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SY SY - Synaptic Systems SY SY - Synaptic Systems

Endophilin 1 - 159 002

An SH3 domain protein involved in clathrin mediated endocytosis

Polyclonal rabbit antiserum
350.00 USD
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Cat. No. 159 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 10000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: 1 : 1000 gallery  
Immunogen Synthetic peptide corresponding to AA 256 to 276 from mouse Endophilin1 (UniProt Id: Q62420)
Reactivity Reacts with: rat (O35179), mouse (Q62420).
Other species not tested yet.
Specificity Specific for endophilin 1. (K.O. verified)
matching control protein/peptide 159-0P
Datasheet 159_002.pdf


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References for Endophilin 1 - 159 002

VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context.
Richter K, Schmutz I, Darna M, Zander JF, Chavan R, Albrecht U, Ahnert-Hilger G
Neuroscience (2018) 371: 29-37. 159 002 WB; tested species: mouse
Endophilin A1 Promotes Actin Polymerization in Dendritic Spines Required for Synaptic Potentiation.
Yang Y, Chen J, Guo Z, Deng S, Du X, Zhu S, Ye C, Shi YS, Liu JJ
Frontiers in molecular neuroscience (2018) 11: 177. 159 002 WB, ICC, IHC; KO verified; tested species: mouse
Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons.
Cao M, Wu Y, Ashrafi G, McCartney AJ, Wheeler H, Bushong EA, Boassa D, Ellisman MH, Ryan TA, De Camilli P
Neuron (2017) 934: 882-896.e5. 159 002 WB; tested species: mouse
A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons.
Wahl S, Katiyar R, Schmitz F
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3325: 10278-300. 159 002 WB, ICC
Endophilin A1 Promotes Actin Polymerization in Dendritic Spines Required for Synaptic Potentiation.
Yang Y, Chen J, Guo Z, Deng S, Du X, Zhu S, Ye C, Shi YS, Liu JJ
Frontiers in molecular neuroscience (2018) 11: 177. 159 002 WB, ICC, IHC; KO verified; tested species: mouse
Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System.
Murdoch JD, Rostosky CM, Gowrisankaran S, Arora AS, Soukup SF, Vidal R, Capece V, Freytag S, Fischer A, Verstreken P, Bonn S, et al.
Cell reports (2016) 174: 1071-1086. 159 002 ICC; tested species: mouse
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 159 002 ICC, IHC; tested species: mouse,rat
A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons.
Wahl S, Katiyar R, Schmitz F
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3325: 10278-300. 159 002 WB, ICC
Endophilin A1 Promotes Actin Polymerization in Dendritic Spines Required for Synaptic Potentiation.
Yang Y, Chen J, Guo Z, Deng S, Du X, Zhu S, Ye C, Shi YS, Liu JJ
Frontiers in molecular neuroscience (2018) 11: 177. 159 002 WB, ICC, IHC; KO verified; tested species: mouse
Evidence for a Clathrin-independent mode of endocytosis at a continuously active sensory synapse.
Fuchs M, Brandstätter JH, Regus-Leidig H
Frontiers in cellular neuroscience (2014) 8: 60. 159 002 IHC, EM; tested species: rat
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 159 002 ICC, IHC; tested species: mouse,rat
Evidence for a Clathrin-independent mode of endocytosis at a continuously active sensory synapse.
Fuchs M, Brandstätter JH, Regus-Leidig H
Frontiers in cellular neuroscience (2014) 8: 60. 159 002 IHC, EM; tested species: rat
Endosomal sorting of readily releasable synaptic vesicles.
Hoopmann P, Punge A, Barysch SV, Westphal V, Bückers J, Opazo F, Bethani I, Lauterbach MA, Hell SW, Rizzoli SO
Proceedings of the National Academy of Sciences of the United States of America (2010) 10744: 19055-60. 159 002
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com