TMEM119 antibody human specific - 400 121

TMEM119 is a microglia specific transmembrane protein

Mouse monoclonal purified IgG

Cat. No.: 400 121

Amount: 100 µg

Price: $415.00

Cat. No. 400 121	100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: not tested yet IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: 1 : 1000 gallery
Clone	26C4B3
Subtype	IgG2a (κ light chain)
Immunogen	Recombinant protein corresponding to AA 194 to 283 from human TMEM119 (UniProt Id: Q4V9L6)
Reactivity	Reacts with: human (Q4V9L6). Other species not tested yet.
Remarks	This antibody is recommended for material from human only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely.
Data sheet	400_121.pdf

Cat. No.: 400 121

Amount: 100 µg

Price: $415.00

IHC-P

Background

Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM 119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.

1 ) Bennett ML, Proceedings of the National Academy of Sciences of the United States of America (2016) 11312: E1738-46.
2 ) Satoh J, Neuropathology : official journal of the Japanese Society of Neuropathology (2016) 361: 39-49.

Protocols

IHC-P

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