Tailor-made Antibodies
and Tools for Life Science

GABA-A receptor beta2 antibody - 224 805

GABA-A receptors are involved in inhibitory neurotransmission
Guinea pig polyclonal purified antibody
Cat. No.: 224 805
Amount: 50 µg
Price: $465.00
Cat. No. 224 805 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: not tested yet
IHC-Fr: 1 : 500 gallery  
IHC-G: 1 : 500 gallery  
EM: external data
Immunogen Recombinant protein corresponding to AA 343 to 430 from rat GABA-A receptor β2 (UniProt Id: P63138)
Reactivity Reacts with: rat (P63138), mouse (P63137).
Other species not tested yet.
Remarks

WB: To avoid protein aggregation, do not heat samples for SDS-PAGE.
IHC-Fr: The following fixatives are possible: acetone, 4% formaldehyde/PFA
IHC-G: The following fixatives are possible: 3% glyoxal, 9% glyoxal

Data sheet 224_805.pdf

References for GABA-A receptor beta2 - 224 805

The TMEM132B-GABAA receptor complex controls alcohol actions in the brain.
Wang G, Peng S, Reyes Mendez M, Keramidas A, Castellano D, Wu K, Han W, Tian Q, Dong L, Li Y, Lu W, et al.
Cell (2024) 18723: 6649-6668.e35. 224 805 ICC; tested species: mouse
Encephalitis patient-derived monoclonal GABAA receptor antibodies cause epileptic seizures.
Kreye J, Wright SK, van Casteren A, Stöffler L, Machule ML, Reincke SM, Nikolaus M, van Hoof S, Sanchez-Sendin E, Homeyer MA, Cordero Gómez C, et al.
The Journal of experimental medicine (2021) 21811: . 224 805 ICC, IHC; tested species: mouse,rat
Cat. No.: 224 805
Amount: 50 µg
Price: $465.00