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DARPP32 antibody - 382 003

DARPP32 is a dopamine and cAMP regulated phosphoprotein
Rabbit polyclonal purified antibody
Cat. No.: 382 003
Amount: 50 µg
Price: $455.00
Cat. No. 382 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: 1 : 500 up to 1 : 1000 gallery  
Immunogen Synthetic peptide corresponding to AA 148 to 166 from mouse Darpp32 (UniProt Id: Q60829)
Reactivity Reacts with: rat (Q60829), mouse (Q6J4I0).
Other species not tested yet.
Matching control protein/peptide 382-0P
Data sheet 382_003.pdf
Cat. No.: 382 003
Amount: 50 µg
Price: $455.00
Background
The dopamine and cAMP regulated phosphoprotein 32 kDa (DARPP 32), also known as PPP1R1B, is phosphorylated in a dopamine dependent manner. Stimulation of the dopamine receptor DRD 1 increases cAMP levels resulting in DARPP 32 phosphorylation. It is a commonly used marker for striatal medium spiny neurons (MSNs).