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IP3-receptor type1 peptide - 117-0P

IP3-receptor triggers the release of Ca2+ from intracellular stores
control peptide
Cat. No.: 117-0P
Amount: 100 µg
Price: $105.00
Cat. No. 117-0P 100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control peptides should be stored at -20°C when still lyophilized!
Applications
 
Immunogen Synthetic peptide corresponding to AA 2731 to 2749 from rat IP3-receptortype1 (UniProt Id: P29994)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 117 002, 117 003
Remarks

This control peptide consists of the synthetic peptide (RIGLLGHPPHMNVNPQQPA) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 117-0p.pdf
Cat. No.: 117-0P
Amount: 100 µg
Price: $105.00
Background
Inositol 1, 4, 5 - trisphophate InsP3 is an intracellular messenger that triggers release of Ca2+ from intracellular stores. InsP3 acts by binding to specific receptors localized to endoplasmic reticulum.
There are at least three types of InsP3 receptors, of which the type 1 receptor is the most abundant. All three receptors appear to be widely expressed. Highest levels of the type 1 InsP3 receptors are found in neurons, with very high expression in the Purkinje cells of the cerebellum.
Protocols