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SY SY - Synaptic Systems SY SY - Synaptic Systems

GAPDH - 247 002

A key player in glycolysis

Polyclonal rabbit antiserum
350.00 USD
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Cat. No. 247 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 335 from human GAPDH (UniProt Id: P04406)
Reactivity Reacts with: human (P04406), rat (P04797), mouse (P16858), zebrafish.
Other species not tested yet.
Specificity Specific for GAPDH.
Remarks Well established as a loading control for Western-blotting.
Datasheet 247_002.pdf

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References for GAPDH - 247 002

Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure.
Lombardi M, Parolisi R, Scaroni F, Bonfanti E, Gualerzi A, Gabrielli M, Kerlero de Rosbo N, Uccelli A, Giussani P, Viani P, Garlanda C, et al.
Acta neuropathologica (2019) : . 247 002 WB; tested species: mouse
Inhibition of TNF-α-induced neuronal apoptosis by antidepressants acting through the lysophosphatidic acid receptor LPA1.
Olianas MC, Dedoni S, Onali P
Apoptosis : an international journal on programmed cell death (2019) : . 247 002 WB; tested species: mouse
Overexpression of SNX7 reduces Aβ production by enhancing lysosomal degradation of APP.
Xu S, Zhang L, Brodin L
Biochemical and biophysical research communications (2018) 4951: 12-19. 247 002 WB; tested species: human
The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.
Filipello F, Morini R, Corradini I, Zerbi V, Canzi A, Michalski B, Erreni M, Markicevic M, Starvaggi-Cucuzza C, Otero K, Piccio L, et al.
Immunity (2018) : . 247 002 WB; tested species: mouse
Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin.
Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, Ghirardini E, Filipello F, Moretti M, Gotti C, Annis DS, et al.
The EMBO journal (2018) : . 247 002 WB; tested species: mouse
Muscarinic Acetylcholine Receptors Potentiate 5'-Adenosine Monophosphate-Activated Protein Kinase Stimulation and Glucose Uptake Triggered by Thapsigargin-Induced Store-Operated Ca2+ Entry in Human Neuroblastoma Cells.
Olianas MC, Dedoni S, Onali P
Neurochemical research (2017) : . 247 002 WB; tested species: human
The GABAB positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABAB receptors.
Olianas MC, Dedoni S, Onali P
European journal of pharmacology (2017) 794: 135-146. 247 002 WB
Novel axon projection after stress and degeneration in the Dscam mutant retina.
Fernandes KA, Bloomsburg SJ, Miller CJ, Billingslea SA, Merrill MM, Burgess RW, Libby RT, Fuerst PG
Molecular and cellular neurosciences (2016) 71: 1-12. 247 002 WB
Protective properties of lysozyme on β-amyloid pathology: implications for Alzheimer disease.
Helmfors L, Boman A, Civitelli L, Nath S, Sandin L, Janefjord C, McCann H, Zetterberg H, Blennow K, Halliday G, Brorsson AC, et al.
Neurobiology of disease (2015) 83: 122-33. 247 002 WB
REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation.
Garcia-Manteiga JM, Bonfiglio S, Folladori L, Malosio ML, Lazarevic D, Stupka E, Cittaro D, Meldolesi J
Frontiers in cellular neuroscience (2015) 9: 438. 247 002 WB
Type I interferons up-regulate the expression and signalling of p75 NTR/TrkA receptor complex in differentiated human SH-SY5Y neuroblastoma cells.
Dedoni S, Olianas MC, Ingianni A, Onali P
Neuropharmacology (2014) 79: 321-34. 247 002 WB; tested species: human
Growth differentiation factor 5 is a key physiological regulator of dendrite growth during development.
Osório C, Chacón PJ, Kisiswa L, White M, Wyatt S, Rodríguez-Tébar A, Davies AM
Development (Cambridge, England) (2013) 14023: 4751-62. 247 002 WB; tested species: mouse
Interactome of the amyloid precursor protein APP in brain reveals a protein network involved in synaptic vesicle turnover and a close association with Synaptotagmin-1.
Kohli BM, Pflieger D, Mueller LN, Carbonetti G, Aebersold R, Nitsch RM, Konietzko U
Journal of proteome research (2012) 118: 4075-90. 247 002 WB
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: | E-Mail: