Cat. No.: 402 015
Amount: 50 µg
Price:
$460.00
Cat. No. 402 015 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
Applications |
Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IP: not tested yet Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.', $event)" style="cursor: help;">ICC: not tested yet Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IHC: 1 : 500 up to 1 : 1000 gallery Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.', $event)" style="cursor: help;">IHC-P: 1 : 1000 up to 1 : 2000 gallery |
Immunogen | Synthetic peptide corresponding to AA 463 to 482 from rat Kv1.2 (UniProt Id: P63142) |
Reactivity |
Reacts with: rat (P63142), mouse (P63141). Other species not tested yet. |
Data sheet | 402_015.pdf |
A high diversity of K+ channels is formed in the nervous system by heteromeric assembly of subunits encoded by a large number of K+ channel genes. They play an important role in regulating the level of neuronal excitability.
Deletion of Kv 1.2 is lethal in mice and mutations lead to severe consequences including epileptic encephalopathy, intellectual disability and episodic ataxia in humans.