular and cellular biology (2014) 3419: 3630-41. 202 003 DOTBLOT
Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.
Meyer KD, Saletore Y, Zumbo P, Elemento O, Mason CE, Jaffrey SR
Cell (2012) 1497: 1635-46. 202 003 DOTBLOT, IP
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, Yi C, Lindahl T, Pan T, Yang YG, He C, et al.
Nature chemical biology (2011) 712: 885-7. 202 003 DOTBLOT
Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Mendel M, Chen KM, Homolka D, Gos P, Pandey RR, McCarthy AA, Pillai RS
Molecular cell (2018) : . 202 003 IP; tested species: mouse
N6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential.
Yang D, Qiao J, Wang G, Lan Y, Li G, Guo X, Xi J, Ye D, Zhu S, Chen W, Jia W, et al.
Nucleic acids research (2018) : . 202 003 IP; tested species: mouse
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.
Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen C, Hu C, Sheng Y, et al.
Cell stem cell (2018) 222: 191-205.e9. 202 003 IP
mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes.
Wang X, Sun B, Jiang Q, Wu R, Cai M, Yao Y, Liu Q, Shi H, Feng J, Wang Y
International journal of obesity (2005) (2018) : . 202 003 IP; tested species: pig
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, et al.
Molecular cell (2018) 696: 1028-1038.e6. 202 003 IP; tested species: mouse
Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
Weng YL, Wang X, An R, Cassin J, Vissers C, Liu Y, Liu Y, Xu T, Wang X, Wong SZH, Joseph J, et al.
Neuron (2018) 972: 313-325.e6. 202 003 IP; tested species: mouse
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.
Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, Zhao BS, Mesquita A, Liu C, Yuan CL, Hu YC, et al.
Nature cell biology (2018) 203: 285-295. 202 003 DOTBLOT, IP
Viral and cellular N6-methyladenosine and N6,2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle.
Tan B, Liu H, Zhang S, da Silva SR, Zhang L, Meng J, Cui X, Yuan H, Sorel O, Zhang SW, Huang Y, et al.
Nature microbiology (2018) 31: 108-120. 202 003 IP
N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications.
Wang Y, Li Y, Yue M, Wang J, Kumar S, Wechsler-Reya RJ, Zhang Z, Ogawa Y, Kellis M, Duester G, Zhao JC, et al.
Nature neuroscience (2018) 212: 195-206. 202 003 DOTBLOT, IP
SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function.
Du Y, Hou G, Zhang H, Dou J, He J, Guo Y, Li L, Chen R, Wang Y, Deng R, Huang J, et al.
Nucleic acids research (2018) : . 202 003 IP; tested species: human
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.
Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, et al.
Genes & development (2018) 325-6: 415-429. 202 003 IP; tested species: mouse
METTL3-mediated m6A modification is required for cerebellar development.
Wang CX, Cui GS, Liu X, Xu K, Wang M, Zhang XX, Jiang LY, Li A, Yang Y, Lai WY, Sun BF, et al.
PLoS biology (2018) 166: e2004880. 202 003 IP; tested species: mouse
Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts.
Merkurjev D, Hong WT, Iida K, Oomoto I, Goldie BJ, Yamaguti H, Ohara T, Kawaguchi SY, Hirano T, Martin KC, Pellegrini M, et al.
Nature neuroscience (2018) : . 202 003 DOTBLOT, IP; tested species: mouse
Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning.
Koranda JL, Dore L, Shi H, Patel MJ, Vaasjo LO, Rao MN, Chen K, Lu Z, Yi Y, Chi W, He C, et al.
Neuron (2018) 992: 283-292.e5. 202 003 IP; tested species: mouse
Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion.
Li Z, Qian P, Shao W, Shi H, He XC, Gogol M, Yu Z, Wang Y, Qi M, Zhu Y, Perry JM, et al.
Cell research (2018) : . 202 003 IP; tested species: mouse
Identification and analysis of adenine N6-methylation sites in the rice genome.
Zhou C, Wang C, Liu H, Zhou Q, Liu Q, Guo Y, Peng T, Song J, Zhang J, Chen L, Zhao Y, et al.
Nature plants (2018) 48: 554-563. 202 003 IP
Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons.
Yao B, Li Y, Wang Z, Chen L, Poidevin M, Zhang C, Lin L, Wang F, Bao H, Jiao B, Lim J, et al.
