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SY SY - Synaptic Systems SY SY - Synaptic Systems

Abeta 38 - 218 411

A major component of neuritic plaques in Alzheimer's disease

Monoclonal mouse purified IgG
415.00 USD
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Cat. No. 218 411 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 (see remarks) gallery  
IHC-P/FFPE: 1 : 250 (see remarks) gallery  
ELISA: yes , suitable as detector and capture antibody . gallery  
Clone 67B8
Subtype IgG2a
Immunogen Synthetic peptide corresponding to AA 33 to 38 from human Abeta38 (UniProt Id: P05067)
Epitop Epitop: AA 33 to 38 from human Abeta38 (UniProt Id: P05067)
Reactivity Reacts with: human (P05067).
Other species not tested yet.
Specificity Specific for Abeta 38
Remarks

WB: Detects specifically 1 ng of purified Abeta 38. Complex samples like brain extracts still have to be tested. Boil membrane after blotting for 3min.

IHC: Formic acid treatment required recommended protocol.

IHC-P: Formic acid treatment required.

Datasheet 218_411.pdf


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References for Abeta 38 - 218 411

A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor.
Liu L, Ding L, Rovere M, Wolfe MS, Selkoe DJ
The Journal of cell biology (2019) 2182: 644-663. 218 411 ELISA; tested species: human
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com