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SY SY - Synaptic Systems SY SY - Synaptic Systems

Abeta 38/40/42/43 - 218 111

A major component of neuritic plaques in Alzheimer's disease

Monoclonal mouse purified IgG
415.00 USD
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Cat. No. 218 111 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 500 up to 1 : 1000 (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 (see remarks) gallery  
IHC-P/FFPE: 1 : 200 up to 1 : 500 (see remarks) gallery  
ELISA: yes ; unlabeled only (see remarks) gallery  
Clone NT78
Subtype IgG2b (κ light chain)
Immunogen Synthetic peptide corresponding to AA 1 to 16 from human Abeta (UniProt Id: P05067)
Epitop Epitop: AA 4 to 16 from human Abeta (UniProt Id: P05067)
Reactivity Reacts with: human (P05067), mouse (P12023).
Other species not tested yet.
Specificity Specific for Abeta 38, 40, 42, 43.
Remarks

WB: Boil membrane after blotting for 3min.

IHC: Formic acid treatment required recommended protocol.

IHC-P: Formic acid treatment required.

ELISA: Suitable as capture antibody for sandwich-ELISA with cat. no. 218 011BT as detector antibody (protocol for sandwich-ELISA).

Datasheet 218_111.pdf


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References for Abeta 38/40/42/43 - 218 111

Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis.
Wirths O, Erck C, Martens H, Harmeier A, Geumann C, Jawhar S, Kumar S, Multhaup G, Walter J, Ingelsson M, Degerman-Gunnarsson M, et al.
The Journal of biological chemistry (2010) 28553: 41517-24. 218 111 ELISA
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com