Tailor-made Antibodies
and Tools for Live Science
Home|||||||Technical Support|

TMEM119 antibody - 400 003

TMEM119 is a microglia specific transmembrane protein
Polyclonal rabbit purified antibody
Cat. No.: 400 003
Amount: 50 µg
Price: $450.00
Cat. No. 400 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 up to 1 : 1000 (see remarks) gallery  
IHC-P/FFPE: 1 : 1000 gallery  
Immunogen Recombinant protein corresponding to AA 189 to 280 from mouse TMEM119 (UniProt Id: Q8R138)
Reactivity Reacts with: mouse (Q8R138).
Other species not tested yet.
Specificity Specific for TMEM 119.
Remarks

This antibody is recommended for mouse only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely.
IHC: The antibody produces some unspecific background in the cerebellum.

Data sheet 400_003.pdf
Cat. No.: 400 003
Quantity: 50 µg
Price: $450.00
Background
Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM 119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.