Molecular cell (2018) : . 202 003 DOTBLOT, IP; tested species: drosophila
Transcriptome-wide N 6 -methyladenosine methylome profiling of porcine muscle and adipose tissues reveals a potential mechanism for transcriptional regulation and differential methylation pattern.
Tao X, Chen J, Jiang Y, Wei Y, Chen Y, Xu H, Zhu L, Tang G, Li M, Jiang A, Shuai S, et al.
BMC genomics (2017) 181: 336. 202 003 DOTBLOT, IP
Arabidopsis m6A demethylase activity modulates viral infection of a plant virus and the m6A abundance in its genomic RNAs.
Martínez-Pérez M, Aparicio F, López-Gresa MP, Bellés JM, Sánchez-Navarro JA, Pallás V
Proceedings of the National Academy of Sciences of the United States of America (2017) 11440: 10755-10760. 202 003 DOTBLOT, IP
The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation.
Kudou K, Komatsu T, Nogami J, Maehara K, Harada A, Saeki H, Oki E, Maehara Y, Ohkawa Y
Open biology (2017) 79: . 202 003 IP
Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs.
Zhou C, Molinie B, Daneshvar K, Pondick JV, Wang J, Van Wittenberghe N, Xing Y, Giallourakis CC, Mullen AC
Cell reports (2017) 209: 2262-2276. 202 003 IP
The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells.
Lin S, Choe J, Du P, Triboulet R, Gregory RI
Molecular cell (2016) 623: 335-345. 202 003 IP; tested species: human
Identification of Methylated Deoxyadenosines in Genomic DNA by dA6m DNA Immunoprecipitation.
Koziol MJ, Bradshaw CR, Allen GE, Costa AS, Frezza C
Bio-protocol (2016) 621: . 202 003 IP
Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications.
Koziol MJ, Bradshaw CR, Allen GE, Costa ASH, Frezza C, Gurdon JB
Nature structural & molecular biology (2016) 231: 24-30. 202 003 IP
m(6)A-LAIC-seq reveals the census and complexity of the m(6)A epitranscriptome.
Molinie B, Wang J, Lim KS, Hillebrand R, Lu ZX, Van Wittenberghe N, Howard BD, Daneshvar K, Mullen AC, Dedon P, Xing Y, et al.
Nature methods (2016) 138: 692-8. 202 003 IP
Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification.
Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET
Journal of the American Chemical Society (2015) 1375: 2107-15. 202 003 IP
Widespread occurrence of N6-methyladenosine in bacterial mRNA.
Deng X, Chen K, Luo GZ, Weng X, Ji Q, Zhou T, He C
Nucleic acids research (2015) 4313: 6557-67. 202 003 IP; tested species: e. coli
Decomposition of RNA methylome reveals co-methylation patterns induced by latent enzymatic regulators of the epitranscriptome.
Liu L, Zhang SW, Zhang YC, Liu H, Zhang L, Chen R, Huang Y, Meng J
Molecular bioSystems (2015) 111: 262-74. 202 003 IP
m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency.
Chen T, Hao YJ, Zhang Y, Li MM, Wang M, Han W, Wu Y, Lv Y, Hao J, Wang L, Li A, et al.
Cell stem cell (2015) 163: 289-301. 202 003 DOTBLOT, IP
N6-methyladenosine marks primary microRNAs for processing.
Alarcón CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF
Nature (2015) 5197544: 482-5. 202 003 IP
DNA Methylation on N6-Adenine in C. elegans.
Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu CH, Aravind L, He C, Shi Y
Cell (2015) 1614: 868-78. 202 003 DOTBLOT, IP
N6-adenosine methylation in MiRNAs.
Berulava T, Rahmann S, Rademacher K, Klein-Hitpass L, Horsthemke B
PloS one (2015) 102: e0118438. 202 003 IP
Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.
Geula S, Moshitch-Moshkovitz S, Dominissini D, Mansour AA, Kol N, Salmon-Divon M, Hershkovitz V, Peer E, Mor N, Manor YS, Ben-Haim MS, et al.
Science (New York, N.Y.) (2015) 3476225: 1002-6. 202 003 IP
N6-methyldeoxyadenosine marks active transcription start sites in Chlamydomonas.
Fu Y, Luo GZ, Chen K, Deng X, Yu M, Han D, Hao Z, Liu J, Lu X, Dore LC, Weng X, et al.
