Cat. No.: 412 005
Amount: 50 µg
Price:
$460.00
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| Cat. No. 412 005 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to AA 267 to 280 from mouse LAMP5 (UniProt Id: Q9D387) |
| Reactivity |
Reacts with: mouse (Q9D387), rat (Q5PPI4). Other species not tested yet. |
| Specificity | K.O. validated |
| Data sheet | 412_005.pdf |
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LAMP5 (Lysosome-associated membrane protein 5), also referred to as BAD-LAMP (Brain and dendritic cell-associated LAMP), is a member of the LAMP family of membrane proteins. However, in contrast to canonical members of this family, that show widespread expression, LAMP5 is, at least in rodents, strictly confined to the CNS where it appears at postnatal stages coincidently with synaptogenesis.
In the human immune system, LAMP5 is expressed at high levels in non-activated plasmacytoid dendritic cells (pDCs), where it allows discrimination of normal from leukemic pDCs in tissue and blood.