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SY SY - Synaptic Systems SY SY - Synaptic Systems

Abeta 38 - 218 403

A major component of neuritic plaques in Alzheimer's disease

Polyclonal rabbit purified antibody
370.00 USD
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Cat. No. 218 403 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (ECL detection) (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: yes (see remarks)
IHC-P/FFPE: 1 : 100 (see remarks) gallery  
ELISA: yes suitable as detector/capture antibody with cat. no. 218 111 as capture/detector antibody for gallery   (protocol)
Immunogen Synthetic peptide corresponding to AA 33 to 38 from human Abeta38 (UniProt Id: P05067)
Reactivity Reacts with: human (P05067), rat (P08592), mouse (P12023).
Other species not tested yet.
Specificity Specific for Abeta 38.
Remarks

WB: Detects purified Abeta 38. Complex samples like brain extracts still have to be tested. Boil membrane after blotting for 3min.

IHC: Formic acid treatment required recommended protocol.

IHC-P: Formic acid treatment required.

Datasheet 218_403.pdf


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References for Abeta 38 - 218 403

Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models.
Reinert J, Martens H, Huettenrauch M, Kolbow T, Lannfelt L, Ingelsson M, Paetau A, Verkkoniemi-Ahola A, Bayer TA, Wirths O
Journal of Alzheimer's disease : JAD (2014) 394: 871-81. 218 403 WB, IHC, ELISA; tested species: human
Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models.
Reinert J, Martens H, Huettenrauch M, Kolbow T, Lannfelt L, Ingelsson M, Paetau A, Verkkoniemi-Ahola A, Bayer TA, Wirths O
Journal of Alzheimer's disease : JAD (2014) 394: 871-81. 218 403 WB, IHC, ELISA; tested species: human
Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models.
Reinert J, Martens H, Huettenrauch M, Kolbow T, Lannfelt L, Ingelsson M, Paetau A, Verkkoniemi-Ahola A, Bayer TA, Wirths O
Journal of Alzheimer's disease : JAD (2014) 394: 871-81. 218 403 WB, IHC, ELISA; tested species: human
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com