Cell (2015) 1614: 879-892. 202 003 IP
Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome.
Linder B, Grozhik AV, Olarerin-George AO, Meydan C, Mason CE, Jaffrey SR
Nature methods (2015) 128: 767-72. 202 003 DOTBLOT, IP; tested species: human,mouse
N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions.
Liu N, Dai Q, Zheng G, He C, Parisien M, Pan T
Nature (2015) 5187540: 560-4. 202 003 IP
Transcriptome-wide N⁶-methyladenosine profiling of rice callus and leaf reveals the presence of tissue-specific competitors involved in selective mRNA modification.
Li Y, Wang X, Li C, Hu S, Yu J, Song S
RNA biology (2014) 119: 1180-8. 202 003 IP
Unique features of the m6A methylome in Arabidopsis thaliana.
Luo GZ, MacQueen A, Zheng G, Duan H, Dore LC, Lu Z, Liu J, Chen K, Jia G, Bergelson J, He C, et al.
Nature communications (2014) 5: 5630. 202 003 IP
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
Zhao X, Yang Y, Sun BF, Shi Y, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, et al.
Cell research (2014) 2412: 1403-19. 202 003 DOTBLOT, IP
Transcriptome-wide mapping of N(6)-methyladenosine by m(6)A-seq based on immunocapturing and massively parallel sequencing.
Dominissini D, Moshitch-Moshkovitz S, Salmon-Divon M, Amariglio N, Rechavi G
Nature protocols (2013) 81: 176-89. 202 003 IP
The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.
Hess ME, Hess S, Meyer KD, Verhagen LA, Koch L, Brönneke HS, Dietrich MO, Jordan SD, Saletore Y, Elemento O, Belgardt BF, et al.
Nature neuroscience (2013) 168: 1042-8. 202 003 IP
RNA-methylation-dependent RNA processing controls the speed of the circadian clock.
Fustin JM, Doi M, Yamaguchi Y, Hida H, Nishimura S, Yoshida M, Isagawa T, Morioka MS, Kakeya H, Manabe I, Okamura H, et al.
Cell (2013) 1554: 793-806. 202 003 IP
DNA binding of the cell cycle transcriptional regulator GcrA depends on N6-adenosine methylation in Caulobacter crescentus and other Alphaproteobacteria.
Fioravanti A, Fumeaux C, Mohapatra SS, Bompard C, Brilli M, Frandi A, Castric V, Villeret V, Viollier PH, Biondi EG
PLoS genetics (2013) 95: e1003541. 202 003 IP
A link between FTO, ghrelin, and impaired brain food-cue responsivity.
Karra E, O'Daly OG, Choudhury AI, Yousseif A, Millership S, Neary MT, Scott WR, Chandarana K, Manning S, Hess ME, Iwakura H, et al.
The Journal of clinical investigation (2013) 1238: 3539-51. 202 003 IP
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.
Dominissini D, Moshitch-Moshkovitz S, Schwartz S, Salmon-Divon M, Ungar L, Osenberg S, Cesarkas K, Jacob-Hirsch J, Amariglio N, Kupiec M, Sorek R, et al.
Nature (2012) 4857397: 201-6. 202 003 IP
Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.
Meyer KD, Saletore Y, Zumbo P, Elemento O, Mason CE, Jaffrey SR
Cell (2012) 1497: 1635-46. 202 003 DOTBLOT, IP
DamIP: using mutant DNA adenine methyltransferase to study DNA-protein interactions in vivo.
Xiao R, Moore DD
Current protocols in molecular biology (2011) Chapter 21: Unit21.21. 202 003 IP
RNA m6A methylation regulates the ultraviolet-induced DNA damage response.
Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, et al.
Nature (2017) 5437646: 573-576. 202 003 DOTBLOT, ICC
N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena.
Wang Y, Chen X, Sheng Y, Liu Y, Gao S
Nucleic acids research (2017) 4520: 11594-11606. 202 003 DOTBLOT, ICC
Genome-wide HP1 binding in Drosophila: developmental plasticity and genomic targeting signals.
de Wit E, Greil F, van Steensel B
Genome research (2005) 159: 1265-73. 202 003 ICC; tested species: drosophila
Antibodies specific for N6-methyladenosine react with intact snRNPs U2 and U4/U6.
Bringmann P, Lührmann R
FEBS letters (1987) 2132: 309-15. 202 003
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com