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SY SY - Synaptic Systems SY SY - Synaptic Systems

Abeta 38 - 218 421

A major component of neuritic plaques in Alzheimer's disease

Monoclonal mouse purified IgG
415.00 USD
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Cat. No. 218 421 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 (see remarks) gallery  
IHC-P/FFPE: 1 : 200 (see remarks) gallery  
Clone 326F12
Subtype IgG2b (κ light chain)
Immunogen Synthetic peptide corresponding to AA 33 to 38 from human Abeta38 (UniProt Id: P05067)
Epitop Epitop: AA 33 to 38 from human Abeta38 (UniProt Id: P05067)
Reactivity Reacts with: human.
Other species not tested yet.
Specificity Specific for Abeta 38
Remarks

WB: Detects specifically 20 ng of purified Abeta 38. Complex samples like brain extracts still have to be tested. Boil membrane after blotting for 3min.

IHC: Formic acid treatment required recommended protocol.

IHC-P: Formic acid treatment required.

Datasheet 218_421.pdf


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References for Abeta 38 - 218 421

Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models.
Reinert J, Richard BC, Klafki HW, Friedrich B, Bayer TA, Wiltfang J, Kovacs GG, Ingelsson M, Lannfelt L, Paetau A, Bergquist J, et al.
Acta neuropathologica communications (2016) 4: 24. 218 421 IHC-P
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com