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TMEM119 antibody - 400 211

TMEM119 is a microglia specific transmembrane protein
Monoclonal mouse purified IgG
Cat. No.: 400 211
Amount: 100 µg
Price: $415.00
Cat. No. 400 211 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 1000 gallery  
Clone 97G1C1
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to AA 189 to 283 from rat TMEM119 (UniProt Id: B2RYL3)
Reactivity Reacts with: rat (B2RYL3).
Other species not tested yet.
Specificity specific for TMEM 119
Remarks

This antibody is recommended for rat only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely.

Data sheet 400_211.pdf

References for TMEM119 - 400 211

Destructive Effect of Intravitreal Heat Shock Protein 27 Application on Retinal Ganglion Cells and Neurofilament.
Grotegut P, Kuehn S, Dick HB, Joachim SC
International journal of molecular sciences (2020) 212: . 400 211 IHC; tested species: rat
Cat. No.: 400 211
Quantity: 100 µg
Price: $415.00
Destructive Effect of Intravitreal Heat Shock Protein 27 Application on Retinal Ganglion Cells and Neurofilament.
Grotegut P, Kuehn S, Dick HB, Joachim SC
International journal of molecular sciences (2020) 212: . 400 211 IHC; tested species: rat
Background
Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM 119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.