ATP1B2 antibody - 407 002

ATPB2 is the non-catalytic subunit of the Na+/K+ transporting ATPase

Rabbit polyclonal antiserum

Cat. No.: 407 002

Amount: 200 µl

Price: $360.00

Cat. No. 407 002	200 µl antiserum, lyophilized. For reconstitution add 200 µl H₂O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P (FFPE): not tested yet Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section. Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section. Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section. Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section. Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen	Synthetic peptide corresponding to AA 267 to 280 from mouse ATP1B2 (UniProt Id: P14231)
Reactivity	Reacts with: rat (P13638), mouse (P14231). Other species not tested yet.
Specificity	Specific for ATP1B2
Matching control protein/peptide	407-0P
Data sheet	Datasheet 407_002

Cat. No.: 407 002

Amount: 200 µl

Price: $360.00

Background

ATP1B2 is the non-catalytic component of the sodium/potassium-transporting ATPase which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the β-2 subunit is not known. It has been shown to mediates cell adhesion of neurons and astrocytes, and to promote neurite outgrowth.

1 ) Heo S et al., Neurochem. Int. (2012)
2 ) Batiuk MY et al., J. Biol. Chem. (2017)
3 ) Mauri N et al., G3 (Bethesda) (2017)

Protocols

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